Results 21 to 30 of about 640 (208)

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research, 2020
Background: Schistosomiasis, caused by infection with blood fluke schistosomes, is a neglected tropical disease of considerable importance in resource-poor communities throughout the developing world.
Gilda Padalino   +3 more
doaj   +1 more source

Comparative randomised trial of high and conventional doses of praziquantel in the treatment of schistosomiasis mansoni [PDF]

open access: yes, 2010
The efficacy of oral praziquantel in the treatment of schistosomiasis has been considered low by most public health institutions. In this paper, we compared the efficacy of two dosages of praziquantel (80 mg/kg vs.
Ahraby ZM Kansaon   +28 more
core   +3 more sources

In silico prediction of new antimicrobial peptides and proteins as druggable targets towards alternative anti-schistosomal therapy [PDF]

open access: yes, 2021
Schistosomiasis is a debilitating disease caused by a parasitic flatworm found in fresh- water. With the exponential increase in prevalence, Praziquantel (PZQ) remains the only effective treatment drug, however, resistance to PZQ has been reported ...
Abidemi Paul Kappo   +3 more
core   +1 more source

Protein deficiency impairs the schistosomicidal action of praziquantel [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 1998
The synergism between schistosomicidal drugs and the host immune system has been currently described in the literature. Antimonium and potassium tartarate, oxamniquine and praziquantel [PZQ are not as effective in immunocompromised hosts as it is in normal ones].
S. F. Lima   +3 more
openaire   +4 more sources

Acute schistosomiasis mansoni: revisited and reconsidered

open access: yesMemorias do Instituto Oswaldo Cruz, 2010
Acute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. A variety of clinical manifestations appear during the migration of schistosomes in humans: cercarial dermatitis, fever, pneumonia, diarrhoea ...
José Roberto Lambertucci
doaj   +1 more source

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research, 2020
Background: Schistosomiasis, caused by infection with blood fluke schistosomes, is a neglected tropical disease of considerable importance in resource-poor communities throughout the developing world.
Gilda Padalino   +3 more
doaj   +1 more source

Tratamento da cisticercose subcutânea co praziquantel: um novo agente cestoidicida [PDF]

open access: yes, 1984
Twenty adult patients presenting dermal cysticercosis without cerebral or ocular involvement were treated with praziquantel. The first eleven cases received 60 mg/kg/day and the last nine cases 30 mg/kg/day.
Baranski, Miroslau Constante
core   +4 more sources

Mass deworming for soil‐transmitted helminths and schistosomiasis among pregnant women: A systematic review and individual participant data meta‐analysis

open access: yesCampbell Systematic Reviews, Volume 15, Issue 3, September 2019., 2019
Abstract The objective of the review is to use individual participant data (IPD) meta‐analysis to explore the effect of mass deworming during pregnancy. We developed a search strategy and searched the databases till March 2018. We included individually randomised controlled trials; cluster randomised controlled trials and quasi randomised studies ...
R. A. Salam   +7 more
wiley   +1 more source

Avaliação terapêutica duplo-cega baseada na técnica do oograma quantitativo, comparando praziquantel com oxamniquine na esquistossomose mansônica humana [PDF]

open access: yes, 1986
Um total de 54 pacientes adultos, com esquistossomose mansônica crônica, nas formas intestinal ou hepatintestinal, participou de um ensaio clínico duplo-cego, para comparar o praziquantel com a oxamniquine.
Cunha, Aloisio Sales da   +1 more
core   +4 more sources

Parasitological diagnosis of schistosomiasis mansoni: fecal examination and rectal biopsy

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Even with all progress in the search of sensitive and methods for the immunological diagnosis of schistosomiasis, the microscopic detection of eggs of the parasite in the stool still remains the most widely used tool for the actual diagnosis of active ...
Ana Lúcia Teles Rabello
doaj   +1 more source

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