Results 21 to 30 of about 495 (168)
Response of drug resistant isolates of Schistosoma mansoni to antischistosomal agents
Memorias do Instituto Oswaldo Cruz, 1993 The susceptibility of four isolates of Schistosoma mansoni (BH, MAP, MPR-1 and K) to four multiple doses of anti-schistosomal agents (hycanthone, niridazole, oxamniquire, and praziquantel) were evaluated in infected female Swiss albino mice.
Kristen M. Drescher +5 more
doaj +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 1993 Three distinct syndromes caused by schistosomiasis have been described: cercarial dermatitis or swimmer's itch, acute schistosomiasis or Katayama fever, and chronic schistosomiasis. Complications of acute schistosomiasis have also been reported.
J. R. Lambertucci
doaj +1 more source
Campbell Systematic Reviews, Volume 12, Issue 1, Page 1-383, 2016., 2016 This review evaluates the effects of mass deworming for soil‐transmitted helminths on growth, educational achievement, cognition, school attendance, quality of life and adverse effects in children in endemic helminth areas. Mass deworming for soil‐transmitted helminths probably has little to no effect on weight, height, school attendance, cognition ...
Vivian A. Welch +14 more
wiley +1 more source
The Scientific World Journal, Volume 2012, Issue 1, 2012., 2012 Previous studies conducted with the imidazolidinic derivative 3‐benzyl‐5‐(4‐chloro‐arylazo)‐4‐thioxo‐imidazolidin‐2‐one (LPSF‐PT05) show outstanding activity against adult Schistosoma mansoni worms in vitro. In the first phase of this study, S. mansoni‐infected mice were treated, orally, with 100 mg/Kg of the LPSF‐PT05 in three formulations: Tween 80 ...
Andréa Cristina Apolinário da Silva +11 more
wiley +1 more source
Frontiers in Genetics, 2014 Schistosoma mansoni is a parasitic plathyhelminth responsible for intestinal schistosomiasis (or bilharziasis), a disease affecting 67 million people worldwide and causing an important economic burden. The schistosomicides hycanthone, and its later proxy
David eRoquis +10 more
doaj +1 more source
Pseudotumoral form of neuroschistosomiasis: report of three cases
Brazilian Journal of Infectious DiseasesCentral nervous system (CSN) involvement in schistosomiasis is an ectopic manifestation with a large variety of clinical forms, including pseudotumoral, which occurs in isolated cases and is rare.
Antonio S. Andrade Filho +8 more
doaj +1 more source
Novel Therapeutic and Prevention Approaches for Schistosomiasis: Review
Journal of Advanced Research, 2013 Schistosomiasis is a debilitating disease affecting approximately 600 million people in 74 developing countries, with 800 million, mostly children at risk. To circumvent the threat of having praziquantel (PZQ) as the only drug used for treatment, several
Rashika A.F. El Ridi +1 more
doaj +1 more source
Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China
British Journal of Pharmacology, Volume 182, Issue 20, Page 4741-4760, October 2025.Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang +5 more
wiley +1 more source
Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates
Protein Science, Volume 34, Issue 6, June 2025.Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva +12 more
wiley +1 more source
, 2018 Campbell Systematic Reviews, Volume 14, Issue 1, Page 1-22, 2018.
Rehana A Salam +6 more
wiley +1 more source