Results 31 to 40 of about 640 (208)

Anti-inflammatory and antinociceptive activities of indole–imidazolidine derivatives [PDF]

, 2011
Non-steroidal anti-inflammatory drugs (NSAIDs) represent a group of approximately 50 different medicines that are widely prescribed for the management of inflammation and that exhibit variable anti-inflammatory, anti-pyretic and analgesic activities ...
Cavalcanti Colaço, Nathália, da Rocha Pitta, Ivan, da Silva Guerra, Aline Stamford Henrique, do Carmo Alves de Lima, Maria, do Nascimento Malta, Diana Jussara, Galdino, Suely Lins, Gonçalves-Silva, Teresinha, Morais Laranjeira, Luana Priscilla, Souza Maia, Maria Bernadete   +8 more
core   +1 more source

Deworming and adjuvant interventions for improving the developmental health and well‐being of children in low‐ and middle‐income countries: a systematic review and network meta‐analysis

Campbell Systematic Reviews, Volume 12, Issue 1, Page 1-383, 2016., 2016
This review evaluates the effects of mass deworming for soil‐transmitted helminths on growth, educational achievement, cognition, school attendance, quality of life and adverse effects in children in endemic helminth areas. Mass deworming for soil‐transmitted helminths probably has little to no effect on weight, height, school attendance, cognition ...
Vivian A. Welch, Elizabeth Ghogomu, Alomgir Hossain, Shally Awasthi, Zulfi Bhutta, Chisa Cumberbatch, Robert Fletcher, Jessie McGowan, Shari Krishnaratne, Elizabeth Kristjansson, Salim Sohani, Shalini Suresh, Peter Tugwell, Howard White, George Wells   +14 more
wiley   +1 more source

Response of drug resistant isolates of Schistosoma mansoni to antischistosomal agents

Memorias do Instituto Oswaldo Cruz, 1993
The susceptibility of four isolates of Schistosoma mansoni (BH, MAP, MPR-1 and K) to four multiple doses of anti-schistosomal agents (hycanthone, niridazole, oxamniquire, and praziquantel) were evaluated in infected female Swiss albino mice.
Kristen M. Drescher, Eugene J. Rogers, John I. Bruce, Naftale Katz, Luiz Candido de Souza Dias, Gerald C. Coles   +5 more
doaj   +1 more source

Acute schistosomiasis: clinical, diagnostic and therapeutic features Esquistossomose aguda: aspectos clínicos, diagnósticos e terapêuticos

Revista do Instituto de Medicina Tropical de São Paulo, 1993
Three distinct syndromes caused by schistosomiasis have been described: cercarial dermatitis or swimmer's itch, acute schistosomiasis or Katayama fever, and chronic schistosomiasis. Complications of acute schistosomiasis have also been reported.
J. R. Lambertucci
doaj   +1 more source

Study of the Activity of 3‐benzyl‐5‐(4‐chloro‐arylazo)‐4‐thioxo‐imidazolidin‐2‐one against Schistosomiasis Mansoni in Mice

The Scientific World Journal, Volume 2012, Issue 1, 2012., 2012
Previous studies conducted with the imidazolidinic derivative 3‐benzyl‐5‐(4‐chloro‐arylazo)‐4‐thioxo‐imidazolidin‐2‐one (LPSF‐PT05) show outstanding activity against adult Schistosoma mansoni worms in vitro. In the first phase of this study, S. mansoni‐infected mice were treated, orally, with 100 mg/Kg of the LPSF‐PT05 in three formulations: Tween 80 ...
Andréa Cristina Apolinário da Silva, Juliana Kelle de Andrade Lemoine Neves, João Inácio Irmão, Vláudia Maria Assis Costa, Valdênia Maria Oliveira Souza, Paloma Lys de Medeiros, Eliete Cavalcanti da Silva, Maria do Carmo Alves de Lima, Ivan da Rocha Pitta, Mônica Camelo Pessoa de Azevedo Albuquerque, Suely Lins Galdino, Issa Nebie   +11 more
wiley   +1 more source

Novel Therapeutic and Prevention Approaches for Schistosomiasis: Review

Journal of Advanced Research, 2013
Schistosomiasis is a debilitating disease affecting approximately 600 million people in 74 developing countries, with 800 million, mostly children at risk. To circumvent the threat of having praziquantel (PZQ) as the only drug used for treatment, several
Rashika A.F. El Ridi, Hatem A.-M. Tallima   +1 more
doaj   +1 more source

Pseudotumoral form of neuroschistosomiasis: report of three cases

Brazilian Journal of Infectious Diseases
Central nervous system (CSN) involvement in schistosomiasis is an ectopic manifestation with a large variety of clinical forms, including pseudotumoral, which occurs in isolated cases and is rare.
Antonio S. Andrade Filho, Aristidez C. Queiroz, Antonio C.C. Freire, Leonardo Conrado S. Lima, Celso A. S. Filho, Isolda N. Amado, Mittermeyer G. Reis, Isis Fernandes Magalhães, Theomira M.A. Carmo   +8 more
doaj   +1 more source

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva, Zhenze Jiang, Chenxi Liu, Pavla Fajtová, Thaiz R. Teixeira, Giovana de Castro Fiorini Maia, Lawrence J. Liu, Nelly El‐Sakkary, Danielle E. Skinner, Ali Syed, Steven C Wang, Conor R. Caffrey, Anthony J. O'Donoghue   +12 more
wiley   +1 more source

PROTOCOL: Mass deworming for soil‐transmitted helminths and schistosomiasis among pregnant women: a systematic review and individual participant data meta‐analysis

, 2018
Campbell Systematic Reviews, Volume 14, Issue 1, Page 1-22, 2018.
Rehana A Salam, Philippa Middleton, Maria Makrides, Vivian Welch, Michelle Gaffey, Simon Cousens, Zulfiqar Bhutta   +6 more
wiley   +1 more source

Survey on the clinical trial results achieved in Brazil comparing praziquantel and oxamniquine in the treatment of mansoni schistosomiasis [PDF]

, 1985
A random, double-blind, parallel group clinical trial program was carried out to compare praziquantel, a recently developed anti-helmintic drug, and oxamniquine, an already established agent for treating mansoni schistosomiasis.
ANDREWS P., BAYER A. G., BINA J. C., BRANCHINI M. L. M., CAMARGO S. de, CARVALHO S. A. de, CARVALHO S. A. de, COUTINHO A. D., COUTINHO A. D., COUTINHO A. D., CUNHA A. S. da, DIAS E. P., DIAS L. C. de S., EMANUEL A., EMANUEL A., FOSTER R., FROHBERG H., Getúlio Leonel de Rezende, GÖNNERT R., HUGG1NS D., JAIMES J. B., KATZ N., KATZ N., KATZ N., KATZ N., KATZ. N., KEYSTONE J. S., PRATA A., PUGH R. N. H., RIM H-J., RIM H-J., SHAW J. R., SILVA L. C. da, SILVA L. C. da, SPINA-FRANÇA A., THOMAS H., WEBBE G., WEGNER D. H. G., ZHU M. P.   +38 more
core   +4 more sources