Results 41 to 50 of about 9,638 (170)

Determination of CD Markers Profile of the Cell Line Infected by S15 Vaccine Strain of Theileria annulata Schizont Using RT-PCR Analysis [PDF]

open access: yesArchives of Razi Institute, 2019
The aim of this study was to identify the cell surface cluster of differentiation (CD) markers of the cell lines infected by Theileria annulata schizont.
H. Modirrousta   +4 more
doaj   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

Giemsa-stained thin blood smear showing an immature schizont.

open access: yes, 2013
Giemsa-stained thin blood smear showing an immature schizont.
Jetsumon Sattabongkot (82977)   +8 more
core   +1 more source

The Microtubule-Stabilizing Protein CLASP1 Associates with the Theileria annulata Schizont Surface via Its Kinetochore-Binding Domain

open access: yesmSphere, 2017
Theileria is an apicomplexan parasite whose presence within the cytoplasm of a leukocyte induces cellular transformation and causes uncontrolled proliferation and clonal expansion of the infected cell.
Sandra Huber   +7 more
doaj   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

open access: yesThe FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju   +2 more
wiley   +1 more source

Additional file 1 of Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response

open access: yes, 2022
Additional file 1: Figure S1. Schizont antibody responses by volunteer location. Violin plots of the anti-schizont antibody units (AU) measured from each of the 142 volunteers at screening by ELISA.
Melissa C. Kapulu (11995884)   +7 more
core   +1 more source

Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase.

open access: yesPLoS ONE, 2012
Signalling by 3'-5'-cyclic guanosine monophosphate (cGMP) exists in virtually all eukaryotes. In the apicomplexan parasite Plasmodium, the cGMP-dependent protein kinase (PKG) has previously been reported to play a critical role in four key stages of the ...
Christine S Hopp   +4 more
doaj   +1 more source

A Genetically Encoded Marker for Imaging of Internal Plasmodium Membranes

open access: yesMolecular Microbiology, EarlyView.
IMMP is a peptide‐based marker that labels internal membranes across multiple stages and species of the malaria‐causing parasite Plasmodium. It works in both live and fixed samples and supports long‐term live‐cell imaging. ABSTRACT Fluorescence microscopy is a powerful tool to analyze the subcellular architecture, and long‐term live‐cell imaging ...
Leah Zink   +9 more
wiley   +1 more source

The prognostic value of schizontaemia in imported Plasmodium falciparum malaria

open access: yesMalaria Journal, 2012
Background In Plasmodium falciparum infection, peripheral parasite counts do not always correlate well with the sequestered parasite burden. As erythrocytes parasitized with mature trophozoites and schizonts have a high tendency to adhere to the ...
van Wolfswinkel Marlies E   +5 more
doaj   +1 more source

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

open access: yesMolecular Microbiology, EarlyView.
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol   +5 more
wiley   +1 more source

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