Results 31 to 40 of about 9,638 (170)
, 2016 A. PfARO co-localizes with the nuclear marker protein, Histone H3 at the early schizont stages. B. PfARO is apically located at the late schizont stages as demonstrated by its co-localization with rhoptry neck marker PfRH2. C.
Alok K. Pandey (228852) +7 more
core +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Release of Falstatin with Schizont Lysis
, 2013 Synchronized late-schizont-infected erythrocytes were cultured in Albumax-free medium. At the indicated time points culture media were collected and concentrated, falstatin was immunoprecipitated with anti-falstatin antiserum and anti-rat IgG beads, the ...
Naresh Singh (108014) +4 more
core +1 more source
The role of Ca2+ in the injury of host cells during the schizogenic stage of E. tenella
Poultry Science, 2022 : Cecal epithelial cell damage is a key factor in host injure during the development of E. tenella. The intracellular free Ca2+ of the host cell is closely related to the invasion, development and proliferation of intracellular parasites, and cell damage.
Xiao-Ling Lv +10 more
doaj +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Lymphocytes and macrophages are infected by Theileria equi, but T cells and B cells are not required to establish infection in vivo. [PDF]
PLoS ONE, 2013 Theileria equi has a biphasic life cycle in horses, with a period of intraleukocyte development followed by patent erythrocytic parasitemia that causes acute and sometimes fatal hemolytic disease. Unlike Theileria spp. that infect cattle (Theileria parva
Joshua D Ramsay +5 more
doaj +1 more source
Integrative Zoology, EarlyView.Apicoplast genomic content and mitochondrial genomic content were found to be strongly correlated (rho = 0.93) for infections going from low to high. Apicoplast and mitochondrial genomic content were deemed as more predictive factors of parasitemia for different infection intensities.
Gaia Porporato +4 more
wiley +1 more source
Schematic diagram of the alterations of cytoskeleton from the ring stage to the schizont stage.
, 2013 Knobs exist from the early trophozoite stage; spectrin network undergoes gradual distortion from ring to schizont stage; and huge meshes exist at the schizont stage.
Jing Yin (143422) +7 more
core +1 more source
Identification and characterisation of a Theileria annulata proline-rich microtubule and SH3 domain-interacting protein (TaMISHIP) that forms a complex with CLASP1, EB1, and CD2AP at the schizont surface. [PDF]
, 2018 Theileria annulata is an apicomplexan parasite that modifies the phenotype of its host cell completely, inducing uncontrolled proliferation, resistance to apoptosis, and increased invasiveness.
Sandra Huber +9 more
core +2 more sources
, 2022 Additional file 5: Table S1. Sub-group analysis of qPCR outcome in relation to anti-schizont antibody responses. Table S2.
Melissa C. Kapulu (11995884) +7 more
core +1 more source