Recruitment of EB1, a master regulator of microtubule dynamics, to the surface of the Theileria annulata schizont. [PDF]
PLoS Pathogens, 2013 The apicomplexan parasite Theileria annulata transforms infected host cells, inducing uncontrolled proliferation and clonal expansion of the parasitized cell population.
Kerry L Woods +7 more
doaj +6 more sources
Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development. [PDF]
PLoS Pathogens, 2020 Ubiquitylation is a common post translational modification of eukaryotic proteins and in the human malaria parasite, Plasmodium falciparum (Pf) overall ubiquitylation increases in the transition from intracellular schizont to extracellular merozoite ...
Judith L Green +20 more
doaj +3 more sources
A
BMC Genomics, 2009 Background The Plasmodium falciparum genome (3D7 strain) published in 2002, revealed ~5,400 genes, mostly based on in silico predictions. Experimental data is therefore required for structural and functional assessments of P.
Charneau Sébastien +10 more
doaj +2 more sources
Analysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions [PDF]
Scientific Reports, 2020 Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted an RNA-seq protocol “DAFT-seq” to sequence
Sasha V. Siegel +8 more
doaj +11 more sources
Proteomic analysis of the Theileria annulata schizont [PDF]
, 2013 The apicomplexan parasite, Theileria annulata, is the causative agent of tropical theileriosis, a devastating lymphoproliferative disease of cattle. The schizont stage transforms bovine leukocytes and provides an intriguing model to study host/pathogen ...
Dobbelaere, D.A.E. +8 more
core +3 more sources
The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. [PDF]
PLoS Biology, 2010 The protozoan parasite Theileria inhabits the host cell cytoplasm and possesses the unique capacity to transform the cells it infects, inducing continuous proliferation and protection against apoptosis.
Conrad von Schubert +5 more
doaj +1 more source
Comparisons of the Sexual Cycles for the Coccidian Parasites Eimeria and Toxoplasma
Frontiers in Cellular and Infection Microbiology, 2020 Toxoplasma gondii and Eimeria spp. are widely prevalent Coccidian parasites that undergo sexual reproduction during their life cycle. T. gondii can infect any warm-blooded animal in its asexual cycle; however, its sexual cycle is restricted to felines ...
Bruno Martorelli Di Genova +1 more
doaj +1 more source
Schistosomiasis coinfection in children influences acquired immune response against Plasmodium falciparum malaria antigens. [PDF]
PLoS ONE, 2010 BACKGROUND: Malaria and schistosomiasis coinfection frequently occurs in tropical countries. This study evaluates the influence of Schistosoma haematobium infection on specific antibody responses and cytokine production to recombinant merozoite surface ...
Tamsir O Diallo +10 more
doaj +1 more source
eLife, 2022 Malaria is caused by infection of the erythrocytes by the parasites Plasmodium. Inside the erythrocytes, the parasites multiply via schizogony, an unconventional cell division mode.
Pengge Qian +8 more
doaj +1 more source
Theileria annulata Cyclophilin1 (TaCyp1) Interacts With Host Cell MED21
Frontiers in Microbiology, 2018 Host cells infected by Theileria annulata schizonts show the character of permanent proliferation in vitro, also named transformation. To explore the molecular mechanism a T.
Shuaiyang Zhao +8 more
doaj +1 more source