Results 1 to 10 of about 28,651 (116)

An abundant merozoite surface protein of Plasmodium falciparum modulates susceptibility to inhibitory antibodies [PDF]

eLife
Malaria merozoite surface proteins (MSPs) are thought to have important roles in red blood cell (RBC) invasion and their exposure on the parasite surface makes them attractive vaccine candidates.
Isabelle G Henshall, Jill Chmielewski, Dimuthu Angage, Ornella Romeo, Keng Heng Lai, Kaitlin R Turland, Nicki Badii, Michael Foley, Robin F Anders, James G Beeson, Danny W Wilson   +10 more
doaj   +2 more sources

Physiology of invasive Plasmodium merozoites [PDF]

Frontiers in Cellular and Infection Microbiology
Malaria, a life-threatening disease caused by Plasmodium parasites, relies on a specialized stage, the merozoite to invade red blood cells and multiply in the bloodstream.
Mansoor A Siddiqui
doaj   +2 more sources

Proliferating toward sex: characterization of cell division of Toxoplasma gondii’s pre-sexual stages [PDF]

mBio
Toxoplasmosis is a disease of worldwide distribution, causing high morbidity and mortality in humans, as well as heavily impacting animal health and the economy.
Florencia Sena, Mohamed-Ali Hakimi, Maria E. Francia   +2 more
doaj   +2 more sources

The Plasmodium berghei merozoite protein PbGAC is critically involved in erythrocyte binding during invasion [PDF]

Parasites & Vectors
Background The invasion of Plasmodium merozoites into host erythrocytes is initiated through specific ligand–receptor interactions. This interaction results in subsequent invasion events, facilitated by the formation of a moving junction via AMA-1 and ...
Junying Gao, Ning Jiang, Yiwei Zhang, Ran Chen, Ying Feng, Xiaoyu Sang, Qijun Chen   +6 more
doaj   +2 more sources

The Cellular and Molecular Interaction Between Erythrocytes and Plasmodium falciparum Merozoites

Frontiers in Cellular and Infection Microbiology, 2022
Plasmodium falciparum is the most lethal human malaria parasite, partly due to its genetic variability and ability to use multiple invasion routes via its binding to host cell surface receptors.
Jessica Molina-Franky, Jessica Molina-Franky, Jessica Molina-Franky, Manuel Elkin Patarroyo, Manuel Elkin Patarroyo, Manuel Elkin Patarroyo, Markus Kalkum, Manuel Alfonso Patarroyo, Manuel Alfonso Patarroyo, Manuel Alfonso Patarroyo   +9 more
doaj   +1 more source

Strain-Dependent Inhibition of Erythrocyte Invasion by Monoclonal Antibodies Against Plasmodium falciparum CyRPA

Frontiers in Immunology, 2021
The highly conserved Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) is a key target for next-generation vaccines against blood-stage malaria.
Anne S. Knudsen, Kasper H. Björnsson, Maria R. Bassi, Melanie R. Walker, Andreas Kok, Bogdan Cristinoi, Anja R. Jensen, Lea Barfod   +7 more
doaj   +1 more source

Identification and Protective Efficacy of Eimeria tenella Rhoptry Kinase Family Protein 17

Animals, 2022
Eimeria tenella encodes a genome of approximately 8000 genes. To date, however, very few data are available regarding E. tenella rhoptry kinase family proteins.
Xiaoxin Liu, Bingjin Mu, Wenbin Zheng, Yijing Meng, Linmei Yu, Wenwei Gao, Xingquan Zhu, Qing Liu   +7 more
doaj   +1 more source

A Novel Thioredoxin-Like Protein of Babesia microti Involved in Parasite Pathogenicity

Frontiers in Cellular and Infection Microbiology, 2022
Babesiosis poses a serious threat to immunocompromised individuals and the major etiological species of Babesia for human babesiosis is Babesia microti. Merozoites are a critical stage in the life cycle of Babesia microti. Several merozoite proteins have
Xianyu Piao, Yu Ma, Shuai Liu, Nan Hou, Qijun Chen, Qijun Chen, Qijun Chen   +6 more
doaj   +1 more source

Evaluation of 4 merozoite antigens as candidate vaccines against Eimeria tenella infection

Poultry Science, 2021
Coccidiosis, caused by parasites of the genus Eimeria, is one of the most widespread and economically detrimental diseases in the global poultry industry.
Xingju Song, Xu Yang, Taotao Zhang, Jing Liu, Qun Liu   +4 more
doaj   +1 more source

Protective Immunity Induced by an Eimeria tenella Whole Sporozoite Vaccine Elicits Specific B-Cell Antigens

Animals, 2021
This study investigated protection against Eimeria tenella following the vaccination of chicks with 5.3 × 106 E. tenella whole-sporozoites emulsified in the nanoparticle adjuvant IMS 1313 N VG Montanide™ (EtSz-IMS1313). One-day-old specific pathogen-free
Marco A. Juárez-Estrada, Amanda Gayosso-Vázquez, Guillermo Tellez-Isaias, Rogelio A. Alonso-Morales   +3 more
doaj   +1 more source