Plasmodium falciparum merozoite surface protein 3 is a target of allele-specific immunity and alleles are maintained by natural selection [PDF]
, 2006 BACKGROUND: Plasmodium falciparum merozoite surface protein (MSP) 3 is an asexual blood-stage malaria vaccine candidate antigen. Sequence polymorphisms divide alleles into 2 major types, but the adaptive and immunological significance of the types has ...
Greenwood, Brian M +13 more
core +5 more sources
Analysis of Polymorphisms in the Merozoite Surface Protein-3? Gene and Two Microsatellite Loci in Sri Lankan Plasmodium vivax: Evidence of Population Substructure in Sri Lanka. [PDF]
, 2011 : Abstract. The geographical distribution of genetic variation in Plasmodium vivax samples (N = 386) from nine districts across Sri Lanka is described using three markers; the P. vivax merozoite surface protein-3?
Alifrangis, M +8 more
core +4 more sources
AP2XII-1 is a negative regulator of merogony and presexual commitment in Toxoplasma gondii
mBio, 2023 A transition from the asexual to sexual development in the widespread intracellular pathogen Toxoplasma gondii requires stage switching in its feline (definitive) host, but the mechanisms governing this process remain elusive.
Fuqiang Fan +4 more
doaj +1 more source
Identification of a Novel RAMA/RON3 Rhoptry Protein Complex in Plasmodium falciparum Merozoites
Frontiers in Cellular and Infection Microbiology, 2021 Malaria causes a half a million deaths annually. The parasite intraerythrocytic lifecycle in the human bloodstream is the major cause of morbidity and mortality. Apical organelles of merozoite stage parasites are involved in the invasion of erythrocytes.
Daisuke Ito +9 more
doaj +1 more source
Poultry Science, 2022 : Though genome sequencing of Eimeria tenella predicts more than 8,000 genes, the molecular functions of many proteins remain unknown. In this study, the coding region corresponding to the mature peptide of a hypothetical protein of E.
Bing-Jin Mu +8 more
doaj +1 more source
Influence of Qingchang Oral Liquid on Second Generation Merozoite of the Chicken Eimeria tenella
Brazilian Journal of Poultry Science, 2021 To determine the effect of Qingchang Oral Liquid (QOL) on second generation merozoite of chicken E. tenella, healthy Roman pink chickens were randomly divided into model group and QOL group (drug group), and both groups of chicks were inoculated with 5 ...
Y Zhiqiang +6 more
doaj +1 more source
Frontiers in Microbiology, 2021 We review the role of signaling pathways in regulation of the key processes of merozoite egress and red blood cell invasion by Plasmodium falciparum and, in particular, the importance of the second messengers, cAMP and Ca2+, and cyclic nucleotide ...
Edwin Lasonder +11 more
doaj +1 more source
Naturally acquired immune responses to P. vivax merozoite surface protein 3α and merozoite surface protein 9 are associated with reduced risk of P. vivax malaria in young Papua New Guinean children [PDF]
, 2013 Plasmodium vivax is the most geographically widespread human malaria parasite. Cohort studies in Papua New Guinea have identified a rapid onset of immunity against vivax-malaria in children living in highly endemic areas. Although numerous P.
Kiniboro, B +36 more
core +2 more sources
eLife, 2017 The most lethal form of malaria in humans is caused by Plasmodium falciparum. These parasites invade erythrocytes, a complex process involving multiple ligand-receptor interactions.
Xavier Sisquella +12 more
doaj +1 more source
Comparisons of the Sexual Cycles for the Coccidian Parasites Eimeria and Toxoplasma
Frontiers in Cellular and Infection Microbiology, 2020 Toxoplasma gondii and Eimeria spp. are widely prevalent Coccidian parasites that undergo sexual reproduction during their life cycle. T. gondii can infect any warm-blooded animal in its asexual cycle; however, its sexual cycle is restricted to felines ...
Bruno Martorelli Di Genova +1 more
doaj +1 more source