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Genome‐Wide Association Study of Symptom Change Following Cognitive Behavioral Therapy for Common Mental Disorders

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Cognitive behavioral therapy (CBT) is a well‐established, evidence‐based treatment for common mental disorders such as depression, anxiety disorders, and obsessive‐compulsive disorder (OCD). However, treatment outcomes vary widely, and a substantial proportion of patients do not achieve sufficient improvement.
Julia Bäckman +41 more
wiley +1 more source

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young +6 more
wiley +1 more source

À l’écoute du soignant : relation de soins et considérations éthiques dans la pratique des soins psychiatriques communautaires [PDF]

, 2012
Un phénomène de résistance au traitement pharmacologique chez les personnes souffrant de maladies psychiatriques graves et persistantes comme la schizophrénie, tel que révélé par la pratique des soins psychiatriques communautaires de première ligne, sert
Cauchon, Marc
core

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra +5 more
wiley +1 more source

Are There Causal Associations Between Obsessive‐Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi‐Directional Mendelian Randomization Study

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton +217 more
wiley +1 more source

ABILIFY®, aripiprazole : premier agoniste partiel dans le traitement de la schizophrénie [PDF]

, 2007
Dans un premier temps, nous nous intéresserons à la schizophrénie : cette maladie touche un nombre important de personnes dans le monde avec des conséquences socio-économiques et de mortalité désastreuses.
Cacaret, Alban
core +1 more source

Distinct Effects of Complement C4A and C4B Copy Numbers in Systemic Sclerosis Serological and Clinical Subtypes

Arthritis &Rheumatology, EarlyView.
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. The variable copy number (CN) of C4 genes and retroviral human endogenous retrovirus K (HERV‐K) element influence its function.
Javier Martínez‐López +156 more
wiley +1 more source

Etude de la prise en charge de la personne âgée en Centre Hospitalier spécialisé en psychiatrie au travers de ses traitements médicamenteux (évaluation au Centre de Santé Mentale Angevin (CESAME)) [PDF]

, 2012
Les personnes âgées sont sujettes avec l avancée en âge à une vulnérabilité tant sur le plan physique que sur le plan psychique. L augmentation de la proportion des ainés s accompagne d une hausse de la demande de soins en psychiatrie.
DESPREZ, Mathilde, ROUSSET, Béatrice
core

Changes in Intrinsic Activity of the Primary Somatosensory Cortex Causally Explain Differences in Emotion Perception in Autism

Autism Research, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is characterized by certain difficulties in emotion‐related processing. Recent research using electroencephalography (EEG) to measure somatosensory evoked potentials during emotion perception has shown reduced embodiment of emotional expressions in autistic compared to neurotypical individuals, independently from
Martina Fanghella +5 more
wiley +1 more source

Perceptions du soutien social reçu par les proches aidants d'une personne atteinte d'un trouble affectif bipolaire [PDF]

, 2017
Le présent mémoire porte sur le soutien social reçu par les proches aidants en santé mentale. Il vise à mieux comprendre la perception qu'ont les proches aidants d'une personne atteinte d'un trouble affectif bipolaire face au soutien social, à déterminer
Lachance, Ève
core

psychosis
clozapine