Results 141 to 150 of about 258,912 (200)

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders

JCPP Advances, EarlyView.
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser, Wangjingyi Liao, Andrea G. Allegrini, Kaili Rimfeld, Thalia C. Eley, Robert Plomin, Margherita Malanchini   +6 more
wiley   +1 more source

The association of the TLR3 SNP rs3775291 with schizophrenia is influenced by age. [PDF]

Front Genet
Wang Y, Peng L, Liu Y, Gao Z, Wang J, Zhang T, Wang Y.   +6 more
europepmc   +1 more source

Disentangling shared and unique effects of parenting on psychopathology: Evidence from two prospective, genetically sensitive cohort studies

JCPP Advances, EarlyView.
Abstract Background Multiple dimensions of parenting–including hostility, conflict, and warmth–are associated with an array of mental disorders in youth. We tested two possible explanations for these associations: Parenting may shape a shared liability to experience many forms of psychopathology (“shared‐liability” hypothesis), or parenting may shape ...
Leah S. Richmond‐Rakerd, Lara Khalifeh, S. Alexandra Burt, Jody M. Ganiban, Rachel E. Hsu, Luke W. Hyde, Sujin Lee, Leslie D. Leve, Misaki N. Natsuaki, Jenae M. Neiderhiser, David Reiss, Daniel S. Shaw, Gabriela L. Suarez, Jasmin Wertz   +13 more
wiley   +1 more source

Prevalence, adherence, and health care resource utilization in schizophrenia: A national and state-level analysis of US Medicaid Beneficiaries. [PDF]

J Manag Care Spec Pharm
Parks J, Xiang P, Patel R, McBride K, Costantino H, Mirza S, Borsos K.   +6 more
europepmc   +1 more source

Alterations in resting‐state functional connectivity relate to psychopathology trajectories during emerging adolescence

JCPP Advances, EarlyView.
Abstract Background A general psychopathology “p‐factor” captures shared variation across psychiatric disorder categories and is associated with dysfunctions in cognitive control. Alterations in resting‐state functional connectivity (RSFC) of cognitive and attentional networks have been associated concurrently with the p‐factor in youth samples ...
Jenna Jones Devine, Garrett R. Hosterman, Jolee Sloss, Adrienne L. Romer   +3 more
wiley   +1 more source

Balancing one's own life with caregiving for a sibling with schizophrenia: A qualitative study. [PDF]

Int J Nurs Stud Adv
Kawaguchi M, Katayama M, Nakamoto A, Morioka H, Kawamura M.   +4 more
europepmc   +1 more source

Transdiagnostic and symptom‐domain associations between mental illnesses and future self‐connectedness versus future self‐valence

JCPP Advances, EarlyView.
Abstract Background Future time perspective dimensions have been linked to various mental illnesses. Given the tendency for mental illnesses to co‐occur, it is necessary to disentangle associations between future‐oriented constructs and shared versus symptom‐domain‐specific psychopathology.
Yi Yang, Ingrid Obsuth, Jean‐Louis van Gelder, Denis Ribeaud, Manuel Eisner, Xinxin Zhu, Aja Louise Murray   +6 more
wiley   +1 more source

The dysconnection hypothesis of schizophrenia: a 30-year update. [PDF]

World Psychiatry
Friston K.
europepmc   +1 more source

Measurement of social and emotional wellbeing and mental health outcomes in first nations children: A systematic review

JCPP Advances, EarlyView.
Abstract Background There is a critical lack of reliable, high‐quality epidemiological data on mental health and/or social and emotional wellbeing (SEWB) outcomes for First Nations children, partly, due to the limited availability of culturally valid assessment tools. This review aims to assess the cultural validity of mental health and SEWB assessment
Maddison O’Gradey‐Lee, Emma McDermott, Lizel‐Antoinette Bertie, Clinton Schultz, Jennifer L. Hudson   +4 more
wiley   +1 more source

Relaxation of Japan's clozapine monitoring system is urgently needed: Adding 10,000 future prescriptions may prevent up to 400 schizophrenia-related suicides and cost 1 death by agranulocytosis. [PDF]

PCN Rep
de Leon J, Kikuchi Y, Yasui-Furukori N.
europepmc   +1 more source