Results 151 to 160 of about 255,128 (240)

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

Fingerprints Encode Risk for Bipolarity. [PDF]

Bipolar Disord
Salvador R, García-León MÁ, Rodriguez-Jimenez R, Del Olmo-Encabo P, Barbosa L, Aquino-Servín A, Sotero-Moreno A, Fatjó-Vilas M, Jaurrieta-Guarner N, Sánchez M, Corte-Souto C, Rojo A, Rebolleda-Gil C, Correa-Ghisays P, Balanzá-Martínez V, Caride-Padilla C, Sarró S, Feria-Raposo I, Sánchez-Cabezudo Á, Jiménez-Rodríguez O, Torres ML, Moreno-Comellas R, Navarro B, Del Olmo-Romero F, Larraz-Romeo JA, Pomarol-Clotet E.   +25 more
europepmc   +1 more source

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

iNew Medicine, EarlyView.
ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang, Linbo Xie, Mengdan Chen, Yi Ji, Yibing Yan, Shanshan Zhou, Panpan Hu, Xingqi Wu, Kai Wang   +8 more
wiley   +1 more source

Alexithymia in Schizophrenia and Psychosis Vulnerability: A Systematic Review and Meta‐Analysis

Journal of Clinical Psychology, Volume 81, Issue 6, Page 410-424, June 2025.
ABSTRACT Aims Disturbances involving impairments in experience and expression of affect are frequently identified in schizophrenia samples. Alexithymia underlies cognitive impairments in identification and expression of affect, further implicated in affect dysregulation.
Ercan Ozdemir, Zhuoni Xiao, Helen Griffiths, Angus MacBeth   +3 more
wiley   +1 more source

Genetic Variants from Large Cohorts and Familial Studies Implicate Common Mechanisms in Schizophrenia. [PDF]

Biology (Basel)
Kanwal A, Pardo JV, Naz S.
europepmc   +1 more source

Differences in patterns of attention deficit/hyperactivity disorder medication use in US children

JCPP Advances, EarlyView.
Abstract Background Understanding attention deficit/hyperactivity disorder (ADHD) medication patterns is crucial for optimizing treatment outcomes. There are limited data on racial, ethnic, gender and socioeconomic treatment differences across longitudinal national samples.
Jennie E. Ryan, Alexander Weigard, Sean Esteban McCabe, Timothy E. Wilens, Philip T. Veliz   +4 more
wiley   +1 more source

Psychopathy traits and their link to emotion recognition impairments in conduct disorder

JCPP Advances, EarlyView.
Abstract Background Neurocognitive models suggest that callous‐unemotional (CU) traits in youths with conduct disorder (CD) are linked to emotion recognition impairments, particularly in identifying distress emotions like fear and sadness. However, CD may be accompanied by grandiose‐manipulative (GM) and/or impulsive‐irresponsible (II) traits in ...
Gregor Kohls, Anka Bernhard, Graeme Fairchild, Christina Stadler, Lucres Jansen, Stephane A. De Brito, Veit Roessner, Christine M. Freitag, Kerstin Konrad, Erik M. Elster   +9 more
wiley   +1 more source

Public stigma of mental illness in Australia: shifts in attitudes across nationally representative surveys in 2011 and 2024. [PDF]

Epidemiol Psychiatr Sci
Morgan A, Ross A, McNaught G, Green R, Reavley NJ.   +4 more
europepmc   +1 more source

Neural correlates of resilience to trauma during adolescence: A multi‐modal study

JCPP Advances, EarlyView.
Abstract Background Understanding resilience mechanisms is important for advancing early intervention strategies, yet research on the neurobiology of resilience in adolescents is limited. The present study examined the brain structural and resting‐state functional connectivity (rsFC) correlates of resilience to internalizing and externalizing symptoms ...
Lu Zhang, Vanessa L. Cropley, Divyangana Rakesh, Sarah Whittle   +3 more
wiley   +1 more source

Effect of transcranial direct current stimulation on semantic memory depends on anodal stimulation sites in patients with schizophrenia. [PDF]

Schizophr Res Cogn
Wada A, Sumiyoshi C, Stickley A, Yoshimura N, Yamada Y, Sumiyoshi T.   +5 more
europepmc   +1 more source