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Schizophrenia [PDF]

open access: yesThe Lancet, 2016
Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. Dysfunction of dopaminergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points to a widespread and variable involvement ...
A. Vita   +4 more
semanticscholar   +9 more sources

Nonsocial and social cognition in schizophrenia: current evidence and future directions

open access: yesWorld Psychiatry, 2019
Cognitive impairment in schizophrenia involves a broad array of nonsocial and social cognitive domains. It is a core feature of the illness, and one with substantial implications for treatment and prognosis.
Michael F Green, Junghee Lee
exaly   +2 more sources

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

open access: yesNature, 2022
Ağan H ŞEkercioğlu   +2 more
exaly   +2 more sources

Biological insights from 108 schizophrenia-associated genetic loci

open access: yesNature, 2014
S. Ripke   +299 more
exaly   +2 more sources

cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia

open access: yesFrontiers in Molecular Neuroscience, 2018
Dopamine is a brain neurotransmitter involved in the pathology of schizophrenia. The dopamine hypothesis states that, in schizophrenia, dopaminergic signal transduction is hyperactive.
Haitao Wang   +2 more
exaly   +2 more sources

Motor deficits in schizophrenia quantified by nonlinear analysis of postural sway. [PDF]

open access: yes, 2012
Motor dysfunction is a consistently reported but understudied aspect of schizophrenia. Postural sway area was examined in individuals with schizophrenia under four conditions with different amounts of visual and proprioceptive feedback: eyes open or ...
Bolbecker, Amanda R.   +6 more
core   +18 more sources

Schizophrenia [PDF]

open access: yesThe Lancet, 2022
Schizophrenia, characterised by psychotic symptoms and in many cases social and occupational decline, remains an aetiological and therapeutic challenge. Contrary to popular belief, the disorder is modestly more common in men than in women. Nor is the outcome uniformly poor.
Jauhar, Sameer   +2 more
openaire   +3 more sources

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