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Schizophrenia [PDF]

open access: yesThe Lancet, 2016
Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. Dysfunction of dopaminergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points to a widespread and variable involvement ...
Michael J Owen   +2 more
openaire   +8 more sources

Learnings from conducting mental health research during 2004 tsunami in Tamil Nadu, India

open access: yesBMC Public Health, 2020
Background The Indian Ocean tsunami experience in 2004 caused a major loss of life and subsequent emotional trauma for survivors. Psychosocial needs in the aftermath of this disaster were extensive, yet the cohesion and effectiveness of response were ...
R. Padmavati   +6 more
doaj   +1 more source

Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia

open access: yesMolecular Brain, 2021
Reductions in the GABAergic neurotransmitter system exist across multiple brain regions in schizophrenia and encompass both pre- and postsynaptic components.
Tertia D. Purves-Tyson   +4 more
doaj   +1 more source

Bullying among children and adolescents in the SAARC countries: A scoping review

open access: yesHeliyon, 2022
Background: Bullying is defined as repetitive and intentional aggression by an individual or group towards other individuals that happens in a power differential between the individuals being bullied and the bullies.
Shiva Prakash Srinivasan   +4 more
doaj   +1 more source

Cognitive and negative symptoms in schizophrenia with L‐Carnosine adjuvant therapy – A randomized double‐blind placebo‐controlled study

open access: yesPharmacology Research & Perspectives, 2023
The antioxidant L‐Carnosine is reported to improve negative and cognitive symptoms in Schizophrenia. A randomized double‐blind placebo‐controlled study was planned to study the effectiveness of adjuvant L‐Carnosine therapy in patients with Schizophrenia.
Hema Tharoor   +5 more
doaj   +1 more source

Association between hypertension, body mass index, and sleep: A cross-sectional study

open access: yesIndian Journal of Mental Health and Neurosciences, 2021
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Aishwarya Gonzalez Cherubal   +2 more
doaj   +1 more source

Schizophrenia

open access: yesNew England Journal of Medicine, 2020
The lifetime prevalence of schizophrenia is 1%. Schizophrenia is among the most severe mental illnesses and gives rise to the highest treatment costs per patient of any disease. It is characterized by frequent relapses, marked impairment of quality of life, and reduced social and work participation.The group entrusted with the creation of the German ...
Matthew L, Goldman   +2 more
openaire   +7 more sources

Frequency of clinical appointments in subjects with emergent suicidal ideation

open access: yesEuropean Psychiatry, 2022
Introduction Schizophrenia is a psychotic disorder strongly associated with suicidal behaviour up to 20-50 times higher than those in the general population.
J. Qian, N. Yasmin, V. Deluca
doaj   +1 more source

Búsqueda De Nuevos Biomarcadores De La Cognición En Esquizofrenia

open access: yesSchizophrenia Research: Cognition, 2015
La búsqueda de biomarcadores en la cognición ha centrado una gran parte de las investigaciones en pacientes con esquizofrenia. La literatura científica es heterogénea y son escasos los estudios disponibles que permitan establecer un modelo integrador de ...
Rafael Penadés   +6 more
doaj   +1 more source

Influence of psychopathology and metabolic parameters on quality of life in patients with first-episode psychosis before and after initial antipsychotic treatment

open access: yesSchizophrenia, 2023
The impact of psychological and physical health on quality of life (QoL) in patients with early psychosis remain relatively unexplored. We evaluated the predictive value of psychopathological and metabolic parameters on QoL in antipsychotic-naïve ...
Anne Sofie A. Dahl   +10 more
doaj   +1 more source

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