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Schizophrenia [PDF]

open access: yesThe Lancet, 2016
Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. Dysfunction of dopaminergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points to a widespread and variable involvement ...
Michael J Owen   +2 more
openaire   +8 more sources

Schizophrenia [PDF]

open access: yesNature Reviews Disease Primers, 2015
Schizophrenia is a chronic psychiatric disorder with a heterogeneous genetic and neurobiological background that influences early brain development, and is expressed as a combination of psychotic symptoms - such as hallucinations, delusions and disorganization - and motivational and cognitive dysfunctions.
Kahn, René S.   +10 more
openaire   +5 more sources

Schizophrenia [PDF]

open access: yesThe Lancet, 2022
Schizophrenia, characterised by psychotic symptoms and in many cases social and occupational decline, remains an aetiological and therapeutic challenge. Contrary to popular belief, the disorder is modestly more common in men than in women. Nor is the outcome uniformly poor.
Jauhar, Sameer   +2 more
openaire   +3 more sources

Schizophrenia

open access: yesNew England Journal of Medicine, 2020
The lifetime prevalence of schizophrenia is 1%. Schizophrenia is among the most severe mental illnesses and gives rise to the highest treatment costs per patient of any disease. It is characterized by frequent relapses, marked impairment of quality of life, and reduced social and work participation.The group entrusted with the creation of the German ...
Matthew L, Goldman   +2 more
openaire   +6 more sources

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