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A nation-wide twin study of social cognition in schizophrenia spectrum disorders

open access: yesnpj Schizophrenia, 2022
We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ).
Cecilie K. Lemvigh   +2 more
doaj   +1 more source

Cognitive control and discourse comprehension in schizophrenia. [PDF]

open access: yes, 2012
Cognitive deficits across a wide range of domains have been consistently observed in schizophrenia and are linked to poor functional outcome (Green, 1996; Carter, 2006). Language abnormalities are among the most salient and include disorganized speech as
Boudewyn, Megan A   +2 more
core   +3 more sources

Schizophrenia in older adults [PDF]

open access: yes, 2011
Although the number of persons over the age of 55 with schizophrenia is expected to double over the next 20 years, the research data on older people with schizophrenia is limited.
American Psychiatric Association   +12 more
core   +2 more sources

Using blood cytokine measures to define high inflammatory biotype of schizophrenia and schizoaffective disorder

open access: yesJournal of Neuroinflammation, 2017
Background Increases in pro-inflammatory cytokines are found in the brain and blood of people with schizophrenia. However, increased cytokines are not evident in all people with schizophrenia, but are found in a subset.
Danny Boerrigter   +11 more
doaj   +1 more source

Nuclear factor kappa B activation appears weaker in schizophrenia patients with high brain cytokines than in non-schizophrenic controls with high brain cytokines

open access: yesJournal of Neuroinflammation, 2020
Background High inflammation status despite an absence of known infection characterizes a subpopulation of people with schizophrenia who suffer from more severe cognitive deficits, less cortical grey matter, and worse neuropathology. Transcripts encoding
Caitlin E. Murphy   +7 more
doaj   +1 more source

Differences in inflammatory marker profiles and cognitive functioning between deficit and nondeficit schizophrenia

open access: yesFrontiers in Immunology, 2022
Deficit schizophrenia (DS) patient is a homogenous subtype of schizophrenia that includes primary and enduring negative symptoms. This study aimed to compare the differences in cognitive functioning and plasma levels of C-reactive protein (CRP) and ...
Dandan Wang   +8 more
doaj   +1 more source

Unseen Affective Faces Influence Person Perception Judgments in Schizophrenia. [PDF]

open access: yes, 2014
To demonstrate the influence of unconscious affective processing on consciously processed information among people with and without schizophrenia, we used a continuous flash suppression (CFS) paradigm to examine whether early and rapid processing of ...
Barrett, Lisa Feldman   +2 more
core   +1 more source

Rethinking Schizophrenia in the Context of Normal Neurodevelopment

open access: yesFrontiers in Cellular Neuroscience, 2013
The schizophrenia brain is differentiated from the normal brain by subtle changes, with significant overlap in measures between normal and disease states. For the past 25 years, schizophrenia has increasingly been considered a neurodevelopmental disorder.
Vibeke Sorensen Catts   +39 more
doaj   +1 more source

Cannabidiol versus risperidone for treatment of recent-onset psychosis with comorbid cannabis use: study protocol for a randomized controlled clinical trial

open access: yesBMC Psychiatry, 2021
Background Cannabis use is an important risk factor for development of psychosis and further transition to schizophrenia. The prevalence of patients with psychosis and comorbid cannabis use (dual diagnosis) is rising with no approved specialized ...
Jesper Østrup Rasmussen   +4 more
doaj   +1 more source

Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies. [PDF]

open access: yes, 2018
AimThe hippocampus is considered a key region in schizophrenia pathophysiology, but the nature of hippocampal subregion abnormalities and how they contribute to disease expression remain to be fully determined.
Matsumoto, Mitsuyuki   +2 more
core   +1 more source

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