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Schizophrenia [PDF]

open access: yesThe Lancet, 2016
Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. Dysfunction of dopaminergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points to a widespread and variable involvement ...
A. Vita   +4 more
semanticscholar   +9 more sources

Schizophrenia [PDF]

open access: yesNature Reviews Disease Primers, 2015
Schizophrenia is a chronic psychiatric disorder with a heterogeneous genetic and neurobiological background that influences early brain development, and is expressed as a combination of psychotic symptoms - such as hallucinations, delusions and disorganization - and motivational and cognitive dysfunctions.
René S Kahn   +2 more
exaly   +6 more sources

Nonsocial and social cognition in schizophrenia: current evidence and future directions

open access: yesWorld Psychiatry, 2019
Cognitive impairment in schizophrenia involves a broad array of nonsocial and social cognitive domains. It is a core feature of the illness, and one with substantial implications for treatment and prognosis.
Michael F Green, Junghee Lee
exaly   +2 more sources

Schizophrenia [PDF]

open access: yesNew England Journal of Medicine, 2019
Stephen R Marder, Tyrone D Cannon
exaly   +5 more sources

Motor deficits in schizophrenia quantified by nonlinear analysis of postural sway. [PDF]

open access: yes, 2012
Motor dysfunction is a consistently reported but understudied aspect of schizophrenia. Postural sway area was examined in individuals with schizophrenia under four conditions with different amounts of visual and proprioceptive feedback: eyes open or ...
Bolbecker, Amanda R.   +6 more
core   +22 more sources

Learnings from conducting mental health research during 2004 tsunami in Tamil Nadu, India

open access: yesBMC Public Health, 2020
Background The Indian Ocean tsunami experience in 2004 caused a major loss of life and subsequent emotional trauma for survivors. Psychosocial needs in the aftermath of this disaster were extensive, yet the cohesion and effectiveness of response were ...
R. Padmavati   +6 more
doaj   +1 more source

Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia

open access: yesMolecular Brain, 2021
Reductions in the GABAergic neurotransmitter system exist across multiple brain regions in schizophrenia and encompass both pre- and postsynaptic components.
Tertia D. Purves-Tyson   +4 more
doaj   +1 more source

Bullying among children and adolescents in the SAARC countries: A scoping review

open access: yesHeliyon, 2022
Background: Bullying is defined as repetitive and intentional aggression by an individual or group towards other individuals that happens in a power differential between the individuals being bullied and the bullies.
Shiva Prakash Srinivasan   +4 more
doaj   +1 more source

Cognitive and negative symptoms in schizophrenia with L‐Carnosine adjuvant therapy – A randomized double‐blind placebo‐controlled study

open access: yesPharmacology Research & Perspectives, 2023
The antioxidant L‐Carnosine is reported to improve negative and cognitive symptoms in Schizophrenia. A randomized double‐blind placebo‐controlled study was planned to study the effectiveness of adjuvant L‐Carnosine therapy in patients with Schizophrenia.
Hema Tharoor   +5 more
doaj   +1 more source

Mortality in people with schizophrenia: a systematic review and meta‐analysis of relative risk and aggravating or attenuating factors

open access: yesWorld Psychiatry, 2022
People with schizophrenia die 15‐20 years prematurely. Understanding mortality risk and aggravating/attenuating factors is essential to reduce this gap.
C. Correll   +10 more
semanticscholar   +1 more source

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