Results 31 to 40 of about 57,972 (301)

Psychotic symptoms in young adults exposed to childhood trauma - A 20 year follow-up study

, 2011
Childhood adversity has been shown to increase the risk of psychotic symptoms in adult life. However, there are no previous studies looking at the association between experiencing a natural disaster during childhood and the development of psychotic ...
McFarlane, A., Alexander McFarlane, Galletly, C., Van Hooff, M., Cherrie Galletly, Miranda Van Hooff   +5 more
core   +1 more source

Relationship between childhood trauma and psychotic symptoms in patients with 1 schizophrenia: A cross-sectional study

Psicosomática y Psiquiatría
Introduction: A complex interaction of both genetic and environmental factors causes schizophrenia. Childhood environment may interact with the social, behavioural, and cognitive antecedents of psychosis leading to mental illness in vulnerable population.
Raj Kumar Sahu, Anil Sisodia, Souvik Manna   +2 more
doaj   +1 more source

The Potential Relationship Between The Environmental Risk Factors And Social Cognition in Psychosis

European Psychiatry, 2022
Introduction In schizophrenia research, little is known about the relationship of environmental exposures with social cognition deficits. Objectives We aimed to investigate the relationship between social cognitive performance and well-defined ...
S. Cicek, F. Karadag
doaj   +1 more source

The educational implications of childhood onset schizophrenia [PDF]

, 2008
Includes bibliographical ...
Perreault, Kyle
core  

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Longitudinal metabolome profiling from pregnancy through childhood and risk of neurodevelopmental disorders at age 10

Nature Communications
Neurodevelopmental disorders (NDD) are characterized by impairments in brain development that affect motor and cognitive systems. Early identification of NDD risk factors is crucial for prevention.
Tingting Wang, Jens Richardt Møllegaard Jepsen, Rebecca Vinding, Nicklas Brustad, Liang Chen, María Hernández-Lorca, Mina Ali, Julie Bøjstrup Rosenberg, Parisa Mohammadzadeh, Michael Widdowson, Parvaneh Ebrahimi, Morten A. Rasmussen, Jonathan Thorsen, Klaus Bønnelykke, Bjørn H. Ebdrup, Bo Chawes   +15 more
doaj   +1 more source

Associations of Childhood Trauma Exposures with Depressive Symptoms and Moderating Effect of Resilience in Patients with Schizophrenia

Taiwanese Journal of Psychiatry
Objectives: Both depressive symptoms and childhood trauma exposures compromise mental health in patients with schizophrenia. In this cross-sectional study, we intended to examine the associations between various types of childhood trauma exposures and ...
Kuan-Lin Lee, Pei-Yu Chao, Chien-Wen Lin, Cheng-Fang Yen   +3 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Linking childhood trauma to the psychopathology of schizophrenia: the role of oxytocin

Schizophrenia
Childhood trauma has been linked to schizophrenia, but underlying biological mechanisms remain elusive. This study explored the potential role of plasma oxytocin as a mediator in the relationship between childhood trauma and the psychopathology of ...
Yuan-Jung Chen, Mong-Liang Lu, Yi-Hang Chiu, Chenyi Chen, Vitor Hugo Jesus Santos, Kah Kheng Goh   +5 more
doaj   +1 more source

Gene Expression Meta-Analysis of Cerebellum Samples Supports the FKBP5 Gene-Environment Interaction Model for Schizophrenia

Life, 2021
Background: One of the most studied molecular models of gene-environment interactions is that of FKBP5, which has been shown to interact with childhood adversity to increase the risk of psychiatric disorders, and has been implicated in schizophrenia ...
Libi Hertzberg, Ada H. Zohar, Assif Yitzhaky   +2 more
doaj   +1 more source