Results 51 to 60 of about 57,972 (301)

Impact of Childhood Adversity, as Early Life Distress, on Cytokine Alterations in Schizophrenia

Neuropsychiatric Disease and Treatment, 2023
Cedo Miljevic,1,2 Ana Munjiza-Jovanovic,1,3 Teodora Jovanovic4 1Department of Psychiatry, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 2Clinical Trial Unit, Institute of Mental Health, Belgrade, Serbia; 3Day Hospital for Adolescents ...
Miljevic C, Munjiza-Jovanovic A, Jovanovic T   +2 more
doaj  

Bleuler’s a or autism spectrum disorder in adults?

European Psychiatry, 2021
Introduction Nowadays we know that autism spectrum disorders (ASD) and Schizophrenic spectrum (SS) are different types of disorders in their etiology, symptoms and prognosis, but the clinical distinction is often difficult to make due to comorbidity ...
J. Miranda, L. Silva, C. Almeida, I. Figueiredo, D. Machado, S. Fonseca   +5 more
doaj   +1 more source

Pathways between childhood victimization and psychosis-like symptoms in the ALSPAC Birth Cohort [PDF]

, 2013
Background: Several large population-based studies have demonstrated associations between adverse childhood experiences and later development of psychotic symptoms.
Lewis, G., Maughan, B., Fisher, H. L., Lewis, Glyn, Fisher, Helen L; id_orcid, Schreier, Andrea, Lewis, Glyn H, Maughan, Barbara, Maughan, Barbara; id_orcid, Munafo, Marcus R., Wolke, D., Wolke, Dieter, Fisher, H., Zammit, Stanley, Munafò, Marcus R, Munafo, M. R., Schreier, A.   +16 more
core   +1 more source

Sleep Disturbances in Adults With Tuberous Sclerosis Complex: Influences of Treatment and Clinical Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Tuberous sclerosis complex (TSC) is a genetic condition with multisystem neurocutaneous signs, including hamartomas, epilepsy, and neuropsychological difficulties. Although sleep disorders are increasingly recognized in TSC, they remain poorly described in adults.
Kirstin A. Risgaard, Laura Farach, Hope Northrup, Sarah L. Wilson, Deborah Pearson, Syed Hashmi, Kate Richardson   +6 more
wiley   +1 more source

Association between childhood maltreatment and suicidal ideation among Chinese patients with chronic schizophrenia: the mediating role of insomnia

BJPsych Open
Background Childhood maltreatment is a well-established transdiagnostic risk factor for suicidal ideation; however, previous studies on their association in schizophrenia have produced highly varied results.
Yuzhu Hao, Pu Peng, Qianjin Wang, Yanan Zhou, Shubao Chen, Qiuxia Wu, Tieqiao Liu, Xiangyang Zhang   +7 more
doaj   +1 more source

Genome‐Wide Association Study of Symptom Change Following Cognitive Behavioral Therapy for Common Mental Disorders

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Cognitive behavioral therapy (CBT) is a well‐established, evidence‐based treatment for common mental disorders such as depression, anxiety disorders, and obsessive‐compulsive disorder (OCD). However, treatment outcomes vary widely, and a substantial proportion of patients do not achieve sufficient improvement.
Julia Bäckman, Olly Kravchenko, Matthew Halvorsen, Elles de Schipper, Ekaterina Ivanova, Viktor Kaldo, Nils Hentati Isacsson, Thorstein Olsen Eide, Kira D. Höffler, Manuel Mattheisen, Bjarne Hansen, Gerd Kvale, Kristen Hagen, Jan Haavik, David Mataix‐Cols, James J. Crowley, John Wallert, Christian Rück, Nordic OCD and Related Disorders Consortium (NORDiC), Julia Bäckman, Long‐Long Chen, James J. Crowley, Elles de Schipper, Diana Pascal, Jan Haavik, Kristen Hagen, Matthew W. Halvorsen, Bjarne Hansen, Kira D. Höffler, Fredrik Johansson, Anna K. Kähler, Elinor K. Karlsson, Gerd Kvale, Paul Lichtenstein, Kerstin Lindblad‐Toh, Manuel Mattheisen, David Mataix‐Cols, Kathleen Morrill, Christian Rück, Thorstein Olsen Eide, Nora I. Strom, John Wallert   +41 more
wiley   +1 more source

Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia

Neuropsychiatric Disease and Treatment, 2023
Mahmut Onur Karaytuğ,1 Lut Tamam,1 Mehmet Emin Demirkol,1 Zeynep Namlı,1 Mahmut Gürbüz,2 Caner Yeşiloğlu3 1Department of Psychiatry, Faculty of Medicine, Çukurova University, Adana, Turkey; 2Clinic for Psychiatry and ...
Karaytuğ MO, Tamam L, Demirkol ME, Namlı Z, Gürbüz M, Yeşiloğlu C   +5 more
doaj  

Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth

Genome Biology, 2023
Background Increased expression of the complement component 4A (C4A) gene is associated with a greater lifetime risk of schizophrenia. In the brain, C4A is involved in synaptic pruning; yet, it remains unclear the extent to which upregulation of C4A ...
Leanna M. Hernandez, Minsoo Kim, Pan Zhang, Richard A. I. Bethlehem, Gil Hoftman, Robert Loughnan, Diana Smith, Susan Y. Bookheimer, Chun Chieh Fan, Carrie E. Bearden, Wesley K. Thompson, Michael J. Gandal   +11 more
doaj   +1 more source

The impact of traumatic childhood events on functioning in patients with schizophrenia

European Psychiatry, 2022
Introduction A history of adverse childhood experiences (ACEs) can increase the risk of schizophrenia spectrum disorders and might be related to unfavorable clinical and functional outcomes of psychosis Objectives To assess the relationship between ...
C. Neily, N. Charfi, G. Smaoui, R. Feki, S. Omri, L. Zouari, J. Ben Thabet, M. Maâlejboauli, M. Maalej   +8 more
doaj   +1 more source

A Global Prospective Harmonization Framework for Suicidality, Anhedonia, and Obsessive‐Compulsive Symptoms in Psychiatric Genetic Studies: A Cross‐Continental Study Within the Ancestral Population Network

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT This study aims to prospectively collect harmonized, quantitative, and dimensional psychiatric phenotypes (suicidality, anhedonia, and obsessive‐compulsive symptoms) and information on discrimination, stigma, and unfair treatment in up to 27,500 individuals across diverse ancestries and clinical populations for genetic analysis within the NIMH
Ana M. Diaz‐Zuluaga, Jacey L. Anderberg, Ana M. Ramirez‐Diaz, Andrea Horvath Marques, Catherine E. Rast, Daniel Bustamante, Deborah Jonker, Johanna Valencia‐Echeverry, Joseph Kyebuzibwa, Josselyn S. Muñoz, Kristien van der Walt, Mauricio Castaño Ramirez, Olivia Wootton, Renee M. Frederick, Rocky E. Stroud II, Ruben Gur, Sang Jin Rhee, Shaili C. Jha, Stella Gichuru, Susan Service, Victor I. Reus, Akena Dickens, Carlos Lopez‐Jaramillo, Carrie E. Bearden, Dan J. Stein, Ezra S. Susser, James J. Crowley, Jonathan Flint, Kenneth S. Kendler, Lukoye Atwoli, Michele T. Pato, Nelson B. Freimer, Roel A. Ophoff, Yong Min Ahn, Loes Olde Loohuis, Eric A. Storch, Bizu Gelaye   +36 more
wiley   +1 more source