Results 71 to 80 of about 57,972 (301)

Linking Brain Morphometry to Psychometric Measures and Energy‐Metabolic Biomarkers in Adults With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is associated with differences in neurodevelopment and altered metabolism, yet the interplay between brain morphometry, mitochondrial and energy metabolism biomarkers, and autistic traits in adults remains poorly understood. This study investigates the link between brain structure, psychometric measures, and both
Eleonora Esposto, Kathrin Nickel, Dominique Endres, Kimon Runge, Katharina Domschke, Thomas Lange, Marco Reisert, Anke Schumann, Cinzia Niolu, Ludger Tebartz van Elst, Simon Maier   +10 more
wiley   +1 more source

Ventricular enlargement, neuropsychological status, and premorbid function in schizophrenia, [PDF]

, 1994
Ventricular enlargement is one of the most consistently documented neurobiological abnormalities in schizophrenia. The timing of the development of this abnormality in the course of schizophrenic illness and its relationship to neuropsychological ...
Meador-Woodruff, James H., Goldman, Robert S., Kim, Lorraine, McGrath-Giroux, Marlene, DeQuardo, John R., Tandon, Rajiv, Brunberg, James A.   +6 more
core   +1 more source

ACKR1/Duffy‐null genotype testing for clozapine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Clozapine is licenced for treatment‐resistant schizophrenia and psychosis in Parkinson's disease. In the United Kingdom, there is a mandatory requirement for absolute neutrophil count (ANC) and white blood cell count (WBC) monitoring to safeguard against agranulocytosis.
Stephen Murtough, Oriella Stellakis, Daisy Mills, Blanca Bjourson, Vicky Chaplin, Dharmisha Chauhan, Bev Chipp, Marius Cotic, Jana de Villiers, Olubanké Dzahini, Frances Elmslie, Katie Evans, Shreyans Gandhi, Dyfrig A. Hughes, Huajie Jin, Daniele Panconesi, Anna Skowronska, Sanjay M. Sisodiya, Ed Silva, Vicky Stinton, Sara Stuart‐Smith, Sarah Tarrant, David Taylor, Lauren Varney, James T. R. Walters, Michelle Wood, Jessica Woodley, Cinzia Dello Russo, Munir Pirmohamed, Elvira Bramon   +29 more
wiley   +1 more source

Navigating the bio-politics of childhood [PDF]

, 2011
Childhood research has long shared a bio-political terrain with state agencies in which children figure primarily as ‘human futures’. In the 20th century bio-social dualism helped to make that terrain navigable by researchers, but, as life processes ...
Nick Lee, Lee, Nicholas, Motzkau, J., Johanna Motzkau, Lee, Nick, Motzkau, Johanna   +5 more
core   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Effects of prenatal nutrient supplementation and early life exposures on neurodevelopment at age 10: a randomised controlled trial - the COPSYCH study protocol

BMJ Open, 2022
Henrik Larsson, Birgitte Fagerlund, Bjørn H Ebdrup, Klaus Bønnelykke, Christos Pantelis, Niels Bilenberg, Hans Bisgaard, Jakob Stokholm, Parisa Mohammadzadeh, Julie Bøjstrup Rosenberg, Rebecca Vinding, Jens Richardt Møllegaard Jepsen, Ulrich Lindberg, Nilo Følsgaard, Mikkel Erlang Sørensen, Daban Sulaiman, Jayachandra Mitta Raghava, Mark Vestergaard, Bo Chawes, Birte Yding Glenthøj   +19 more
doaj   +1 more source

The use of Clozapine in Adolescents: A Case Report

South African Journal of Psychiatry, 2011
This is a report about a child diagnosed with childhood-onset schizophrenia and subsequently treated with clozapine. Clozapine is often used as the last line of treatment for patients with schizophrenia even in the pediatric population.
Aili Hanim Hashim, Subash Kumar Pillai, Amer Siddiq Amer Nordin, Manveen Kaur   +3 more
doaj   +1 more source

Depression, Anxiety and Criminal Behaviour Between Ages 32 and 48: A Propensity Score Matching Analysis From the Cambridge Study in Delinquent Development

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background Depression, anxiety and criminal behaviour are often correlated, but the direction and nature of these associations remain contested. Aims To investigate the temporal relationships between depression and/or anxiety and criminal behaviour at age 32 and depression and/or anxiety and criminal behaviour at age 48.
Kim Reising, Maria M. Ttofi
wiley   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

The relationship of childhood bullying and paranoid thinking in a clinical population: the role of mediators

, 2012
A wealth of research evidence has been accumulating over the last two decades, highlighting the association of childhood trauma and psychosis. However, research has focused more on investigating the prevalence of childhood trauma in individuals with ...
Chaudhry, Khadija
core