Results 101 to 110 of about 921,979 (317)

Amyloban, extracted from Hericium erinaceus, ameliorates social deficits and suppresses the enhanced dopaminergic system in social defeat stress mice

Neuropsychopharmacology Reports
Social dysfunctions are common in various psychiatric disorders, including depression, schizophrenia, and autism, and are long‐lasting and difficult to treat.
Tianran Wang, Kazuya Toriumi, Kazuhiro Suzuki, Mitsuhiro Miyashita, Azuna Ozawa, Mayuko Masada, Masanari Itokawa, Makoto Arai   +7 more
doaj   +1 more source

A System for Differentiation of Schizophrenia and Bipolar Disorder based on rsfMRI [PDF]

arXiv, 2023
Schizophrenia and bipolar disorder are debilitating psychiatric illnesses that can be challenging to diagnose accurately. The similarities between the diseases make it difficult to differentiate between them using traditional diagnostic tools. Recently, resting-state functional magnetic resonance imaging (rsfMRI) has emerged as a promising tool for the
arxiv  

Inflammation in Schizophrenia: Pathogenetic Aspects and Therapeutic Considerations

Schizophrenia bulletin, 2018
This paper discusses the current evidence from animal and human studies for a central role of inflammation in schizophrenia. In animal models, pre- or perinatal elicitation of the immune response may increase immune reactivity throughout life, and ...
N. Müller
semanticscholar   +1 more source

Deep brain stimulation in schizophrenia [PDF]

, 2014
Deep brain stimulation (DBS) has successfully advanced treatment options of putative therapy-resistant neuropsychiatric diseases. Building on this strong foundation more and more mental disorders in the stadium of therapy-resistance are considered as ...
Bodatsch, M., Gruendler, T.O.J., Klosterkötter, J., Kuhn, J., Lenartz, D., Sturm, V., Uhlhaas, P.J., Winter, C.   +7 more
core  

Simultaneous effects on parvalbumin-positive interneuron and dopaminergic system development in a transgenic rat model for sporadic schizophrenia [PDF]

, 2016
To date, unequivocal neuroanatomical features have been demonstrated neither for sporadic nor for familial schizophrenia. Here, we investigated the neuroanatomical changes in a transgenic rat model for a subset of sporadic chronic mental illness (CMI ...
Bader, V, Bidmon, HJ, Chwiesko, C, Crum, WR, Hamburg, H, Kipar, A, Korth, C, Sauvage, M, Trossbach, SV, Vernon, AC   +9 more
core   +3 more sources

Quantifying word salad: The structural randomness of verbal reports predicts negative symptoms and Schizophrenia diagnosis 6 months later [PDF]

arXiv, 2016
Background: The precise quantification of negative symptoms is necessary to improve differential diagnosis and prognosis prediction in Schizophrenia. In chronic psychotic patients, the representation of verbal reports as word graphs provides automated sorting of schizophrenia, bipolar disorder and control groups based on the degree of speech ...
arxiv  

Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in schizophrenia [PDF]

, 2010
of poster presentation shown at the 2nd Biennial Schizophrenia International Research Conference on Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in ...
Dawson, Neil, Higham, Des, Morris, Brian, Pratt, Judith   +3 more
core   +1 more source

No Effects of Cognitive Remediation on Cerebral White Matter in Individuals at Ultra-High Risk for Psychosis—A Randomized Clinical Trial

Frontiers in Psychiatry, 2020
BackgroundIndividuals at ultra-high risk for psychosis (UHR) present with subtle alterations in cerebral white matter (WM), which appear to be associated with clinical and functional outcome.
Tina D. Kristensen, Tina D. Kristensen, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Carsten Hjorthøj, Carsten Hjorthøj, René C. W. Mandl, René C. W. Mandl, Jayachandra M. Raghava, Jayachandra M. Raghava, Jens Richardt M. Jepsen, Jens Richardt M. Jepsen, Birgitte Fagerlund, Birgitte Fagerlund, Louise B. Glenthøj, Louise B. Glenthøj, Christina Wenneberg, Christina Wenneberg, Kristine Krakauer, Christos Pantelis, Christos Pantelis, Birte Y. Glenthøj, Birte Y. Glenthøj, Merete Nordentoft, Merete Nordentoft, Merete Nordentoft   +26 more
doaj   +1 more source

Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging

Scientific Reports, 2022
The generation of new neurons within the mammalian forebrain continues throughout life within two main neurogenic niches, the subgranular zone (SGZ) of the hippocampal dentate gyrus, and the subependymal zone (SEZ) lining the lateral ventricles.
Mainá Bitar, Christin Weissleder, Hayley F. North, Misaki S. Clearwater, Oressia Zalucki, Glenda M. Halliday, Maree J. Webster, Michael Piper, Cynthia Shannon Weickert, Guy Barry   +9 more
doaj   +1 more source

Predictive Linguistic Features of Schizophrenia [PDF]

Proceedings of the 6th Joint Conference on Lexical and Computational Semantics (*SEM 2017), Association for Computational Linguistics, 2017, pp. 241-250, 2018
Schizophrenia is one of the most disabling and difficult to treat of all human medical/health conditions, ranking in the top ten causes of disability worldwide. It has been a puzzle in part due to difficulty in identifying its basic, fundamental components.
arxiv