Morbidity burden and community-based palliative care are associated with rates of hospital use by people with schizophrenia in the last year of life: A population-based matched cohort study [PDF]
, 2018 Objective: People with schizophrenia face an increased risk of premature death from chronic diseases and injury. This study describes the trajectory of acute care health service use in the last year of life for people with schizophrenia and how this ...
Arendts, Glenn +4 more
core +5 more sources
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 192, Issue 1-2, Page 3-12, January-March 2023., 2023 Abstract Ubiquitous associations have been detected between different types of childhood psychopathology and polygenic risk scores based on adult psychiatric disorders and related adult outcomes, indicating that genetic factors partly explain the association between childhood psychopathology and adult outcomes. However, these analyses in general do not
Wonuola A. Akingbuwa +12 more
wiley +1 more source
Journal of Neuroinflammation, 2020 Background High inflammation status despite an absence of known infection characterizes a subpopulation of people with schizophrenia who suffer from more severe cognitive deficits, less cortical grey matter, and worse neuropathology. Transcripts encoding
Caitlin E. Murphy +7 more
doaj +1 more source
Craniofacial dysmorphology in 22q11.2 deletion syndrome by 3D laser surface imaging and geometric morphometrics: illuminating the developmental relationship to risk for psychosis [PDF]
, 2015 Persons with 22q11.2 deletion syndrome (22q11.2DS) are characterized inter alia by facial dysmorphology and greatly increased risk for psychotic illness. Recent studies indicate facial dysmorphology in adults with schizophrenia.
Aggarwal +58 more
core +1 more source
Journal of Neuroinflammation, 2017 Background Increases in pro-inflammatory cytokines are found in the brain and blood of people with schizophrenia. However, increased cytokines are not evident in all people with schizophrenia, but are found in a subset.
Danny Boerrigter +11 more
doaj +1 more source
Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies. [PDF]
, 2018 AimThe hippocampus is considered a key region in schizophrenia pathophysiology, but the nature of hippocampal subregion abnormalities and how they contribute to disease expression remain to be fully determined.
Matsumoto, Mitsuyuki +2 more
core +1 more source
Rethinking Schizophrenia in the Context of Normal Neurodevelopment
Frontiers in Cellular Neuroscience, 2013 The schizophrenia brain is differentiated from the normal brain by subtle changes, with significant overlap in measures between normal and disease states. For the past 25 years, schizophrenia has increasingly been considered a neurodevelopmental disorder.
Vibeke Sorensen Catts +39 more
doaj +1 more source
Increased Macrophages and C1qA, C3, C4 Transcripts in the Midbrain of People With Schizophrenia
Frontiers in Immunology, 2020 Increased cytokine and inflammatory-related transcripts are found in the ventral midbrain, a dopamine neuron-rich region associated with schizophrenia symptoms.
Tertia D. Purves-Tyson +12 more
doaj +1 more source
Schizophrenia research under the framework of predictive coding: body, language, and others [PDF]
arXiv, 2023 Although there have been so many studies on schizophrenia under the framework of predictive coding, works focusing on treatment are very preliminary. A model-oriented, operationalist, and comprehensive understanding of schizophrenia would promote the therapy turn of further research. We summarize predictive coding models of embodiment, co-occurrence of
arxiv
Abnormal Task Modulation of Oscillatory Neural Activity in Schizophrenia
Frontiers in Psychology, 2013 Schizophrenia patients have deficits in cognitive function that are a core feature of the disorder. AX-CPT is commonly used to study cognition in schizophrenia, and patients have characteristic pattern of behavioral and ERP response.
Elisa C Dias +6 more
doaj +1 more source