Results 31 to 40 of about 620,945 (334)

Increased Macrophages and C1qA, C3, C4 Transcripts in the Midbrain of People With Schizophrenia

Frontiers in Immunology, 2020
Increased cytokine and inflammatory-related transcripts are found in the ventral midbrain, a dopamine neuron-rich region associated with schizophrenia symptoms.
Tertia D. Purves-Tyson, Tertia D. Purves-Tyson, Kate Robinson, Amelia M. Brown, Danny Boerrigter, Helen Q. Cai, Helen Q. Cai, Christin Weissleder, Samantha J. Owens, Debora A. Rothmond, Cynthia Shannon Weickert, Cynthia Shannon Weickert, Cynthia Shannon Weickert   +12 more
doaj   +1 more source

Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia

medRxiv, 2020
Schizophrenia is a psychiatric disorder whose pathophysiology is largely unknown. It has a heritability of 60-80%, much of which is attributable to common risk alleles, suggesting genome-wide association studies can inform our understanding of aetiology.
S. Ripke, J. Walters, M. O’Donovan
semanticscholar   +1 more source

Abnormal Task Modulation of Oscillatory Neural Activity in Schizophrenia

Frontiers in Psychology, 2013
Schizophrenia patients have deficits in cognitive function that are a core feature of the disorder. AX-CPT is commonly used to study cognition in schizophrenia, and patients have characteristic pattern of behavioral and ERP response.
Elisa C Dias, Stephan eBickel, Michael L Epstein, Pejman eSehatpour, Pejman eSehatpour, Daniel C Javitt, Daniel C Javitt   +6 more
doaj   +1 more source

Reward Processing as an Indicator of Vulnerability or Compensatory Resilience in Psychoses? Results From a Twin Study

Biological Psychiatry Global Open Science, 2023
Background: Findings of reward disturbances in unaffected relatives of patients with schizophrenia suggest reward disturbances as an endophenotype for schizophrenia.
Mette Ødegaard Nielsen, Egill Rostrup, Rikke Hilker, Christian Legind, Simon Anhøj, Trevor William Robbins, Barbara J. Sahakian, Birgitte Fagerlund, Birte Glenthøj   +8 more
doaj   +1 more source

The COVID-19 Global Pandemic: Implications for People With Schizophrenia and Related Disorders

Schizophrenia bulletin, 2020
The coronavirus disease-19 (COVID-19) global pandemic has already had an unprecedented impact on populations around the world, and is anticipated to have a disproportionate burden on people with schizophrenia and related disorders.
Nicole Kozloff, B. Mulsant, V. Stergiopoulos, A. Voineskos   +3 more
semanticscholar   +1 more source

Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment

Translational Psychiatry, 2021
We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B6 (VB6) in peripheral blood than do healthy controls. In a previous study, we found that VB6 level was inversely proportional to the patient’s positive and
Kazuya Toriumi, Mitsuhiro Miyashita, Kazuhiro Suzuki, Nao Yamasaki, Misako Yasumura, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Noriyoshi Usui, Masanari Itokawa, Makoto Arai   +10 more
doaj   +1 more source

SCHIZOPHRENIA

, 2023
This article provides detailed information about schizophrenia. In particular, the following article provides detailed information on the causes of schizophrenia, diagnosis methods, and treatment measures for this disease.
openaire   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Effectiveness of Virtual - Compensatory Cognitive Training (V-CCT) for improving cognition in persons with schizophrenia - a multi- centre randomized controlled trial

Trials
Background Cognitive deficits are the core component in persons with schizophrenia which impacts their socio-occupational functioning. Also, cognitive deficits cause significant impairment with the person’s quality of life [3].
Sonia Sims, Suvarna Jyothi Kantipudi, Yogitha Ashok, B. Nisha, Subhashini Gopal, Elsa Joseph, S. Amritha, Lakshmi Venkatraman, Pratiksha Venkatasubramanian, Padmavati Ramachandran   +9 more
doaj   +1 more source

Schizophrenia and the eye

Schizophrenia Research: Cognition, 2015
Although visual processing impairments are common in schizophrenia, it is not clear to what extent these originate in the eye vs. the brain. This review highlights potential contributions, from the retina and other structures of the eye, tovisual processing impairments in schizophrenia and high-risk states.
Richard B Rosen, Steven M. Silverstein
openaire   +4 more sources