Results 81 to 90 of about 693,791 (276)

A System for Differentiation of Schizophrenia and Bipolar Disorder based on rsfMRI [PDF]

arXiv, 2023
Schizophrenia and bipolar disorder are debilitating psychiatric illnesses that can be challenging to diagnose accurately. The similarities between the diseases make it difficult to differentiate between them using traditional diagnostic tools. Recently, resting-state functional magnetic resonance imaging (rsfMRI) has emerged as a promising tool for the
arxiv  

Deep brain stimulation in schizophrenia [PDF]

, 2014
Deep brain stimulation (DBS) has successfully advanced treatment options of putative therapy-resistant neuropsychiatric diseases. Building on this strong foundation more and more mental disorders in the stadium of therapy-resistance are considered as ...
Bodatsch, M., Gruendler, T.O.J., Klosterkötter, J., Kuhn, J., Lenartz, D., Sturm, V., Uhlhaas, P.J., Winter, C.   +7 more
core  

Simultaneous effects on parvalbumin-positive interneuron and dopaminergic system development in a transgenic rat model for sporadic schizophrenia [PDF]

, 2016
To date, unequivocal neuroanatomical features have been demonstrated neither for sporadic nor for familial schizophrenia. Here, we investigated the neuroanatomical changes in a transgenic rat model for a subset of sporadic chronic mental illness (CMI ...
Bader, V, Bidmon, HJ, Chwiesko, C, Crum, WR, Hamburg, H, Kipar, A, Korth, C, Sauvage, M, Trossbach, SV, Vernon, AC   +9 more
core   +3 more sources

Quantifying word salad: The structural randomness of verbal reports predicts negative symptoms and Schizophrenia diagnosis 6 months later [PDF]

arXiv, 2016
Background: The precise quantification of negative symptoms is necessary to improve differential diagnosis and prognosis prediction in Schizophrenia. In chronic psychotic patients, the representation of verbal reports as word graphs provides automated sorting of schizophrenia, bipolar disorder and control groups based on the degree of speech ...
arxiv  

Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in schizophrenia [PDF]

, 2010
of poster presentation shown at the 2nd Biennial Schizophrenia International Research Conference on Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in ...
Dawson, Neil, Higham, Des, Morris, Brian, Pratt, Judith   +3 more
core   +1 more source

No Effects of Cognitive Remediation on Cerebral White Matter in Individuals at Ultra-High Risk for Psychosis—A Randomized Clinical Trial

Frontiers in Psychiatry, 2020
BackgroundIndividuals at ultra-high risk for psychosis (UHR) present with subtle alterations in cerebral white matter (WM), which appear to be associated with clinical and functional outcome.
Tina D. Kristensen, Tina D. Kristensen, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Carsten Hjorthøj, Carsten Hjorthøj, René C. W. Mandl, René C. W. Mandl, Jayachandra M. Raghava, Jayachandra M. Raghava, Jens Richardt M. Jepsen, Jens Richardt M. Jepsen, Birgitte Fagerlund, Birgitte Fagerlund, Louise B. Glenthøj, Louise B. Glenthøj, Christina Wenneberg, Christina Wenneberg, Kristine Krakauer, Christos Pantelis, Christos Pantelis, Birte Y. Glenthøj, Birte Y. Glenthøj, Merete Nordentoft, Merete Nordentoft, Merete Nordentoft   +26 more
doaj   +1 more source

Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging

Scientific Reports, 2022
The generation of new neurons within the mammalian forebrain continues throughout life within two main neurogenic niches, the subgranular zone (SGZ) of the hippocampal dentate gyrus, and the subependymal zone (SEZ) lining the lateral ventricles.
Mainá Bitar, Christin Weissleder, Hayley F. North, Misaki S. Clearwater, Oressia Zalucki, Glenda M. Halliday, Maree J. Webster, Michael Piper, Cynthia Shannon Weickert, Guy Barry   +9 more
doaj   +1 more source

Predictive Linguistic Features of Schizophrenia [PDF]

Proceedings of the 6th Joint Conference on Lexical and Computational Semantics (*SEM 2017), Association for Computational Linguistics, 2017, pp. 241-250, 2018
Schizophrenia is one of the most disabling and difficult to treat of all human medical/health conditions, ranking in the top ten causes of disability worldwide. It has been a puzzle in part due to difficulty in identifying its basic, fundamental components.
arxiv  

Reward Processing as an Indicator of Vulnerability or Compensatory Resilience in Psychoses? Results From a Twin Study

Biological Psychiatry Global Open Science, 2023
Background: Findings of reward disturbances in unaffected relatives of patients with schizophrenia suggest reward disturbances as an endophenotype for schizophrenia.
Mette Ødegaard Nielsen, Egill Rostrup, Rikke Hilker, Christian Legind, Simon Anhøj, Trevor William Robbins, Barbara J. Sahakian, Birgitte Fagerlund, Birte Glenthøj   +8 more
doaj  

Brain MRI-based 3D Convolutional Neural Networks for Classification of Schizophrenia and Controls [PDF]

arXiv, 2020
Convolutional Neural Network (CNN) has been successfully applied on classification of both natural images and medical images but not yet been applied to differentiating patients with schizophrenia from healthy controls. Given the subtle, mixed, and sparsely distributed brain atrophy patterns of schizophrenia, the capability of automatic feature ...
arxiv