Results 61 to 70 of about 77,423 (292)
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Explaining lengths and shapes of yeast by scaling arguments. [PDF]
PLoS ONE, 2009 Lengths and shapes are approached in different ways in different fields: they serve as a read-out for classifying genes or proteins in cell biology whereas they result from scaling arguments in condensed matter physics.
Daniel Riveline
doaj +1 more source
Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates [PDF]
, 2013 Nonhomologous end-joining (NHEJ) pathways repair DNA double-strand breaks (DSBs) in eukaryotes and many prokaryotes, although it is not reported to operate in the third domain of life, archaea. Here, we describe a complete NHEJ complex, consisting of DNA
Bartlett, Edward +2 more
core +1 more source
An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System
Genetics, 2015 The fission yeast Schizosaccharomyces pombe is an important model organism for the study of eukaryotic molecular and cellular biology. Studies of S. pombe, together with studies of its distant cousin, Saccharomyces cerevisiae, have led to the discovery ...
C. S. Hoffman, V. Wood, P. Fantes
semanticscholar +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
HIV-1 Protease in the Fission Yeast Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2016 BACKGROUND:HIV-1 protease (PR) is an essential viral enzyme. Its primary function is to proteolyze the viral Gag-Pol polyprotein for production of viral enzymes and structural proteins and for maturation of infectious viral particles. Increasing evidence
Zsigmond Benko +4 more
doaj +1 more source
Silver nanoparticles elevate mutagenesis of eukaryotic genomes
G3: Genes, Genomes, Genetics, 2023 Metal nanoparticles, especially silver, have been used in various medical scenarios, due to their excellent antimicrobial effects. Recent studies have shown that AgNPs do not exert mutagenic effects on target bacteria, but the degree to which they ...
Kun Wu +7 more
doaj +1 more source
Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage [PDF]
, 1994 The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction.
Al-Harithy, R +6 more
core +1 more source
Insect Science, EarlyView.Abstract The Sterile Insect Technique (SIT) is an environmentally friendly, sustainable pest control approach, which uses large‐scale releases of sterile insects to suppress or eradicate target populations through infertile matings. The efficiency of SIT is enhanced by male‐only releases requiring genetic sexing strains (GSSs) that are classically ...
Chun Yin Leung +2 more
wiley +1 more source
Tellurite Reduction in Schizosaccharomyces pombe [PDF]
Journal of General Microbiology, 1974 SUMMARY: The fission yeast Schizosaccharomyces pombe was grown in the presence of 10-3 to 10-6 M-sodium tellurite. Growth was inhibited by tellurite and at concentrations above 10-5 M a black reduction product (probably tellurium) was visible in sedimented cells.
openaire +2 more sources