Results 91 to 100 of about 61,932 (214)

Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates [PDF]

, 2013
Nonhomologous end-joining (NHEJ) pathways repair DNA double-strand breaks (DSBs) in eukaryotes and many prokaryotes, although it is not reported to operate in the third domain of life, archaea. Here, we describe a complete NHEJ complex, consisting of DNA
Bartlett, Edward, Brissett, Nigel C, Doherty, Aidan J   +2 more
core   +1 more source

Tandem inactivation of inositol pyrophosphatases Asp1, Siw14, and Aps1 illuminates functional redundancies in inositol pyrophosphate catabolism in fission yeast

mBio
Inositol pyrophosphates 5-IP7, 1-IP7, and 1,5-IP8 are eukaryal signaling molecules that influence cell physiology, especially phosphate homeostasis. In fission yeast, 1,5-IP8 and 1-IP7 impact gene expression by acting as agonists of RNA 3'-processing and
Beate Schwer, Isabel Prucker, Ana M. Sanchez, Jill Babor, Henning J. Jessen, Stewart Shuman   +5 more
doaj   +1 more source

Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition [PDF]

, 2013
Previously we identified Rrp1 and Rrp2 as two proteins required for the Sfr1/Swi5-dependent branch of homologous recombination (HR) in Schizosaccharomyces pombe.
Ahn, Akamatsu, Akamatsu, Akamatsu, Antony M. Carr, Cal-Bąkowska, Caspari, Craven, Doe, Doe, Dorota Dziadkowiec, Dupaigne, Dziadkowiec, Feng, Gareau, Haruta, Hecker, Hope, Hope, Ira, Jensen, Jia, Karol Kramarz, Karolina Kanik, Khasanov, Krogh, Kurokawa, Lambert, Lambert, Liu, Liu, Liu, Lorenz, Mankouri, McGlynn, Miyabe, Moreno, Morishita, Mullen, Mullen, Murray, New, Osman, Osterman, Piotr Wiśniewski, Prakash, Prudden, Raji, Rijkers, Say, Sebesta, Shinohara, Shinohara, Stewart, Sun, Sun, Sun, Sung, Symington, Thacker, Tsubouchi, Tsutsui, Uzunova, Win, Yuan   +64 more
core   +1 more source

New cassettes for single-step drug-resistance and prototrophic marker switching in fission yeast [PDF]

, 2015
Copyright © 2015 John Wiley & Sons, Ltd. Funded by College of Life Science and Medicine, University of Aberdeen, UK This work was funded by a start-up grant from the College of Life Science and Medicine, University of Aberdeen, UK.
Lorenz, Alexander
core   +1 more source

Engineering ER-stress dependent non-conventional mRNA splicing

eLife, 2018
The endoplasmic reticulum (ER) protein folding capacity is balanced with the protein folding burden to prevent accumulation of un- or misfolded proteins.
Weihan Li, Voytek Okreglak, Jirka Peschek, Philipp Kimmig, Meghan Zubradt, Jonathan S Weissman, Peter Walter   +6 more
doaj   +1 more source

Importin α and vNEBD Control Meiotic Spindle Disassembly in Fission Yeast

Cell Reports, 2018
Summary: In metazoans, the nuclear envelope (NE) breakdown (NEBD) occurs during “open” mitosis and meiosis. In the fission yeast Schizosaccharomyces pombe, the mitosis and the first meiotic division (MI) are “closed,” during which the NE is maintained ...
Ignacio Flor-Parra, Ana Belén Iglesias-Romero, Silvia Salas-Pino, Rafael Lucena, Juan Jimenez, Rafael R. Daga   +5 more
doaj   +1 more source

Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.

PLoS ONE, 2019
L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong, Hyeonseok Jin, Jeong Ho Chang   +2 more
doaj   +1 more source

TORC1-Dependent Phosphorylation Targets in Fission Yeast

Biomolecules, 2017
Target of rapamycin (TOR) kinase controls cell metabolism and growth in response to environmental cues such as nutrients, growth factors, and stress. TOR kinase is widely conserved across eukaryotes.
Yoko Otsubo, Akio Nakashima, Masayuki Yamamoto, Akira Yamashita   +3 more
doaj   +1 more source

Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae

BMC Research Notes, 2018
Objective N-terminal acetylation is a common protein modification that occurs preferentially co-translationally as the substrate N-terminus is emerging from the ribosome.
Sylvia Varland, Thomas Arnesen
doaj   +1 more source

Methionine Induces Sexual Development in the Fission Yeast Schizosaccharomyces pombe via an ste11 -Dependent Signalling Pathway [PDF]

, 1998
Anne‐Marie Schweingruber, Norma Hilti, Eleonore Edenharter, M. Ernst Schweingruber   +3 more
openalex   +1 more source