Systematic analysis reveals the prevalence and principles of bypassable gene essentiality
An essential gene may become non-essential when another gene is mutated. Here, the authors investigate this type of digenic interaction, termed ‘bypass of essentiality’, in the fission yeast Schizosaccharomyces pombe, and show that bypassable essential ...
Jun Li +10 more
doaj +1 more source
Population genomics of the fission yeast Schizosaccharomyces pombe. [PDF]
The fission yeast Schizosaccharomyces pombe has been widely used as a model eukaryote to study a diverse range of biological processes. However, population genetic studies of this species have been limited to date, and we know very little about the ...
Jeffrey A Fawcett +10 more
doaj +1 more source
In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells. [PDF]
To investigate the mechanisms of spindle elongation and chromosome separation in the fission yeast Schizosaccharomyces pombe, we have developed an in vitro assay using a temperature-sensitive mutant strain, nuc2.
Cande, WZ +3 more
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Antimicrobial activities of marine fungi from Malaysia [PDF]
Copyright 2011 Elsevier B.V., All rights reserved.Peer reviewedPublisher ...
Alias, S.A. +6 more
core +1 more source
Perspectives for Advancing Biotechnological Succinic Acid Production
Succinic acid is an important molecule for sustainable chemical manufacturing, but its industrial production faces high costs and sustainability challenges, which are linked to feedstocks and excessive acid/base consumption. This opinion explores production routes based on next‐generation feedstocks and low‐pH fermentations to inspire novel cost ...
Christoph Gunkel, Bastian Blombach
wiley +1 more source
CRL4Wdr70 regulates H2B monoubiquitination and facilitates Exo1-dependent resection
The repair of double-strand DNA breaks by homologous recombination requires resection of the DNA ends. Here the authors show that in Schizosaccharomyces pombe and human cells, Wdr70 is recruited as part of the CRL4 complex to promote ubiquitination of ...
Ming Zeng +12 more
doaj +1 more source
Isolation and characterisation of Sri Lankan yeast germplasm and its evaluation for alcohol production [PDF]
Use of inferior yeast cultures represents one of the reasons for low fermentation efficiencies in Sri Lankan alcohol distilleries that use sugarcane molasses. The present study isolated and characterised yeast strains found in natural environments in Sri
Chandrasena, G. +2 more
core +3 more sources
Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging
This study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Yanzhuo Kong +7 more
wiley +1 more source
DNA Preparation from Schizosaccharomyces pombe [PDF]
This protocol includes two methods for genomic DNA preparation from Schizosaccharomyces pombe. The first is a quick method for preparation of DNA suitable for polymerase chain reaction (PCR) genotyping. The second, longer method yields high-quality DNA that can be used for amplification of targeting cassettes.
Assen, Roguev +2 more
openaire +2 more sources
Genetic Requirements for Intra-Chromosomal Deletions [PDF]
Chromosomal deletions are one of the most dangerous types of DNA damage and often arise as a result of inappropriately repaired DNA double strand breaks (DSB).
McPherson, Matthew
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