Results 21 to 30 of about 61,932 (214)

The Rad4TopBP1 ATR-Activation domain functions in G1/S phase in a chromatin-dependent manner [PDF]

, 2012
DNA damage checkpoint activation can be subdivided in two steps: initial activation and signal amplification. The events distinguishing these two phases and their genetic determinants remain obscure.
Carr, Antony, Caspari, Thomas, Chahwan, Charly, Garcia, Valerie, Lin, Su-Jiun, Miyabe, Izumi, Morishita, Takashi, Schmidt, Ulrike, Wardlaw, Christopher Paul   +8 more
core   +9 more sources

Extensive mass spectrometry-based analysis of the fission yeast proteome: the Schizosaccharomyces pombe PeptideAtlas [PDF]

, 2013
We report a high quality and system-wide proteome catalogue covering 71% (3,542 proteins) of the predicted genes of fission yeast, Schizosaccharomyces pombe, presenting the largest protein dataset to date for this important model organism.
Aebersold, Alexa, Anderson, Baerenfaller, Beck, Benjamini, Beyer, Bitton, Brockmann, Brunner, Chen, Craig, Davis, de Godoy, de Graaf, Deutsch, Deutsch, Elias, Geer, Ghaemmaghami, Greenbaum, Gygi, Humphrey, Huttlin, Ishihama, Ishihama, Keller, Kuster, Lackner, Lackner, Lam, Lam, Lam, Lam, Marguerat, Mata, Nagaraj, Nesvizhskii, Perkins, Reiter, Remacle, Sakharkar, Savas, Schmidt, Schmidt, Schrimpf, Sherwood, Shevchenko, Shteynberg, Sipiczki, Vizcaíno, Warringer, Wilhelm, Wood, Wood, Wood, Wu, Zhang   +57 more
core   +1 more source

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original ...
Lorenz, Alexander, Mehats, Alizée, Osman, Fekret, Whitby, Matthew C   +3 more
core   +1 more source

Gene expression profiling data of Schizosaccharomyces pombe under nitrosative stress using differential display

Data in Brief, 2016
Excess production of nitric oxide (NO) and reactive nitrogen intermediates (RNIs) causes nitrosative stress on cells. Schizosaccharomyces pombe was used as a model to study nitrosative stress response.
Pranjal Biswas, Uddalak Majumdar, Sanjay Ghosh   +2 more
doaj   +1 more source

The regional sequestration of heterochromatin structural proteins is critical to form and maintain silent chromatin

Epigenetics & Chromatin, 2022
Budding yeast Saccharomyces cerevisiae and fission yeast Schizosaccharomyces pombe are good models for heterochromatin study. In S. pombe, H3K9 methylation and Swi6, an ortholog of mammalian HP1, lead to heterochromatin formation. However, S.
Junsoo Oh, Soojin Yeom, Jiyeon Park, Jung-Shin Lee   +3 more
doaj   +1 more source

Sulfide-quinone oxidoreductase is required for cysteine synthesis and indispensable to mitochondrial health

Redox Biology, 2021
Mitochondrial dysfunction is related to common age-related disorders, including neurodegenerative diseases, metabolic syndrome, and carcinogenesis. Therefore, maintaining the functionality and integrity of mitochondria is important for human health ...
Xi Zhang, Yuping Xin, Zhigang Chen, Yongzhen Xia, Luying Xun, Huaiwei Liu   +5 more
doaj   +1 more source

The role of Schizosaccharomyces pombe SUMO ligases in genome stability [PDF]

, 2007
SUMOylation is a post-translational modification that affects a large number of proteins, many of which are nuclear. While the role of SUMOylation is beginning to be elucidated, it is clear that understanding the mechanisms that regulate the process is ...
A. Skilton, al-Khodairy, Allshire, Allshire, Andrews, Apionishev, Branzei, Chakrabarti, Cheng, E.A. Outwin, Ekwall, F.-X. Ogi, F.Z. Watts, Grishchuk, Ho, Ho, Hoege, Hooker, J.C.-Y. Ho, Johnson, Kagey, Kahyo, L. Gardner, L.K. Boyd, M.A.M. Trickey, McDonald, Okubo, Pichler, Potts, Reindle, Sachdev, Schmidt, Sergeant, Shayeghi, Shin, Stelter, Strahl-Bolsinger, Tanaka, Taylor, Thon, Watts, Xhemalce, Xhemalce, Zhao, Zhao   +44 more
core   +2 more sources

Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels

eLife, 2020
Cytokinesis, which enables the physical separation of daughter cells once mitosis has been completed, is executed in fungal and animal cells by a contractile actin- and myosin-based ring (CAR).
Elisa Gómez-Gil, Rebeca Martín-García, Jero Vicente-Soler, Alejandro Franco, Beatriz Vázquez-Marín, Francisco Prieto-Ruiz, Teresa Soto, Pilar Pérez, Marisa Madrid, Jose Cansado   +9 more
doaj   +1 more source

Distinct requirements for the Rad32(Mre¹¹) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA [PDF]

, 2009
For a cancer cell to resist treatment with drugs that trap topoisomerases covalently on the DNA, the topoisomerase must be removed. In this study, we provide evidence that the Schizosaccharomyces pombe Rad32Mre11 nuclease activity is involved in the ...
Akamatsu, Antony M. Carr, Baldwin, Champoux, Connelly, Connelly, Edgar Hartsuiker, El-Khamisy, Farah, Gutz, Hartsuiker, Hopfner, Hopfner, Keeney, Keeney, Krogh, Krogh, Lengsfeld, Limbo, Liu, Malik, Matthew J. Neale, McKee, Miyoshi, Moreau, Neale, Nitiss, Osheroff, Porter, Pouliot, Prinz, Sartori, Shaw, Stracker, Subramanian, Takashima, Tomita, Utsugi, Young   +38 more
core   +2 more sources

Désadification biologique des vins par les levures de fleur

OENO One, 1971
L'utilisation par les bactéries ou les levures de certains acides organiques présents dans le vin est un procédé biologique qui offre un grand intérêt pour l'élimination totale ou partielle de certains acides, comme l'acide malique ou l'acide acétique ...
C. LLAGUNO, M.J. FERNANDEZ, M.D. GARRIDO, J. GARRIDO   +3 more
doaj   +1 more source