Results 61 to 70 of about 33,254 (223)

Computational systems biology approaches to cellular aging—Integrating network maps and dynamical models

open access: yesQuantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cellular aging is a multifaceted complex process. Many genes and factors have been identified that regulate cellular aging. However, how these genes and factors interact with one another and how these interactions drive the aging processes in single cells remain largely unclear.
Hetian Su, Nan Hao
wiley   +1 more source

From Yeast to Therapeutics: Modeling Neurodegenerative Diseases in Saccharomyces cerevisiae

open access: yesYeast, Volume 42, Issue 12, Page 283-302, December 2025.
Yeast plasmids expressing human Aβ‐42, α‐syn, htt, and TDP‐43. Their fate includes an equilibrium between the endocytic pathway and aggregates that potentially disrupt endocytosis, vesicular transport, vacuolar autophagy, and mitochondrial activity. ABSTRACT Here, we review the use of Saccharomyces cerevisiae as a powerful model organism for studying ...
Jose Ribamar Ferreira‐Junior   +2 more
wiley   +1 more source

Asymmetric inheritance of cytoophidia in Schizosaccharomyces pombe

open access: yesBiology Open, 2014
A general view is that Schizosaccharomyces pombe undergoes symmetric cell division with two daughter cells inheriting equal shares of the content from the mother cell.
Jing Zhang, Lydia Hulme, Ji-Long Liu
doaj   +1 more source

The Power of Yeast

open access: yesYeast, Volume 42, Issue 12, Page 303-310, December 2025.
ABSTRACT Yeasts have been intimately connected with human civilization for millennia, originally used for fermentation in food and beverage production. This article explores the multifaceted roles of yeasts—particularly Saccharomyces cerevisiae—as both a model organism and a cell factory.
Jens Nielsen
wiley   +1 more source

Whole‐Genome Sequencing and Phenotyping Reveal Specific Adaptations of Lachancea thermotolerans to the Winemaking Environment

open access: yesMolecular Ecology, Volume 34, Issue 24, December 2025.
ABSTRACT Adaptation to the environment plays an essential role in yeast evolution as a consequence of selective pressures. Lachancea thermotolerans, a yeast related to fermentation and one of the current trends in wine technology research, has undergone an anthropisation process, leading to a notable genomic and phenomic differentiation.
Javier Vicente   +5 more
wiley   +1 more source

Mitotic mapping ofSchizosaccharomyces pombe [PDF]

open access: yesGenetical Research, 1970
SUMMARYGenetic mapping by means of mitotic haploidization (induced by parafluoropkenylalanine) and mitotic crossing-over was carried out with the fission yeastSchizosaccharomyces pombe. Thirty-two different genetic markers were involved in this investigation; some meiotic linkage relationships had been previously reported (Leupold, Megnet) for 16 of ...
openaire   +2 more sources

Characterization of Schizosaccharomyces pombe RNA triphosphatase [PDF]

open access: yesNucleic Acids Research, 2001
RNA triphosphatase catalyzes the first step in mRNA cap formation which entails the cleavage of the beta-gamma phosphoanhydride bond of triphosphate-terminated RNA to yield a diphosphate end that is then capped with GMP by RNA guanylyltransferase.
Y, Pei   +3 more
openaire   +2 more sources

DNA Aptamers Targeting BcSOD1: A Novel Strategy for Controlling Botrytis cinerea in Sustainable Agriculture

open access: yesPlant Biotechnology Journal, Volume 23, Issue 12, Page 5778-5796, December 2025.
ABSTRACT Botrytis cinerea, the necrotrophic fungus responsible for grey mould disease, is a major threat to global crop production. Control strategies mainly rely on chemical fungicides, but resistance development limits their long‐term effectiveness. This study introduces, for the first time in crop protection, the use of DNA aptamers as a novel and ...
Alba López‐Laguna   +9 more
wiley   +1 more source

The Combined Use of Schizosaccharomyces pombe and Lachancea thermotolerans—Effect on the Anthocyanin Wine Composition

open access: yesMolecules, 2017
The most popular methodology to make red wine is through the combined use of Saccharomyces cerevisiae yeast and lactic acid bacteria, for alcoholic fermentation and malolactic fermentation respectively.
Ángel Benito   +2 more
doaj   +1 more source

Mitotic Phosphorylation of Swi6/HP1 Regulates Its Chromatin Binding and Chromosome Segregation

open access: yesThe FASEB Journal, Volume 39, Issue 21, 15 November 2025.
Heterochromatin protein 1 (HP1) plays an important role in heterochromatin assembly. HP1 proteins undergo additional phosphorylation during mitosis. However, the functional significance of the mitotic phosphorylation of HP1 remains unclear. We identified mitotic phosphorylation sites within fission yeast Swi6 and showed that this phosphorylation is ...
Yuriko Yoshimura   +8 more
wiley   +1 more source

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