Results 71 to 80 of about 61,932 (214)

Ectopic A-lattice seams destabilize microtubules [PDF]

, 2014
Natural microtubules typically include one A-lattice seam within an otherwise helically symmetric B-lattice tube. It is currently unclear how A-lattice seams influence microtubule dynamic instability.
A des Georges, A Desai, A Dimitrov, A Grafmuller, AA Hyman, B Vitre, D Chretien, D Chretien, D Chretien, D Chretien, D Panda, D Sept, DJ Odde, DN Drechsel, DP Dias, DR Drummond, E Nogales, EM Mandelkow, EM Mandelkow, FM Coquelle, G Brouhard, G Margolin, H Bowne-Anderson, H Sui, IM Crevel, JG Cueva, JL Hoog, JR McIntosh, JR Simon, JS Kaye, KE Busch, L Amos, L Sandblad, LG Tilney, LM Rice, M Braun, M Caplow, M Caplow, M Katsuki, M Katsuki, M Kikkawa, MK Gardner, MK Gardner, N Galjart, P Bieling, R Dallai, RA Walker, RA Walker, SP Maurer, SP Maurer, T Mitchison, T Mitchison, Y Komarova, YH Song, ZC Zhu   +54 more
core   +1 more source

DNA Aptamers Targeting BcSOD1: A Novel Strategy for Controlling Botrytis cinerea in Sustainable Agriculture

Plant Biotechnology Journal, Volume 23, Issue 12, Page 5778-5796, December 2025.
ABSTRACT Botrytis cinerea, the necrotrophic fungus responsible for grey mould disease, is a major threat to global crop production. Control strategies mainly rely on chemical fungicides, but resistance development limits their long‐term effectiveness. This study introduces, for the first time in crop protection, the use of DNA aptamers as a novel and ...
Alba López‐Laguna, Álvaro Polonio, Lucía Jiménez‐Castro, Yandira Morales, Alejandra Vielba‐Fernández, M. Elena Martín, Víctor M. González, Antonio de Vicente, Alejandro Pérez‐García, Dolores Fernández‐Ortuño   +9 more
wiley   +1 more source

Checkpoint-Dependent Regulation of Origin Firing and Replication Fork Movement in Response to DNA Damage in Fission Yeast [PDF]

, 2009
To elucidate the checkpoint mechanism responsible for slowing passage through S phase when fission yeast cells are treated with the DNA-damaging agent methyl methanesulfonate (MMS), we carried out two-dimensional gel analyses of replication intermediates
Huberman, Joel A., Kumar, Sanjay
core   +3 more sources

Mitotic Phosphorylation of Swi6/HP1 Regulates Its Chromatin Binding and Chromosome Segregation

The FASEB Journal, Volume 39, Issue 21, 15 November 2025.
Heterochromatin protein 1 (HP1) plays an important role in heterochromatin assembly. HP1 proteins undergo additional phosphorylation during mitosis. However, the functional significance of the mitotic phosphorylation of HP1 remains unclear. We identified mitotic phosphorylation sites within fission yeast Swi6 and showed that this phosphorylation is ...
Yuriko Yoshimura, Aki Hayashi, Mayo Tanaka, Mieko Suzuki‐Matsubara, Reiko Nakagawa, Gohei Nishibuchi, Hideaki Tagami, Masaya Oki, Jun‐ichi Nakayama   +8 more
wiley   +1 more source

Using canavanine resistance to measure mutation rates in Schizosaccharomyces pombe [PDF]

, 2022
Chen‐Chun Pai, Ellen Heitzer, Sibyl Bertrand, Sophia Toumazou, Timothy C. Humphrey, Stephen Kearsey   +5 more
openalex   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

The Combined Use of Schizosaccharomyces pombe and Lachancea thermotolerans—Effect on the Anthocyanin Wine Composition

Molecules, 2017
The most popular methodology to make red wine is through the combined use of Saccharomyces cerevisiae yeast and lactic acid bacteria, for alcoholic fermentation and malolactic fermentation respectively.
Ángel Benito, Fernando Calderón, Santiago Benito   +2 more
doaj   +1 more source

Centromeric Sequences in Ogataea polymorpha Genome Enable Development of Stable Multigene Expression Plasmid Tools

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The centromeric sequences of Ogataea polymorpha, a methylotrophic non‐conventional yeast, were characterised for the first time and support the development of new genetically stable centromeric plasmids with high genetic stability and compatibility, providing powerful genetic toolboxes for the synthetic biology and metabolic engineering‐driven ...
Yanfei Cheng, Yuanyuan Shi, Ning Sun, Xin Zhang, Mengwei Sun, Xiuping He   +5 more
wiley   +1 more source

Combinatorial Analyses of Pre‐mRNA Splicing‐Defective Mutants Reveal Differential Quantitative Requirements for Shelterin in Distinct Telomere Functions

Genes to Cells, Volume 30, Issue 6, November 2025.
Different telomere functions show distinct dependence on Rap1 protein levels revealed by analyses of pre‐mRNA splicing mutants. ABSTRACT Telomeres perform multiple functions to maintain genome stability, including telomere length regulation, chromosome end protection, and meiotic chromosome dynamics.
Miho Takeuchi, Yoko Otsubo, Junko Kanoh
wiley   +1 more source

Comparative Genomic Analysis of Co‐Occurring Hybrid Zones of House Mouse Parasites Pneumocystis murina and Syphacia obvelata Using Genome Polarisation

Molecular Ecology, Volume 34, Issue 21, November 2025.
ABSTRACT Parasites are expected to hybridise in similar ways to free‐living organisms, although this may be modified by their reduced genome architecture. Recombinant strains and taxa of hybrid origin can be studied in nature where hosts come into secondary contact. Here we apply genome‐wide analysis to parasites from a contact previously characterised
Jan Petružela, Beate Nürnberger, Alexis Ribas, Georgios Koutsovoulos, Dagmar Čížková, Alena Fornůsková, Tatiana Aghová, Mark Blaxter, Joëlle Goüy de Bellocq, Stuart J. E. Baird   +9 more
wiley   +1 more source