Results 71 to 80 of about 33,254 (223)

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Centromeric Sequences in Ogataea polymorpha Genome Enable Development of Stable Multigene Expression Plasmid Tools

open access: yesMicrobial Biotechnology, Volume 18, Issue 11, November 2025.
The centromeric sequences of Ogataea polymorpha, a methylotrophic non‐conventional yeast, were characterised for the first time and support the development of new genetically stable centromeric plasmids with high genetic stability and compatibility, providing powerful genetic toolboxes for the synthetic biology and metabolic engineering‐driven ...
Yanfei Cheng   +5 more
wiley   +1 more source

Conflicting phylogenetic position of Schizosaccharomyces pombe

open access: yesGenomics, 2006
The phylogenetic position of the fission yeast Schizosaccharomyces pombe in the fungal Tree of Life is still controversial. Three alternative phylogenetic positions have been proposed in the literature, namely (1) a position basal to the Hemiascomycetes and Euascomycetes, (2) a position as a sister group to the Euascomycetes with the Hemiascomycetes as
Kuramae, E.E.   +3 more
openaire   +4 more sources

Extending the Schizosaccharomyces pombe molecular genetic toolbox.

open access: yesPLoS ONE, 2014
Targeted alteration of the genome lies at the heart of the exploitation of S. pombe as a model system. The rate of analysis is often determined by the efficiency with which a target locus can be manipulated.
Dorota Fennessy   +11 more
doaj   +1 more source

Using canavanine resistance to measure mutation rates in Schizosaccharomyces pombe [PDF]

open access: gold, 2022
Chen‐Chun Pai   +5 more
openalex   +1 more source

Tandem inactivation of inositol pyrophosphatases Asp1, Siw14, and Aps1 illuminates functional redundancies in inositol pyrophosphate catabolism in fission yeast

open access: yesmBio
Inositol pyrophosphates 5-IP7, 1-IP7, and 1,5-IP8 are eukaryal signaling molecules that influence cell physiology, especially phosphate homeostasis. In fission yeast, 1,5-IP8 and 1-IP7 impact gene expression by acting as agonists of RNA 3'-processing and
Beate Schwer   +5 more
doaj   +1 more source

Importin α and vNEBD Control Meiotic Spindle Disassembly in Fission Yeast

open access: yesCell Reports, 2018
Summary: In metazoans, the nuclear envelope (NE) breakdown (NEBD) occurs during “open” mitosis and meiosis. In the fission yeast Schizosaccharomyces pombe, the mitosis and the first meiotic division (MI) are “closed,” during which the NE is maintained ...
Ignacio Flor-Parra   +5 more
doaj   +1 more source

Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.

open access: yesPLoS ONE, 2019
L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong   +2 more
doaj   +1 more source

Engineering ER-stress dependent non-conventional mRNA splicing

open access: yeseLife, 2018
The endoplasmic reticulum (ER) protein folding capacity is balanced with the protein folding burden to prevent accumulation of un- or misfolded proteins.
Weihan Li   +6 more
doaj   +1 more source

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