Results 71 to 80 of about 74,140 (300)
Role for the fission yeast RecQ helicase in DNA repair in G2. [PDF]
Members of the RecQ helicase subfamily are mutated in several human genomic instability syndromes, such as Bloom, Werner, and Rothmund-Thomson syndromes. We show that Rqh1, the single Schizosaccharomyces pombe homologue, is a 3'-to-5' helicase and exists
Ampatzidou, Eleni+3 more
core +3 more sources
Objectives The fission yeast Schizosaccharomyces pombe is predicted to encode ~ 200 proteins of
Sophie Longmuir+2 more
doaj +1 more source
Explaining lengths and shapes of yeast by scaling arguments. [PDF]
Lengths and shapes are approached in different ways in different fields: they serve as a read-out for classifying genes or proteins in cell biology whereas they result from scaling arguments in condensed matter physics.
Daniel Riveline
doaj +1 more source
Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original ...
Lorenz, Alexander+3 more
core +1 more source
Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe.
This article discusses the advances made in epigenetic research using the model organism fission yeast Schizosaccharomyces pombe. S. pombe has been used for epigenetic research since the discovery of position effect variegation (PEV).
R. Allshire, K. Ekwall
semanticscholar +1 more source
Methionine as an antimutagen in Schizosaccharomyces pombe [PDF]
Methionine inhibition of the phenotypic expression of adn - → adn + reverse mutations in the fission yeast Schizosaccharomyces pombe was investigated. This inhibition occurred solely with L-methionine, and not with a variety of other growth factors. The inhibitory effect on revertant expression did not apply to a number of reverse and forward mutations
openaire +2 more sources
Systematic analysis reveals the prevalence and principles of bypassable gene essentiality
An essential gene may become non-essential when another gene is mutated. Here, the authors investigate this type of digenic interaction, termed ‘bypass of essentiality’, in the fission yeast Schizosaccharomyces pombe, and show that bypassable essential ...
Jun Li+10 more
doaj +1 more source
Physical mechanisms influencing life origin and development. Physical-biochemical paradigm of Life [PDF]
The present view of biological phenomena is based on a biochemical paradigm that development of living organisms is defined by information stored in a molecular form as some genetic code. However, new discoveries indicate that biological phenomena cannot be confined to a biochemical realm alone, but are also influenced by physical mechanisms.
arxiv +1 more source
DNA repair, DNA replication and human disorders: A personal journey [PDF]
I was born in 1946 and grew up in the industrial north-west of England close to the city of Manchester. My parents were German- Jewish refugees, who left Germany fairly early, in 1933.
Alan R. Lehmann+75 more
core +1 more source
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker+7 more
wiley +1 more source