Results 71 to 80 of about 33,254 (223)
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
The centromeric sequences of Ogataea polymorpha, a methylotrophic non‐conventional yeast, were characterised for the first time and support the development of new genetically stable centromeric plasmids with high genetic stability and compatibility, providing powerful genetic toolboxes for the synthetic biology and metabolic engineering‐driven ...
Yanfei Cheng +5 more
wiley +1 more source
Conflicting phylogenetic position of Schizosaccharomyces pombe
The phylogenetic position of the fission yeast Schizosaccharomyces pombe in the fungal Tree of Life is still controversial. Three alternative phylogenetic positions have been proposed in the literature, namely (1) a position basal to the Hemiascomycetes and Euascomycetes, (2) a position as a sister group to the Euascomycetes with the Hemiascomycetes as
Kuramae, E.E. +3 more
openaire +4 more sources
Extending the Schizosaccharomyces pombe molecular genetic toolbox.
Targeted alteration of the genome lies at the heart of the exploitation of S. pombe as a model system. The rate of analysis is often determined by the efficiency with which a target locus can be manipulated.
Dorota Fennessy +11 more
doaj +1 more source
Using canavanine resistance to measure mutation rates in Schizosaccharomyces pombe [PDF]
Chen‐Chun Pai +5 more
openalex +1 more source
Inositol pyrophosphates 5-IP7, 1-IP7, and 1,5-IP8 are eukaryal signaling molecules that influence cell physiology, especially phosphate homeostasis. In fission yeast, 1,5-IP8 and 1-IP7 impact gene expression by acting as agonists of RNA 3'-processing and
Beate Schwer +5 more
doaj +1 more source
Importin α and vNEBD Control Meiotic Spindle Disassembly in Fission Yeast
Summary: In metazoans, the nuclear envelope (NE) breakdown (NEBD) occurs during “open” mitosis and meiosis. In the fission yeast Schizosaccharomyces pombe, the mitosis and the first meiotic division (MI) are “closed,” during which the NE is maintained ...
Ignacio Flor-Parra +5 more
doaj +1 more source
Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.
L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong +2 more
doaj +1 more source
Engineering ER-stress dependent non-conventional mRNA splicing
The endoplasmic reticulum (ER) protein folding capacity is balanced with the protein folding burden to prevent accumulation of un- or misfolded proteins.
Weihan Li +6 more
doaj +1 more source

