Results 111 to 120 of about 56,119 (295)

Virtual Identification of Essential Proteins Within the Protein Interaction Network of Yeast [PDF]

, 2005
Topological analysis of large scale protein-protein interaction networks (PINs) is important for understanding the organisational and functional principles of individual proteins. The number of interactions that a protein has in a PIN has been observed to be correlated with its indispensability.
arxiv   +1 more source

Distinct requirements for the Rad32(Mre¹¹) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA [PDF]

, 2009
For a cancer cell to resist treatment with drugs that trap topoisomerases covalently on the DNA, the topoisomerase must be removed. In this study, we provide evidence that the Schizosaccharomyces pombe Rad32Mre11 nuclease activity is involved in the ...
Akamatsu, Antony M. Carr, Baldwin, Champoux, Connelly, Connelly, Edgar Hartsuiker, El-Khamisy, Farah, Gutz, Hartsuiker, Hopfner, Hopfner, Keeney, Keeney, Krogh, Krogh, Lengsfeld, Limbo, Liu, Malik, Matthew J. Neale, McKee, Miyoshi, Moreau, Neale, Nitiss, Osheroff, Porter, Pouliot, Prinz, Sartori, Shaw, Stracker, Subramanian, Takashima, Tomita, Utsugi, Young   +38 more
core   +2 more sources

Algal and Fungal Antioxidants Alleviate Oxidative Stress‐Induced Reproductive Defects

Food Science &Nutrition, Volume 13, Issue 5, May 2025.
In the in vivo models, fungi and/or algae‐derived metabolites (polysaccharides, carotenoids, ergothioneine, phycobiliproteins, phlorotannins, and cordycepin) correct the impaired reproductive functions in males and/or females by increasing antioxidant enzyme activities, decreasing oxidative stress, inflammation, and apoptosis, alleviating ovarian and ...
Nazli Pinar Arslan, Seyda Albayrak, Aysenur Budak‐Savas, Ahmet Hacimuftuoglu, Tugba Orak, Aysenur Ozdemir, Omer Karadagoglu, Sevval Yildirim, Handan Cinar‐Yilmaz, Mesut Taskin   +9 more
wiley   +1 more source

Characterization of Schizosaccharomyces pombe Copper Transporter Proteins in Meiotic and Sporulating Cells [PDF]

Journal of Biological Chemistry, 2014
Meiosis requires copper to undertake its program in which haploid gametes are produced from diploid precursor cells. In Schizosaccharomyces pombe, copper is transported by three members of the copper transporter (Ctr) family, namely Ctr4, Ctr5, and Ctr6.
Raphaël Ioannoni, Simon Labbé, Jude Beaudoin, Samuel Plante   +3 more
openaire   +3 more sources

Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation

Cell Reports, 2020
Summary: Heterochromatin functions as a scaffold for factors responsible for gene silencing and chromosome segregation. Heterochromatin can be assembled by multiple pathways, including RNAi and RNA surveillance.
Si Young Lee, Stevephen Hung, Caroline Esnault, Rakesh Pathak, Kory R. Johnson, Oluwadamilola Bankole, Akira Yamashita, Hongen Zhang, Henry L. Levin   +8 more
doaj  

Length, Protein-Protein Interactions, and Complexity [PDF]

, 2004
The evolutionary reason for the increase in gene length from archaea to prokaryotes to eukaryotes observed in large scale genome sequencing efforts has been unclear. We propose here that the increasing complexity of protein-protein interactions has driven the selection of longer proteins, as longer proteins are more able to distinguish among a larger ...
arxiv   +1 more source

Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA [PDF]

, 2015
SMC5/6 is a highly conserved protein complex related to cohesin and condensin, which are the key components of higher-order chromatin structures. The SMC5/6 complex is essential for proliferation in yeast and is involved in replication fork stability and
Adamus, Marek, Alt, Aaron, Jurcisinova, Lenka, Lehmann, Alan R, Liao, Chunyan, Novakova, Marketa, Oliver, Antony W, Palecek, Jan J, Skoupilova, Hana, Vondrova, Lucie, Zabrady, Katerina   +10 more
core   +2 more sources

Production of yeast cell wall polysaccharides‐β‐glucan and chitin by using food waste substrates: Biosynthesis, production, extraction, and purification methods

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 3, May 2025.
Abstract Food waste causes significant environmental and economic challenges worldwide, prompting many nations to prioritize its reduction and recycling. As a nutrient‐rich material containing vitamins, proteins, and carbohydrates, it serves as a promising substrate for the cultivation of single‐cell microorganisms like yeast.
Deniz Günal‐Köroğlu, Gulsah Karabulut, Fariddudin Mohammadian, Aslı Can Karaca, Esra Capanoglu, Tuba Esatbeyoglu   +5 more
wiley   +1 more source

Vesicle-mediated Protein Transport Pathways to the Vacuole in Schizosaccharomyces pombe

Cell Structure and Function, 2003
The vacuole of Saccharomyces cerevisiae plays essential roles not only for osmoregulation and ion homeostasis but also down-regulation (degradation) of cell surface proteins and protein and organellar turnover. Genetic selections and genome-wide screens in S.
Yasuko Fujita, Akira Hosomi, Naotaka Tanaka, Tomoko Iwaki, Kaoru Takegawa, Tomotake Morita   +5 more
openaire   +4 more sources

Inhibition of Protein Translocation in Permeabilized Cells ofSchizosaccharomyces pombeby Puromycin [PDF]

Bioscience, Biotechnology, and Biochemistry, 1992
To investigate protein translocation in eukaryotes, we reconstituted a protein translocation system using the permeabilized spheroplasts (P-cells) of the fission yeast Schizosaccharomyces pombe. The precursor of a sex pheromone of Saccharomyces cerevisiae, prepro-alpha-factor, was translocated across the endoplasmic reticulum (ER) of S.
Koji Yoda, Hideko Kambe-Honjoh, Makari Yamasaki   +2 more
openaire   +3 more sources