Results 131 to 140 of about 56,119 (295)

The extent of error-prone replication-restart by homologous recombination is controlled by Exo1 and checkpoint proteins [PDF]

, 2014
Genetic instability, a hallmark of cancer, can occur when the replication machinery encounters a barrier. The intra-S phase checkpoint maintains stalled replication forks in a replication-competent configuration by phosphorylating replisome components ...
Ahn, Alabert, Bailis, Barlow, Bastia, Bester, Biswas, Boddy, Bolderson, Brown, Bähler, Carr, Carr, Casper, Cha, Chen, Cobb, Cobb, Codlin, Cotta-Ramusino, Dalgaard, De Piccoli, Durkin, El-Shemerly, Errico, Eydmann, Froget, Haghnazari, Halazonetis, Hartsuiker, Heichinger, Hu, Iraqui, Jia, Kai, Kaochar, Katou, Kolodner, Koundrioukoff, Krejci, Lambert, Lambert, Lambert, Lambert, Lambert, Lambert, Lee, Lindsay, Lisby, Lopes, Lucca, Maundrell, Meister, Mimitou, Miyabe, Miyabe, Mizuno, Mizuno, Moreau, Moreau, Moreno, Morin, Myung, Myung, Pandita, Raynard, Sabatinos, Segurado, Segurado, Smolka, Sogo, Stracker, Sun, Symington, Sørensen, Tercero, Tsubouchi, Watson, Zhu, Zou, Zubko   +80 more
core   +2 more sources

Engineering of nicotianamine synthesis enhances cadmium mobility in plants and results in higher seed cadmium concentrations

The Plant Journal, Volume 122, Issue 2, April 2025.
SUMMARY Efficient biofortification, i.e., the enrichment of edible plant organs with micronutrients available for human consumption, is pursued through breeding and genetic engineering approaches. Enriching for iron (Fe) and zinc (Zn), two of the most critical trace elements, in cereal grains can be achieved by boosting the synthesis of nicotianamine ...
Fabian Hollmann, Michael Weber, Mark G. M. Aarts, Stephan Clemens   +3 more
wiley   +1 more source

Nuclear Envelope Proteins Modulating the Heterochromatin Formation and Functions in Fission Yeast

Cells, 2020
The nuclear envelope (NE) consists of the inner and outer nuclear membranes (INM and ONM), and the nuclear pore complex (NPC), which penetrates the double membrane. ONM continues with the endoplasmic reticulum (ER).
Yasuhiro Hirano, Haruhiko Asakawa, Takeshi Sakuno, Tokuko Haraguchi, Yasushi Hiraoka   +4 more
doaj   +1 more source

Π-cyc: A Reference-free SNP Discovery Application using Parallel Graph Search [PDF]

arXiv, 2018
Motivation: Working with a large number of genomes simultaneously is of great interest in genetic population and comparative genomics research. Bubbles discovery in multi-genomes coloured de bruijn graph for de novo genome assembly is a problem that can be translated to cycles enumeration in graph theory.
arxiv  

Impact of Kombucha Fermentation on the Flavor and Physicochemical Properties of Tea (Camellia sinensis) Flower Infusions

Food Frontiers, Volume 6, Issue 2, Page 750-762, March 2025.
Kombucha fermentation significantly improved the flavor of tea flowers. Both volatile and non‐volatile components changed substantially during the process. ABSTRACT Tea (Camellia sinensis) flower is a nutritious and affordable raw material for beverages.
Leyu Wang, Panjie Sun, Mengxin Huang, Ziyi Han, Haonan Yu, Kaixi Wang, Junsheng Liu, Yuanyuan Wu, Puming He, Youying Tu, Bo Li   +10 more
wiley   +1 more source

Isolation of protein glycosylation mutants in the fission yeast Schizosaccharomyces pombe.

Molecular Biology of the Cell, 1995
We have isolated mutants in the fission yeast Schizosaccharomyces pombe that are defective in protein glycosylation. A collection of osmotically sensitive mutants was prepared and screened for glycosylation defects using lectin staining as an assay. Mutants singly defective in four glycoprotein synthesis genes (gps1-4) were isolated, all of which bind
Martin D. Snider, Kristen M. Huang
openaire   +4 more sources

Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe [PDF]

, 2010
Nonsense-mediated mRNA decay (NMD) is a translation-linked process that destroys mRNAs with premature translation termination codons (PTCs). In mammalian cells, NMD is also linked to pre-mRNA splicing, usually PTCs trigger strong NMD only when positioned
Carter MS, Culbertson MR, Hodgkin J, Jikai Wen, Le Hir H, Muhlemann O, Peltz SW, Saverio Brogna, Zhang J, Zhang SA   +9 more
core   +3 more sources

Pichia pastoris Fep1 is a [2Fe-2S] protein with a Zn finger that displays an unusual oxygen-dependent role in cluster binding [PDF]

, 2016
Fep1, the iron-responsive GATA factor from the methylotrophic yeast Pichia pastoris, has been characterised both in vivo and in vitro. This protein has two Cys(2)-Cys(2) type zinc fingers and a set of four conserved cysteines arranged in a Cys-X-5-Cys-X ...
Battistoni, Andrea, BONACCORSI DI PATTI, Maria Carmela, Cutone, Antimo, Giorgi, Alessandra, Howes, Barry D., Miele, Adriana Erica, Miele, Rossella, Musci, Giovanni, Smulevich, Giulietta   +8 more
core   +3 more sources

In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells. [PDF]

, 1990
To investigate the mechanisms of spindle elongation and chromosome separation in the fission yeast Schizosaccharomyces pombe, we have developed an in vitro assay using a temperature-sensitive mutant strain, nuc2.
Cande, WZ, Hirano, T, Masuda, H, Yanagida, M   +3 more
core  

Recombinant expression and domain structure of the Rna1 protein from Schizosaccharomyces pombe

FEBS Letters, 1995
The amino acid sequence of Rna1p, a yeast protein implicated in the maturation and/or nucleocytoplasmic transport of RNA, is characterised by the presence of eight leucine‐rich repeats (LLRs) as well as two intervening repeats of a different type and a highly acidic C‐terminal region.
Jörg Haberland, Volker Gerke
openaire   +3 more sources