Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy [PDF]
, 2014 Development of single-molecule localization microscopy techniques has allowed nanometre scale localization accuracy inside cells, permitting the resolution of ultra-fine cell structure and the elucidation of crucial molecular mechanisms.
Adam T. Watson +46 more
core +1 more source
DNA damage repair proteins across the Tree of Life
iScience, 2023 Summary: Genome maintenance is orchestrated by a highly regulated DNA damage response with specific DNA repair pathways. Here, we investigate the phylogenetic diversity in the recognition and repair of three well-established DNA lesions, primarily ...
Emily Nischwitz +8 more
doaj
Using the DHFR Heat-Inducible Degron for Protein Inactivation in Schizosaccharomyces pombe
, 2009 Inactivating a specific protein in vivo can yield important information about its function. One strategy previously developed in Saccharomyces cerevisiae by the Varshavsky group involves fusing a degron, derived from mouse dihydrofolate reductase, to the N-terminus of the target protein, which thereby confers temperature-sensitive degradation at the ...
Kearsey, S, Gregan, J
openaire +4 more sources
The Schizosaccharomyces pombe mam2 gene encodes a putative pheromone receptor which has a significant homology with the Saccharomyces cerevisiae Ste2 protein. [PDF]
, 1991 Kenji Kitamura, Chikashi Shimoda
openalex +1 more source
Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombe. [PDF]
, 1994 Kazuhiro Shiozaki +3 more
openalex +1 more source
Biology Open, 2014 The Tsc1–Tsc2 complex homologous to human tuberous sclerosis complex proteins governs amino acid uptake by regulating the expression and intracellular distribution of amino acid transporters in Schizosaccharomyces pombe.
Akio Nakashima +3 more
doaj +1 more source
Global protein function prediction in protein-protein interaction networks [PDF]
Nature Biotech. 21, 697-700 (2003), 2003 The determination of protein functions is one of the most challenging problems of the post-genomic era. The sequencing of entire genomes and the possibility to access gene's co-expression patterns has moved the attention from the study of single proteins or small complexes to that of the entire proteome. In this context, the search for reliable methods
arxiv
Concerted action of RAS and G proteins in the sexual response pathways of Schizosaccharomyces pombe [PDF]
, 1994 Haopeng Xu +3 more
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Identification of two mismatch-binding activities in protein extracts of Schizosaccharomyces pombe [PDF]
, 1994 Oliver Fleck, Primo Schaär, Jürg Kohli
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Nonlinear memory in cell division dynamics across species [PDF]
arXivRegulation of cell growth and division is essential to achieve cell-size homeostasis. Recent advances in imaging technologies, such as ``mother machines" for bacteria or yeast, have allowed long-term tracking of cell-size dynamics across many generations, and thus have brought major insights into the mechanisms underlying cell-size control.
arxiv