Results 81 to 90 of about 31,402,141 (256)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Pilot evaluation of a school-based health education intervention in the UK: Facts4Life [PDF]

, 2017
© The Author 2017. Background This study assessed short-term changes in children’s health and illness attitudes and health status following Facts4Life, a school-based health education intervention.
Oliver, B., Bird, Emma L.
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Improving the school food environment and dietary intake of Dutch primary school students through the provision of a healthy school lunch: results of a pre-posttest effectiveness study

BMC Medicine
Background This study aimed to improve the school food environment and dietary intake of Dutch primary school students by providing a healthy school lunch. We investigated (1) how the school lunch affected dietary intake and students’ preferences for the
Sanne Coosje Dijkstra, Frédérique C. Rongen, Ellen van Kleef, Meeke Ummels, Lothar Kuiper, Jacob C. Seidell, Monique H. Vingerhoeds   +6 more
doaj   +1 more source

Reducing aggression and peer victimization in elementary classrooms: efficacy of the meet up and buddy up interventions

Frontiers in Developmental Psychology
The current study evaluated the efficacy of the Meet Up Buddy Up (MUBU) intervention, designed to promote positive classroom relationships among diverse groups of peers, in reducing aggression and peer victimization among 4th-grade students, with a focus
Ashley R. McDonald, Haining Ren, Sabina Low, Sabina Low, Laura D. Hanish, Laura D. Hanish, Richard A. Fabes, Richard A. Fabes, Carol Lynn Martin, Carol Lynn Martin, Cindy Faith Miller, Lorey A. Wheeler   +11 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

School nurse–delivered anxiety interventions for adolescents: a systematic review and meta-analysis

Cogent Psychology
Anxiety disorders among adolescents are common. Anxiety impacts social development, academic functioning, and overall well-being. To address the need for early and accessible interventions, there is growing interest in school nurses’ potential to deliver
Ingrid Osland, Åshild Tellefsen Haaland, Joe Himle, Thomas Bjerregaard Bertelsen   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Whole-school mental health promotion in Australia [PDF]

, 2011
Although there is increasing recognition internationally of the significance of social and emotional health and wellbeing for the healthy development of young people, the levels of support that governments provide for mental health policy and programme ...
Slee, Phillip T., Askell-Williams, Helen, Helen Askell-Williams, Dix, Katherine, Phillip T. Slee, Dix, Katherine Louise, Slee, Phillip T, Katherine Dix   +7 more
core   +1 more source

A therapeutic intervention in a primary school. [PDF]

, 2018
As a consequence of interrogating pupil progress data, the primary school in this study identified apparent inequalities in the rates of progress in Reading and Mathematics made by male and female pupils in Key Stage Two cohorts.
Greenhough, Lynne C.
core   +1 more source