Results 131 to 140 of about 1,534,833 (311)

Role of the Locus Coeruleus in Response to Threat in Anxiety Disorders and Posttraumatic Stress Disorder: An Ultra-High-Field 7T Functional Magnetic Resonance Imaging Study

Biological Psychiatry Global Open Science
Background: By harnessing the enhanced spatial resolution and signal power of high-field 7T magnetic resonance imaging (MRI), we assessed the functional involvement of the locus coeruleus (LC), together with the broader threat circuitry, in anxious ...
Sarah C. Boukezzi, Philipp T. Neukam, Nicholas Balderston, Yael Jacob, Derek A. Smith, Yolanda Whitaker, Sarah B. Rutter, Vicki Soogrim, Adriana Feder, Dennis S. Charney, Christian Grillon, Prantik Kundu, Priti Balchandani, Laurel S. Morris, James W. Murrough   +14 more
doaj   +1 more source

Nature‐Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes

Advanced Science, EarlyView.
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang, Qiyang Ding, Lei Shi, Ji Xia, Shuyue Zhang, Chenxin Jian, Yixiao Yan, Xiuhua Luo, Jiarui Wang, Ming Cheng, Yiqiong Jia, Hao Tian, Wei Gao   +12 more
wiley   +1 more source

Using Drift Diffusion and RL Models to Disentangle Effects of Depression On Decision-Making vs. Learning in the Probabilistic Reward Task

Computational Psychiatry
The Probabilistic Reward Task (PRT) is widely used to investigate the impact of Major Depressive Disorder (MDD) on reinforcement learning (RL), and recent studies have used it to provide insight into decision-making mechanisms affected by MDD.
Daniel G. Dillon, Emily L. Belleau, Julianne Origlio, Madison McKee, Aava Jahan, Ashley Meyer, Min Kang Souther, Devon Brunner, Manuel Kuhn, Yuen Siang Ang, Cristina Cusin, Maurizio Fava, Diego A. Pizzagalli   +12 more
doaj   +1 more source

School Stress and Anxiety Among High School Students

International Journal of Humanities and Applied Social Science
School is often the main source of stress and anxiety for adolescents. While stress can be a normal response to challenges, excessive and prolonged stress may result in fear of failure, feelings of inadequacy, and anxiety, with negative effects on well-being and academic outcomes.
Andreja Kozmus, Janja Kozmus, Jure Kozmus   +2 more
openaire   +1 more source

The relations between cognitive，emotional，and behavioral aspects of junior-high and high school stuclents\u27 attitudes toward learning: A multiple population analysis [PDF]

, 2017
The present study investigates the relations between cognitive，emotional, and behavioral aspects of junior-high and high school students\u27 attitudes toward learning and the differences in those attitudes due to level of schooling.
Ishikuma Toshinori, Kodama Hiromi, Toyama Miki, 兒玉 裕巳, 外山 美樹, 石隈 利紀   +5 more
core  

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Personality and cognitive factors implicated in depression and anxiety in multiple sclerosis: A systematic review and meta-analysis

Journal of Affective Disorders Reports
Background: Depression and anxiety are prevalent among persons living with multiple sclerosis (plwMS) and are linked to negative prognostic outcomes. Cognitive theories posit that personality and cognitive factors confer risk for depression and anxiety ...
Rebekah A. Davenport, Isabel Krug, Nicole Rickerby, Phuong Linh Dang, Elizabeth Forte, Litza Kiropoulos   +5 more
doaj   +1 more source

MEMAHAMI NARASI KOMUNIKASI PENYESUAIAN DIRI ANAK TUNARUNGU DI SEKOLAH INKLUSI [PDF]

, 2018
Deaf aand hard-hearing children that goes to inclusive school often find difficulties in adjusting themselves in inclusive school environment. this several factors are affecting this condition including psychosocial, communication, and behavioral factors
Alysha , Paxia Susilo
core  

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Relationships between school anxiety, trait anxiety, state anxiety and depression in a sample of Spanish adolescents [PDF]

, 2013
Diferentes estudios han analizado la ansiedad escolar como un constructo unitario sin atender a las diferentes situaciones y sistemas de respuesta que conforman este constructo.
García-Fernández, José Manuel, Inglés, Cándido J., Martínez-Monteagudo, Mari Carmen   +2 more
core   +1 more source