Results 91 to 100 of about 8,777,452 (313)

Praxisforschung und Transfer – eine Einführung in den Themenschwerpunkt

WE_OS-Jahrbuch, 2019
Im vorliegenden Beitrag wird aufgezeigt, dass die Hoffnungen auf Transfer der Ergebnisse empirischer Bildungsforschung in die pädagogische Praxis sich nicht in dem Maße erfüllen, wie dies vor einigen Jahren noch erwartet wurde.
Martin Heinrich, Gabriele Klewin
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Walley School Community Arts Center Feasibility Study [PDF]

, 2011
The Walley School community arts center initiative began in the fall of 2011 as a joint project between the Town of Bristol and Roger Williams University’s School of Architecture.
Bob Miklos,Kelly Ard, Scott Slarsky,, Hank Kniskern, John McQuilken, Robert Rambo,, Robinson, Arnold   +2 more
core   +1 more source

Schulentwicklung, Praxisforschung und interner Transfer

WE_OS-Jahrbuch, 2019
Ausgehend von als noch nicht weitreichend genug empfundenen Transferaktivitäten am Oberstufen-Kolleg im Anschluss an Forschungs- und Entwicklungsprojekte (FEP) wird im vorliegenden Beitrag die Frage nach dem Zusammenhang von Forschungs- und ...
Gabriele Klewin, Martin Heinrich
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cyberbullying - when does a school authority\u27s liability in tort end? [PDF]

, 2015
Cyberbullying in schools is increasing on an alarming rate. The development of the Internet and smartphone technology have increased the potential scope of a school authority’s duty of care for its students.
Francis, Tryon, Handal, Boris, Khalil, Jessica, Pelletier, Robert   +3 more
core   +1 more source

"... There's so much going on unspoken in the back of the mind ..." —The Use of Repertory Grid Technique as a Qualitative Heuristic Research Design to Understand Teachers' Perceptions of Parents

Forum: Qualitative Social Research, 2007
Studying subjective attitudes has to answer the question about the possibilities of expressing personal systems of meanings and about the possibilities of reconstructing the verbalized meanings by the researchers.
Elisabeth Rangosch-Schneck
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Already at a disadvantage? ICT in the home and children's preparation for primary school. (ICT Research Bursaries 2004 - Final Report) [PDF]

, 2005
The aim of this study is to investigate the impact of socio-economic disadvantage on pre-school children's development of competences in information and communications technologies (ICT). The study focuses on children's experiences of ICT in the home and
Becta (British Educational Communication and Technology Agency) (Funder), Downey, Susan, McPake, Joanna, Plowman, Lydia, Sime, Daniela, Stephen, Christine   +5 more
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source