Results 41 to 50 of about 3,338,488 (310)
High School Failure, a Systematic Review in the Social Sciences
Introduction. This study aims to examine the issue of high school failure in social sciences through a systematic review. It aims to provide a critical assessment of research on this subject. It seeks to question the very construct of high school failure,
Silvana Hernández-Ortiz +2 more
doaj +1 more source
New York City's Middle-Grade Schools: Platforms for Success or Pathways to Failure? [PDF]
This report, which is part of the New York City Coalition for Educational Justice's (CEJ) campaign to transform the city's middle-grade schools into platforms for success for all our city's students, demonstrates that New York City's middle-grade schools
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Is "Turnaround" a useful model for low-performing schools?
Since passage of the No Child Left Behind act in 2001, all states have been under federal pressure to identify “failing schools.” The US Department of Education has strongly encouraged “turnaround” as an option for schools to use in order to improve ...
Sandra Stotsky, Trae Holzman
doaj
Here, we present a systematic review of the literature on Early Leaving from Education and Training (ELET), which uses the life course paradigm as an explanatory model or approach.
Laura Guerrero-Puerta +1 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Okul Başarısızlığı Nedeniyle DKT Kliniği’ne Başvuran Epileptik Çocukların Değerlendirilmesi
Amaç: Okul başarısızlığı tek bir nedene bağlı olmamakla birlikte, bireyin genel sağlık durumu, doğup büyüdüğü, içinde bulunduğu aile ve psiko-sosyal çevre, akademik beceri azlığı, ekonomik koşullar gibi pek çok faktörden ...
Merve Savaş +4 more
doaj
Risk and resilience:Crime and violence prevention in Aboriginal communities [PDF]
Developmental prevention involves the manipulation of multiple risk and protective factors early in developmental pathways that lead to offending, often at transition points between life phases.
Herd, Bruce +2 more
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source

