Results 51 to 60 of about 1,813,642 (313)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Active Shooter Events: The Guardian Plan
The decision on how to protect the children and youth while at schools is a serious conversation with varying agreements on the best practices. Some feel that school personnel should not be trained nor expected to be able to react to an armed person ...
David R. Walker, Pauline M. Sampson
doaj
Impact Philanthropy to Improve Teaching Quality: Focus on High-Need Secondary Students [PDF]
Offers models for improving teachers' skills, including through apprenticeships and in-school mentoring; for creating an environment for great teaching through better leadership and whole-school reform; and guidance for donors on the policy ...
Katherina Rosqueta +3 more
core
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A vast body of research supports the notion that school leadership is the second most influential factor on student achievement, behind only the classroom teacher (Davis & Darling-Hammond, 2012; Lynch, 2012; Mendels & Mitgang, 2013; Miller, 2013; Pannell,
Summer Pannell, Lisa White
doaj
Securing a College Prep Curriculum for All Students [PDF]
Presents a case study of community organizing for school reform by Los Angeles' Community Coalition: how its intergenerational campaign for college preparatory classes shaped leadership development, district policy, school capacity, and student ...
Kavitha Mediratta +2 more
core
The role of whole-school contexts in shaping the experiences and outcomes associated with professional development [PDF]
Review of the article 'The role of whole-school contexts in shaping the experiences and outcomes associated with professional development'. The study examined the in-service programme in relation to different school contexts (size, type, disadvantaged ...
Harris, Linda
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Accountability and Students' Needs
Our schools are working under many pressures often with increased expectations and less resources. These increased expectations hold administrators and teachers to high accountability standards while working with increased diverse populations of students.
Pauline M. Sampson, Kerry L. Roberts
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

