Results 81 to 90 of about 1,813,642 (313)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
An Examination of Adult Bullying in the K-12 Workplace: Implications for School Leaders
School Leadership Review, 2019 The issue of bullying in K-12 schools usually brings images of students to mind, but a recent quantitative study of a sample from K-12 school personnel in Michigan showed that 27.8% of adults in the K-12 workplace consider themselves the target of an ...
Cynthia J. Kleinheksel +1 more
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Getting Honest About Grad Rates: How States Play the Numbers and Students Lose [PDF]
, 2005 This report sharply criticizes the way states calculate and report graduation statistics. The analysis also rebukes the U.S. Department of Education for failing to exert leadership by demanding that states get honest about graduation rates.
Daria Hall
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
School Leadership Review, 2013 One thing Texans can count on for 140 days every odd year is an interesting legislative session. Not only did the 83rd legislative session deliver on interesting, it continues since as of this writing, the second called special session is “in-session ...
Timothy B. Jones
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
School Leadership Review, 2019 Ten middle school principals of Title I charter schools were interviewed in this qualitative, phenomenological narrative study to explore the influence of parental involvement on students’ success in Title I charter schools in Texas as perceived by ...
Salih Aykac, Clementine Msengi
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Service-Learning – preparing students for leadership [PDF]
, 2007 This paper explores ways in which participating in a service-learning program can enhance student leadership in secondary schools. The research is based on the perceptions of teachers who coordinate service-learning in eleven Catholic secondary schools ...
Lavery, Shane D
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Building Capacity for Quality Leadership with English Language Learners
School Leadership Review, 2009 Waxman, Téllez, and Walberg (2004) advocated that school leaders must assist staff developers in providing English language learner (ELLs)-related professional development that includes “demonstration of theories of language, sustained coaching, and ...
John Leonard +2 more
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