Results 41 to 50 of about 2,872,164 (338)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
PENGELOLAAN PERPUSTAKAAN SEKOLAH SMAN 1 BUKIT SUNDI DAN SMAN 1 LEMBANG JAYA KABUPATEN SOLOK
Dinamisia, 2018 IbM program aims to provide understanding to partners about the concept and implementation of library management in accordance with library management procedures. The targets to be achieved are as follows.
Desriyeni Desriyeni
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Book Damage and Repair in School Libraries
Journal of New LibrarianshipThe author is a trained book conservator and frequently gives free book repair workshops to local public and school librarians. This study was a nationwide survey of American school librarians to inform future workshops.
Heather Parks
doaj +1 more source
Revista Interamericana de Bibliotecología, 2017 This study conducted a review of government initiatives and projects aimed at strengthening school libraries in the country, with special emphasis in the city of Medellin, from the 19th century to the second decade of the 21st century.
Sandra Patricia Bedoya Mazo
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Analisis dan Perancangan Sistem Informasi Perpustakaan Sma Negeri Xyz
ComTech, 2014 Library information system analysis and design for public senior high school XYZ in South Tangerang aims to identify needs of data and information about library operational transaction in the school.
Titan Titan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Knjižnica, 2002 The analysis of the results of a questionnaire answered by Slovene primary and secondary school librarians is presented in the article. The purpose of the study was to determine if library user studies were being performed in our school libraries. It was
Zdenka Verlič
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Páginas a&b, 2020 The research problem consists on the following question: how to structure an information mediation activity to work with fan and fandoms activities in school libraries?
Everton da Silva Camillo +1 more
doaj +1 more source