Results 131 to 140 of about 7,340,394 (307)
Detecting Important Life Events on Twitter Using Frequent Semantic and Syntactic Subgraphs [PDF]
, 2016 Identifying global events from social media has been the focus of much research in recent years. However, the identification of personal life events poses new requirements and challenges that have received relatively little research attention.
Alani, Harith +5 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cogent EducationSeveral factors influence adolescents’ life satisfaction. At school, peer relatedness and school supportiveness, as well as individual self-perceptions such as academic self-efficacy, promote life satisfaction.
Luciana Castelli, Jenny Marcionetti
doaj +1 more source
The tree of life as a methodological metaphor [PDF]
, 2013 The Tree of Life is an ancient motif that appears in many cultures and religions. The Tree is symbolic of the interconnected nature of our world(s) and is often used as a reminder of the sacredness of life and its connection to the earth.
Baynes, Renee
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The Education and Miseducation of Boys in Cultural, Political, and Christian Perspective [PDF]
, 2010 The trend of higher male achievement at of all levels of education has reversed in the last twenty years, in almost every major country except Japan, sparking global political and social debate about this intriguing phenomenon.
Bulgin, Roseclaire +1 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Education and Crime over the Life Cycle [PDF]
This paper provides a framework within which to study the equilibrium impact of alternative policies. We develop an overlapping generation, life-cycle model with endogenous education and crime choices.
Giovanni Gallipoli, Giulio Fella
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Getting Communities Involved in Improving Sexual Health Education [PDF]
, 2002 Since 1994, Public Education Network (PEN) has been working with local education funds (LEFs) to engage communities in developing comprehensive school health programs in public schools.
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