Results 81 to 90 of about 7,340,394 (307)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

HUBUNGAN ANTARA KUALITAS KEHIDUPAN SEKOLAH DENGAN KEDISIPLINAN SISWA KELAS BERPINDAH PADA KELAS XII SMAN 3 SEMARANG

open access: yesJurnal Psikologi Undip, 2013
Purpose of this study was to determine the relationship between quality of school life with student's discipline of moving class at students class XII SMAN 3 Semarang.
Nada Febriani   +2 more
doaj   +1 more source

Martin Luther: A Christian vision of school education [PDF]

open access: yes, 2017
This year marks the five hundredth anniversary of the beginning of the Reformation and there is a renewed interest in the life and work of Martin Luther. This article explores Martin Luther’s vision of school education.
McKinney, Stephen
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Biofilms for babies: introducing microbes and biofilms to preschool-aged children [PDF]

open access: yes, 2017
Microbes are beneficial to life on our planet as they facilitate natural processes such as global nutrient cycling in our environment. This article details a 30-minute activity to introduce pre-school children ranging from 3 to 5 years of age to microbes
Couto, Jillian M.
core   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

GAME AS AN AREA COOPERATIVE PEACE TELESECUNDARIA

open access: yesRa Ximhai, 2016
This work is based on an ongoing investigation of qualitative type that has been developing since 2014 a school Telesecundaria Mexico State through participatory action research, addressing the violence in the classroom through the design ...
Alma Verónica Villa-García
doaj  

From Mansions to Towers: A History of Residence Halls at the University of Wisconsin-Eau Claire [PDF]

open access: yes, 2012
The construction of the University of Wisconsin-Eau Claire's residence halls has generally followed that of the national trend. The school struggled to find enough funds to build residence halls in the early years.
Skeen, Mitchell A.
core   +1 more source

Complete Genome Sequences of Mycobacterium smegmatis Phages NihilNomen and Carlyle, Isolated in Las Vegas, Nevada [PDF]

open access: yes, 2019
We present the complete genomes of the Mycobacterium smegmatis phages Carlyle and NihilNomen, isolated from soil in Las Vegas, Nevada. The phages were isolated and annotated by undergraduate students enrolled in the Phage Discovery course offered by the ...
Bhatti, Khadija   +22 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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