Results 91 to 100 of about 7,297,045 (292)
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
The Psychopathology of Basal Ganglia Calcification
Behavioural Neurology, 1989 Basal ganglia calcification (BGC) was found in 36 of 4122 patients undergoing computed tomography as part of a clinical investigation of their psychiatric illness. The prevalence of BGC increased with age in both men and women.
Michael P. Philpot, Shon W. Lewis
doaj +1 more source
BMC Medical Education, 2020 Recognition of the factors affecting the medical students’ academic success is one of the most important challenges and concerns in medical schools. Hence, this study aimed to investigate the mediating effects of metacognitive learning strategies and ...
A. Hayat +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Neurobiology of Disease, 2001 Cisplatin is used in the treatment of ovarian and testicular cancer. Twenty percent of patients cannot be optimally treated because of sensory neurotoxicity.
Stephanie J. Fischer +3 more
doaj
Keeping Dr. Charles Richard Drew’s legacy alive
Journal of the Medical Library Association, 2019 The Charles R. Drew University of Medicine and Science (CDU) recently celebrated its fiftieth anniversary. The university was established to honor Dr. Charles Richard Drew, a pioneer in blood banking. As a tribute to the legacy of CDU and Dr.
Darlene Parker-Kelly, Charles P. Hobbs
doaj +1 more source
Diagnostics Examples from Third-Generation Light Sources [PDF]
arXiv, 2020 This lesson discusses many examples of how the signals from the beam monitors are used to diagnose the beam in circular, third-generation synchrotron light sources. During the school, diagnostic examples in other machines (e.g. colliders, CTF3, linacs and free-electron lasers (FEL), and medical accelerators) were given in other lectures.
arxiv
BMC Medical Education, 2014 Traditional, complementary and alternative (TCAM) medicine is consumed by a large majority of the South African population. In the context of increasing overall demand for healthcare this paper investigates the extent to which South African medical ...
Ethel Chitindingu, G. George, J. Gow
semanticscholar +1 more source