Results 161 to 170 of about 7,297,045 (292)

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

3D Modelling to Address Pandemic Challenges: A Project-Based Learning Methodology [PDF]

arXiv
The use of 3D modelling in medical education is a revolutionary tool during the learning process. In fact, this type of technology enables a more interactive teaching approach, making information retention more effective and enhancing students' understanding.
arxiv  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

FEBS Open Bio, EarlyView.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques, Edit Ábrahám, Hiromi Muramatsu, Daniel Youssef Bargieri, Norbert Pardi, Zoltán Lipinszki   +5 more
wiley   +1 more source

878 T cell immunotherapies recruit and activate neutrophils to eliminate tumor antigen escape variants

Journal for ImmunoTherapy of Cancer, 2023
David Ng, Katherine S Panageas, Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Olivier De Henau, Yanyun Li, Billel Gasmi, Cailian Liu, Sara Schad, Rebekka Duhen, Andrew D Weinberg, Mathieu Gigoux, David Redmond, David Schroder, Andrew Chow, Daniel Hirschhorn, Lukas kraehenbuehl, Isabell Schulze, Aliya Holland, Jean Albrengues, Mikala Egeblad, Arshi Arora, Xue-Yan He, Linda Hamadene, Travis Hollmann, Jacob M Ricca, Levi Mark B Mangarin, Anne-Laure Flamar, Heyjin Choi, Czrina A Cortez, Allison Betof Warner, Gabrielle A Rizzuto, Christine N Spencer   +33 more
doaj   +1 more source

Monitoria de técnica operatória e cirurgia experimental e sua relevância na formação médica

Revista Brasileira de Educação Médica
INTRODUÇÃO: A monitoria de Técnica Operatória e Cirurgia Experimental (Toce) da Faculdade de Medicina da Bahia (UFBA) é uma atividade extracurricular com a finalidade de aprofundar o aluno nos fundamentos teóricos e práticos da Toce. Em 2009, a monitoria
Gabriel de Souza Albuquerque, Rogério Rafael da Silva Mendes, Bruno da Costa Rocha, Mário de Castro Carreiro   +3 more
doaj   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Book review of “Here, there, everywhere—A memoir” by Peter Almond

, 2022
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022.
Bruce J. Gerbi
wiley   +1 more source

TAp63γ is the primary isoform of TP63 for tumor suppression but not development

Cell Death Discovery
TP63 is expressed as TAp63 and ΔNp63 from the P1 and P2 promoters, respectively. While TAp63 and ΔNp63 are expressed as three TAp63α/β/γ and ΔNp63α/β/γ due to alternative splicing, only p63α (TA and ΔN) and p63γ (TA and ΔN) proteins are found to be ...
Xinbin Chen, Wenqiang Sun, Xiangmudong Kong, Xin Ming, Yanhong Zhang, Wensheng Yan, Shakur Mohibi, Mingyi Chen, Keith Mitchell, Jin Zhang   +9 more
doaj   +1 more source