Results 241 to 250 of about 112,215 (282)

The cardiac pacemakers: A paradigm of robustness in evolutionary biology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley   +1 more source

Semiclassical inequalities for Dirichlet and Neumann Laplacians on convex domains

open access: yesCommunications on Pure and Applied Mathematics, Volume 79, Issue 3, Page 762-822, March 2026.
Abstract We are interested in inequalities that bound the Riesz means of the eigenvalues of the Dirichlet and Neumann Laplacians in terms of their semiclassical counterpart. We show that the classical inequalities of Berezin–Li–Yau and Kröger, valid for Riesz exponents γ≥1$\gamma \ge 1$, extend to certain values γ<1$\gamma <1$, provided the underlying ...
Rupert L. Frank, Simon Larson
wiley   +1 more source

SKALE: An Interpretable Multiscale Machine Learning Model for Decoding Phase‐Specific Protein Aggregation in Neurodegenerative Proteinopathies

open access: yesAggregate, Volume 7, Issue 2, February 2026.
Protein aggregation drives diverse degenerative diseases, yet its molecular origins are difficult to predict. SKALE uses interpretable machine learning to link sequence, structure, and dynamics, revealing how local structural weakening triggers aggregation.
Wei Xuan Wilson Loo   +7 more
wiley   +1 more source

Remark on the stabilization for a Schrödinger equation with double power nonlinearity

open access: green, 2019
Jaime E. Muñoz Rivera   +4 more
openalex   +2 more sources

Vildagliptin and Omarigliptin Differentially Bind to DPP‐4 Homodimers and Modulate Osteoclast‐Mediated Bone Resorption

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
Vildagliptin and omarigliptin, dipeptidyl peptidase‐4 (DPP‐4) inhibitors, have differential effects on bone cells. Although vildagliptin improved the bone microstructure of high‐fat diet‐fed rats, it was unable to downregulate osteoclastogenesis or the expression of key osteoclast transcripts.
Ratchaneevan Aeimlapa   +11 more
wiley   +1 more source

Molecular basis and biological relevance of bacterial and plant pinoresinol/lariciresinol reductase specificities

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract A bacterial pinoresinol/lariciresinol reductase (PLR) homolog named NrPinZ was obtained from a Novosphingobium rhizosphaerae sp. LY bacterial strain, with NrPinZ being part of its 5‐step biochemical system catabolizing pinoresinol into coniferyl aldehyde and vanillin.
Clyde A. Smith   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy