Results 61 to 70 of about 3,015 (151)
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Jakub Janáč +8 more
wiley +1 more source
Seniority‐Zero Quadratic Canonical Transformation Theory
We construct a unitary transformation of electronic Hamiltonians using quadratic canonical transformation theory, choosing the transformation to minimize the non‐seniority‐zero elements of the transformed Hamiltonian. This allows us to add dynamic correlation to the static correlation inherent in orbital‐optimized doubly‐occupied (seniority‐zero ...
Daniel F. Calero‐Osorio, Paul W. Ayers
wiley +1 more source
High‐Energy Topological Edge States and Strain‐Induced Multiple Flat Bands in a Honeycomb Lattice
This work proposes a novel anti‐twig edge in the honeycomb lattice that supports two symmetric high‐energy edge states. Moreover, the suppression or enhancement of the high‐energy edge state is observed, and strain‐induced multiple flat bands are produced.
Xiaoqin Bai +4 more
wiley +1 more source
We report a scalable biocatalytic cascade that converts CO2 and acetaldehyde to pyruvate via a newly characterized pyruvate decarboxylase, followed by stereoselective reduction to lactic acid. The system enables fully switchable enantioselectivity using either L‐ or D‐lactate dehydrogenases.
Silvia Fruncillo +9 more
wiley +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Evolution and Conceptual Insights into the Geometric Phase of Light: A Comprehensive Review
This review presents a unified account of the geometric phase of light, linking its fundamental principles to diverse manifestations in polarization, spatial, and vector modes. By connecting theoretical frameworks with key experimental realizations, it reveals a coherent physical picture that deepens understanding and stimulates new directions in ...
A. Srinivasa Rao
wiley +1 more source
ABSTRACT Aquaculture has overtaken capture fisheries as the main source of aquatic animal protein, marking a critical step in global food security. Yet, rapid intensification faces major challenges, including disease outbreaks, environmental degradation, and dependence on wild‐caught fish for feed.
Suvadip Ghara +8 more
wiley +1 more source
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source
On the Meaning of Localization in Non‐Local Quantum Field Theory
In non‐local quantum field theory nature does not necessarily allow objects or events to be localized to exact mathematical points. Instead any physical measurement has a built‐in finite resolution set by the non‐locality scale. Spacetime remains continuous and Lorentz‐covariant, but below this scale pointlike localization becomes an idealization ...
E. J. Thompson
wiley +1 more source
Enhanced Electron Reflection at Mott‐Insulator Interfaces
A condensed‐matter analog of the Klein paradox is demonstrated at a Mott‐insulator‐semiconductor interface. Using the hierarchy of correlations, Schrödinger‐like equations for doublons and holons as well as boundary conditions are derived. For incident energies below mid‐gap, the interface exhibits anomalous reflection probabilities exceeding unity ...
Jan Verlage, Peter Kratzer
wiley +1 more source

