Results 251 to 260 of about 102,370 (356)

Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen   +13 more
wiley   +1 more source

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme   +12 more
wiley   +1 more source

Impairment of PMP22 transgenic Schwann cells differentiation in culture: implications for Charcot-Marie-Tooth type 1A disease

open access: green, 2004
Lucilla Nobbio   +9 more
openalex   +2 more sources

Cervical Intranodal Schwannoma and Its Malignant Transformation: A Case Report With Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case report highlights a rare malignant transformation of a cervical intranodal schwannoma in a 46‐year‐old man. The patient first came in with a slow‐growing, painless nodule in the right neck. Surgical excision was performed and histopathological examinations revealed a benign intranodal cellular schwannoma.
Shahab Hussain   +5 more
wiley   +1 more source

A dose escalation and safety study of AAVrh10-mediated Schwann cell-targeted gene therapy for CMT1X. [PDF]

open access: yesNeurotherapeutics
Christou M   +7 more
europepmc   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei   +11 more
wiley   +1 more source

Decoding innate lymphoid cell heterogeneity and plasticity in colorectal cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
This schematic outlines the origin, heterogeneity, and plasticity of ILCs in colorectal cancer. Created in BioRender. Yiyi, X. (2026) https://BioRender.com/0kwrvq7. Abstract Background In colorectal cancer (CRC), innate lymphoid cells (ILCs) play a vital role in preserving and modulating immune homeostasis within the intestinal environment.
Shuomin Zhang   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy