Results 271 to 280 of about 49,600 (309)

Cytokine and chemokine interactions with Schwann cells: the neuroimmunology of Schwann cells

2007
INTRODUCTION Cytokines, first described as products of the cells of the inflammatory/immune system, are increasingly recognised as acting on non-inflammatory cells as well as being produced by non-inflammatory cells. Nowhere is this more apparent than with cells of the peripheral (PNS) and central (CNS) nervous systems.
Robert P. Lisak, Joyce A. Benjamins
openaire   +2 more sources

Schwann cells transplanted into the CNS

International Journal of Developmental Neuroscience, 1993
AbstractA small volume of purified Schwann cells, cultured from early postnatal rat sciatic nerve, was injected into the hippocampus or fimbria of syngeneic adult hosts. The procedure caused minimal structural disturbance at the transplantation site, with close graft‐host contact and maximal opportunity for integration.The donor Schwann cells were ...
J.M. Lawrence, Geoffrey Raisman, Gary A. Brook   +2 more
openaire   +3 more sources

Developmental Regulation of Schwann Cell Precursors and Schwann Cell Generation

1997
Most myelin-forming and non-myelin-forming Schwann cells of peripheral nerves develop from the neural crest (Anderson, 1993; Bronner-Fraser, 1993; Jessen and Mirsky, 1992; Le Douarin et al., 1991; Marusich and Weston, 1991). The other main glial types in the peripheral nervous system (PNS), are also thought to be derived from the crest.
Rhona Mirsky, A. Brennan, Kristjan R. Jessen, Z. Dong   +3 more
openaire   +2 more sources

Schwann Cell Dysfunction in Acromegaly

The Journal of Clinical Endocrinology & Metabolism, 1970
ABSTRACT The pathologic features observed in a sural nerve biopsy from a subject with acromegalic peripheral neuropathy are presented. Examination of individually teased nerve fibers revealed diffuse segmental demyelination. Since each internodal segment represents the territory occupied by a single Schwann cell, the presence of the segmental loss of ...
openaire   +3 more sources

Epigenetic Control of Schwann Cells

The Neuroscientist, 2018
The journey of Schwann cells from their origin in the neural crest to their ensheathment and myelination of peripheral nerves is a remarkable one. Their apparent static function in enabling saltatory conduction of mature nerve is not only vital for long-term health of peripheral nerve but also belies an innate capacity of terminally differentiated ...
Ki H. Ma, John Svaren
openaire   +3 more sources

Schwann cell growth factors

Cell, 1978
Purified rat Schwann cells were found to proliferate very slowly in normal growth medium containing 10% fetal calf serum (FCS). Crude extracts of bovine pituitary or brain markedly enhanced Schwann cell growth, while similar extracts of nerve roots, liver and kidney did not.
Martin Raff, Jeremy P. Brockes, Ann Hornby-Smith, Erika R. Abney   +3 more
openaire   +3 more sources

Schwann cell precursors and their development

Glia, 1991
AbstractDuring development of peripheral nerves, an apparently homogeneous pool of embryonic Schwann cells gives rise to two morphologically and antigenically distinct mature Schwann cell types. These are the myelin‐forming cells associated with axons of larger diameter and the non‐myelin‐forming cells associated with axons of smaller diameter.The ...
Kristjan R. Jessen, Rhona Mirsky
openaire   +2 more sources

Astrocytoma and Schwann cells in coculture

Molecular and Chemical Neuropathology, 1996
Glial fibrillary acidic protein (GFAP) is the principal intermediate filament protein found in mature astrocytes. Although the exact function of GFAP is poorly understood, it is presumed to stabilize the astrocyte's cytoskeleton and help in maintaining cell shape. Previous studies from our laboratory have shown that when astrocytes were cocultured with
Lawrence F. Eng, Lawrence F. Eng, Preeti G. Lal, Roopa S. Ghirnikar   +3 more
openaire   +3 more sources

The Early Life of a Schwann Cell

Biological Chemistry, 2002
Schwann cells are the major glial population of the vertebrate peripheral nervous system. In the adult, they build a protecting sheath around neuronal processes and myelinate large-caliber axons. Already early in development, Schwann cells and neurons establish close contacts.
Christian S. Lobsiger, Ueli Suter, Verdon Taylor   +2 more
openaire   +3 more sources

Imaging of Schwann Cells In Vivo

2011
The ability to examine cells tagged with fluorescent proteins in vivo has led to exciting advances in molecular neurobiology. The integral role of Schwann cells in nerve regeneration is well characterized, but not until recently has dynamic imaging of these critical cells been possible.
Rahul Kasukurthi, Terence M. Myckatyn
openaire   +3 more sources