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Cold Spring Harbor Protocols, 2014
This article introduces methods for the acute purification and primary culture of Schwann cells from the mouse sciatic nerve. Immunopanning can be used to isolate Schwann cells from intact nerves during early postnatal development as well as to purify Schwann cells from adult nerves following sciatic nerve injury.
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This article introduces methods for the acute purification and primary culture of Schwann cells from the mouse sciatic nerve. Immunopanning can be used to isolate Schwann cells from intact nerves during early postnatal development as well as to purify Schwann cells from adult nerves following sciatic nerve injury.
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2021
Abstract Theodor Schwann, a German physiologist and one of the founding fathers of cellular theory, was the first to hypothesize the association between myelin (the insulating fatty substance surrounding peripheral nerve axons) and the cells that later took his name.
Paul J. Kingham, Mikael Wiberg
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Abstract Theodor Schwann, a German physiologist and one of the founding fathers of cellular theory, was the first to hypothesize the association between myelin (the insulating fatty substance surrounding peripheral nerve axons) and the cells that later took his name.
Paul J. Kingham, Mikael Wiberg
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Schwann Cells Promote Cancer Cell Invasion
Cancer Discovery, 2016Abstract Schwann cell contact induces cancer cell dispersion and perineural invasion.
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1982
Although Schwann cells were not a topic in the previous series of this Handbook, their properties were covered in a general review of the peripheral nerve by Porcellati.1 In addition, aspects of protein and lipid metabolism in peripheral nerve undergoing Wallerian degeneration were reviewed.2,3 Interest in the peripheral nervous system has grown over ...
Robert M. Gould +2 more
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Although Schwann cells were not a topic in the previous series of this Handbook, their properties were covered in a general review of the peripheral nerve by Porcellati.1 In addition, aspects of protein and lipid metabolism in peripheral nerve undergoing Wallerian degeneration were reviewed.2,3 Interest in the peripheral nervous system has grown over ...
Robert M. Gould +2 more
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Intermediate Filaments of Schwann Cells
Journal of Neurochemistry, 1982Abstract: Intermediate filaments were prepared from distal stumps of rabbit sciatic nerve 5 weeks after nerve section, at which time Schwann cells account for 85–90% of the cell area. A polypeptide of molecular weight 58,000 was the main component of this fraction. An antiserum raised in guinea pig against this polypeptide stained all cells present in
L, Autilio-Gambetti +3 more
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Schwann Cell Dysfunction in Acromegaly
The Journal of Clinical Endocrinology & Metabolism, 1970ABSTRACT The pathologic features observed in a sural nerve biopsy from a subject with acromegalic peripheral neuropathy are presented. Examination of individually teased nerve fibers revealed diffuse segmental demyelination. Since each internodal segment represents the territory occupied by a single Schwann cell, the presence of the segmental loss of ...
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Astrocyte–Schwann-Cell Coculture Systems
2011Schwann cells are one of the cellular candidates used in repair strategies following trauma and demyelination of the spinal cord. One of the major obstacles in the use of Schwann cells is their limited migratory ability within the astrocytic environment of the CNS and boundary formation between the Schwann cells of the graft and the host astrocytes ...
Fardad T, Afshari, James W, Fawcett
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1996
Abstract Schwann cells support neuronal function in the intact nerve by supplying the myelin sheath around larger axons. Schwann cells are likely to also regulate the ionic environment of axons, provide neurotrophic support, and regulate the periaxonal space.
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Abstract Schwann cells support neuronal function in the intact nerve by supplying the myelin sheath around larger axons. Schwann cells are likely to also regulate the ionic environment of axons, provide neurotrophic support, and regulate the periaxonal space.
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Developmental Regulation of Schwann Cell Precursors and Schwann Cell Generation
1997Most myelin-forming and non-myelin-forming Schwann cells of peripheral nerves develop from the neural crest (Anderson, 1993; Bronner-Fraser, 1993; Jessen and Mirsky, 1992; Le Douarin et al., 1991; Marusich and Weston, 1991). The other main glial types in the peripheral nervous system (PNS), are also thought to be derived from the crest.
K. R. Jessen +3 more
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2000
Abstract Medical eponyms often reflect a single outstanding discovery or a major contribution by the honored person to a particular field of the healing arts. The case of Theodor Schwann, however, represents a somewhat different situation.
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Abstract Medical eponyms often reflect a single outstanding discovery or a major contribution by the honored person to a particular field of the healing arts. The case of Theodor Schwann, however, represents a somewhat different situation.
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