Results 91 to 100 of about 51,731 (281)
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, EarlyView.Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis +2 more
wiley +1 more source
Schwann Cell and Axon Electrical Potential Differences [PDF]
, 1963 Raimundo Villegas +3 more
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Glia, EarlyView.Hemizygous P0T124M mice develop a late‐onset axonopathy at 18 months of age. Pharmacological macrophage targeting with PLX5622 prevents distal axon degeneration in P0T124M mutant mice and mitigates motor impairment. ABSTRACT In several previous studies, we have shown that macrophage targeting with the CSF‐1 receptor specific kinase (c‐FMS) inhibitor ...
Dennis Klein +8 more
wiley +1 more source
Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis
Glia, EarlyView.OECs are similar to satellite glial cells. OECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. OECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs) envelope ...
Katja Senf +3 more
wiley +1 more source
Transcriptional Regulation Induced by cAMP Elevation in Mouse Schwann Cells
ASN Neuro, 2014 In peripheral nerves, Schwann cell development is regulated by a variety of signals. Some of the aspects of Schwann cell differentiation can be reproduced in vitro in response to forskolin, an adenylyl cyclase activator elevating intracellular cAMP ...
Daniela Schmid +2 more
doaj +1 more source
Schwann Cell Precursors; Multipotent Glial Cells in Embryonic Nerves
Frontiers in Molecular Neuroscience, 2019 The cells of the neural crest, often referred to as neural crest stem cells, give rise to a number of sub-lineages, one of which is Schwann cells, the glial cells of peripheral nerves.
Kristjan R. Jessen, Rhona Mirsky
doaj +1 more source
Nature of the Schwann Cell Electrical Potential [PDF]
, 1968 Jorge Villegas +2 more
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Investigating the role of SARM1 in central nervous system
Ibrain, EarlyView.Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang +4 more
wiley +1 more source
Fibronectin and procollagen produced by a clonal line of Schwann cells [PDF]
, 1979 Markku Kurkinen, Kari Alitalo
openalex +1 more source
Interdisciplinary Materials, EarlyView.The PCL‐PLLA‐MgSiO3 composite patch fabricated via electrospinning demonstrates superior therapeutic effects on diabetic wound healing compared to commercially available products, especially neurovascular network recovery. This will provide a promising bioactive patch for future clinical diabetic wound management.
Shunxiang Xu +10 more
wiley +1 more source