Chemical Conversion of Human Fibroblasts into Functional Schwann Cells
Stem Cell Reports, 2014 Direct transdifferentiation of somatic cells is a promising approach to obtain patient-specific cells for numerous applications. However, conversion across germ-layer borders often requires ectopic gene expression with unpredictable side effects.
Eva C. Thoma +13 more
doaj +1 more source
Polyvinylidene Fluoride: Reaction Engineering and Applications
Macromolecular Reaction Engineering, EarlyView.An updated review on polyvinylidene fluoride (PVDF) is presented in this work. Its properties, important areas of application and different methods of production are described, with particular focus on emulsion polymerization, covering the latest advances in formulations and modeling studies.
Burak Hanamirian +2 more
wiley +1 more source
GDF 15 deficiency induces a progressive Schwann cell loss in vivo and regulates their survival and migration in vitro [PDF]
, 2014 Sabrina Walter
openalex +1 more source
In Vitro Reconstruction of Axonal Heat Sensing with a Photothermal Nerve‐on‐a‐Chip
Small, EarlyView.A photothermal nerve‐on‐a‐chip platform is presented that enables precise, localized heating of sensory axons with simultaneous electrical recording. The system reveals millisecond‐scale dynamics of heat‐evoked neural activity and provides a new approach to study how temperature‐dependent ion channel behavior is translated into axonal firing.
Koji Sakai +6 more
wiley +1 more source
Fibrin Inhibits Peripheral Nerve Remyelination by Regulating Schwann Cell Differentiation [PDF]
, 2002 Katerina Akassoglou +3 more
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Aligned cellular and acellular collagen guidance substrates for peripheral nerve repair [PDF]
, 2011 There is a clinical demand to shorten the delay of reinnervation and improve functional recovery after peripheral nerve injury. A peripheral nerve repair device with the ability to direct and promote axon growth across a lesion would be a promising ...
Georgiou, Melanie +3 more
core
VIEW, EarlyView.Schematic representation of the microfluidic platform with its advantages. Abstract A major challenge in pharmacology is the limited selectivity of therapeutic compounds toward specific tissues or cells. Drugs often distribute systemically before reaching the intended site of action, affecting nontarget cells and potentially reducing efficacy or ...
Maria Testa +8 more
wiley +1 more source
C-type natriuretic peptide is a Schwann cell-derived factor for development and function of sensory neurons [PDF]
, 2009 Ichiro Kishimoto +4 more
openalex +1 more source
Audiological Characteristics in Vestibular Schwannoma Patients
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng +4 more
wiley +1 more source
Transcriptional Regulation Induced by cAMP Elevation in Mouse Schwann Cells
ASN Neuro, 2014 In peripheral nerves, Schwann cell development is regulated by a variety of signals. Some of the aspects of Schwann cell differentiation can be reproduced in vitro in response to forskolin, an adenylyl cyclase activator elevating intracellular cAMP ...
Daniela Schmid +2 more
doaj +1 more source