Results 111 to 120 of about 68,795 (281)

Matrix metalloproteinase 7 promoted Schwann cell migration and myelination after rat sciatic nerve injury

Molecular Brain, 2019
Schwann cells experience de-differentiation, proliferation, migration, re-differentiation and myelination, and participate in the repair and regeneration of injured peripheral nerves.
Hongkui Wang, Ping Zhang, Jun Yu, Fuchao Zhang, Wenzhao Dai, Sheng Yi   +5 more
doaj   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Chemical Conversion of Human Fibroblasts into Functional Schwann Cells

Stem Cell Reports, 2014
Direct transdifferentiation of somatic cells is a promising approach to obtain patient-specific cells for numerous applications. However, conversion across germ-layer borders often requires ectopic gene expression with unpredictable side effects.
Eva C. Thoma, Claudia Merkl, Tobias Heckel, Rachel Haab, Frederic Knoflach, Corinne Nowaczyk, Nicholas Flint, Ravi Jagasia, Sannah Jensen Zoffmann, Hoa Hue Truong, Pascal Petitjean, Sebastian Jessberger, Martin Graf, Roberto Iacone   +13 more
doaj   +1 more source

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog

, 2006
We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Umehara, F, Meier, C, Turmaine, M, Jessen, KR, Sharghi-Namini, S, Sahni, V, Mirsky, R   +6 more
core  

FGF/heparin differentially regulates Schwann cell and olfactory ensheathing cell interactions with astrocytes: a role in astrocytosis [PDF]

, 2007
After injury, the CNS undergoes an astrocyte stress response characterized by reactive astrocytosis/proliferation, boundary formation, and increased glial fibrillary acidic protein (GFAP) and chondroitin sulfate proteoglycan (CSPG) expression. Previously,
Fairless, R., Barnett, Susan C, Smith, George M, Montague, Paul, Fairless, Richard, Frame, M.C., Toft, A., Barnett, S.C., Santos-Silva, A., Riddell, J.S., Toft, Andrew, Riddell, John S, Montague, P., Smith, G.M., Frame, Margaret C, Santos-Silva, Alessandra   +15 more
core   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
Idiopathic subglottic stenosis (iSGS) is a challenging variant of airway stenosis associated with consistent distal airway abnormalities on bronchoscopy, including pits, depressions, and striations. Despite these findings, most patients demonstrate normal or mild–moderate obstruction on spirometry.
Sydney Ring, Andrew Jay Bowen, Tessa Griffin, J. Scott Ferguson, Seth H. Dailey   +4 more
wiley   +1 more source

Morphology of Schwann cells.

, 2016
Spindle-elongated morphology of Schwann cells under phase-contrast microscopy (A). An immunocytochemical assessment of Schwann cells shows positivity for the S100 protein (B). Scale bar, 100 (A) and 50 μm (B).
Shiqing Feng (3595211), Yunqiang Xu (847339), Zhenhui Zhang (847340), Ruixin Li (169225), Dong Li (212687), Xuyi Chen (847341)   +5 more
core   +1 more source

Polyvinylidene Fluoride: Reaction Engineering and Applications

Macromolecular Reaction Engineering, EarlyView.
An updated review on polyvinylidene fluoride (PVDF) is presented in this work. Its properties, important areas of application and different methods of production are described, with particular focus on emulsion polymerization, covering the latest advances in formulations and modeling studies.
Burak Hanamirian, Giuseppe Storti, Mattia Sponchioni   +2 more
wiley   +1 more source