Results 61 to 70 of about 51,731 (281)

Thermal Annealing Enhances Piezoelectricity and Regenerative Potential of PVDF‐TrFE Nanofiber Scaffolds

Advanced Materials Technologies, EarlyView.
Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko, Holly M. Poling, Maulee Sheth, Supasek Kongsomros, Andrew E. Bryan, Manju Sharma, Akaljot Singh, Hasan A. Reza, Kathryn A. Wikenheiser‐Brokamp, Takanori Takebe, Michael A. Helmrath, Greg M. Harris, Leyla Esfandiari   +12 more
wiley   +1 more source

Bioengineered Models of Nerve Regeneration

Advanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson, John Paul Frampton   +1 more
wiley   +1 more source

Tissue Engineered Bands of Büngner for Accelerated Motor and Sensory Axonal Outgrowth

Frontiers in Bioengineering and Biotechnology, 2020
Following peripheral nerve injury comprising a segmental defect, the extent of axon regeneration decreases precipitously with increasing gap length. Schwann cells play a key role in driving axon re-growth by forming aligned tubular guidance structures ...
Kate V. Panzer, Kate V. Panzer, Kate V. Panzer, Justin C. Burrell, Justin C. Burrell, Justin C. Burrell, Kaila V. T. Helm, Kaila V. T. Helm, Erin M. Purvis, Erin M. Purvis, Erin M. Purvis, Qunzhou Zhang, Qunzhou Zhang, Anh D. Le, Anh D. Le, John C. O’Donnell, John C. O’Donnell, D. Kacy Cullen, D. Kacy Cullen, D. Kacy Cullen   +19 more
doaj   +1 more source

When Cellulose Moves: Smart Sensors and Actuators

Advanced Materials Technologies, EarlyView.
This review highlights cellulose‐derived soft actuators alongside with cellulose‐based sensors. Emphasis is placed on their integration into multifunctional devices that couple sensing and actuation to mimic natural motion and adaptability. We also discuss the challenges of achieving robust, reversible, and multi‐stimuli‐responsive motion, and outline ...
Francisco Sousa, José F. Malta, Ana P. C. Almeida   +2 more
wiley   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

GABA-B receptors in the PNS have a role in Schwann Cells differentiation?

Frontiers in Cellular Neuroscience, 2013
GABA-B receptor mediates the inhibitory transmission of -aminobutyric acid in the mammalian nervous system, being present in neurons and also in glial cells.
Patrizia eProcacci, Marinella eBallabio, Luca Franco Castelnovo, Cristina Maria Mantovani, Valerio eMagnaghi   +4 more
doaj   +1 more source

Intrinsic migratory properties of cultured Schwann cells based on single-cell migration assay. [PDF]

PLoS ONE, 2012
The migration of Schwann cells is critical for development of peripheral nervous system and is essential for regeneration and remyelination after nerve injury.
Ying Wang, Hong-Lin Teng, Zhi-hui Huang
doaj   +1 more source

Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration

Advanced Science, EarlyView.
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan, Wei Yu, Xinggui Wen, Xiangdong Ding, Xiang Li   +4 more
wiley   +1 more source

Expression of ATF3 and axonal outgrowth are impaired after delayed nerve repair

BMC Neuroscience, 2008
Background A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known.
Dahlin Lars B, Saito Harukazu
doaj   +1 more source

Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy

Advanced Science, EarlyView.
As an inevitable disease, muscle atrophy has received more attention. Because the factors that induce this disease are diverse, achieving a complete cure is still impossible. Wearable bioelectronics provides a more comfortable, low‐cost, and efficient way of home care for the monitoring and treatment of muscle atrophy. Therefore, this review summarizes
Shuai Zhang, Renjie Tan, Shuo Meng, Ke Zhang, Jinlian Hu   +4 more
wiley   +1 more source