Results 91 to 100 of about 280,960 (341)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Modellierung von Bodentypen und Bodeneigenschaften im Oberengadin (Schweiz) mit Hilfe eines Geographischen Informationssystems (GIS) [PDF]

open access: yesGeographica Helvetica
Detaillierte Bodenkarten im schweizerischen Alpenraum existieren praktisch nicht. Die einzige Grundlage ist die Bodeneignungskarte im Massstab 1:200'000. Mit der GIS-Datenbasis des Kantons Graubünden wurde versucht, über eine räumliche Analyse einen Teil
M. Egli   +5 more
doaj   +1 more source

Verwendungsraten von Prothesen der unteren Extremität in Deutschland und der Schweiz: Ein Vergleich der Jahre 2005-2008 [PDF]

open access: yes, 2018
Zusammenfassung: Hintergrund: In den USA hat die Verwendung der totalen Hüftprothese innerhalb der letzten Dekade stark zugenommen. Es ist jedoch nicht bekannt, ob sich dieser Trend auf andere Länder übertragen lässt.
Dudda, M.   +5 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Presenteeism and team culture: a qualitative study of health care and office professionals / Präsentismus und Teamkultur: eine qualitative Befragung von Gesundheit- und Bürofachpersonen

open access: yesInternational Journal of Health Professions
Presenteeism – working even though you are ill – is a widespread phenomenon that has negative consequences for both employees and employers. It particularly affects healthcare professionals (HCPs) and, due to working from home, increasingly also office ...
Klopfenstein Flurina Anna   +4 more
doaj   +1 more source

Perinatal mental disorders in Switzerland : prevalence estimates and use of mental-health services [PDF]

open access: yes, 2017
Background: Perinatal mental disorders (PMDs) are the most common complication of pregnancy and the first postpartum year. Since PMD prevalence and use of mental-health services by perinatal women in Switzerland are unknown, we analysed existing health ...
Bachmann, Nicole   +6 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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