Results 1 to 10 of about 807,151 (385)

Enhancement of sciatic nerve regeneration with dual delivery of vascular endothelial growth factor and nerve growth factor genes

Journal of Nanobiotechnology, 2020
Background Peripheral nerve injury is one common clinical disease worldwide, in which sciatic nerve is anatomically the most challenging to regenerate given its length and large cross-sectional area.
Zhiwei Fang, Xuemei Ge, Xuan Chen, Yang Xu, Wei-En Yuan, Yuanming Ouyang   +5 more
doaj   +2 more sources

Selection of sciatic nerve injury models: implications for pathogenesis and treatment [PDF]

Frontiers in Neurology
Sciatic nerve injury is one of the most frequent peripheral nerve injuries in the world. The loss of motor and sensory function, along with chronic pain caused by sciatic nerve injury, significantly impacts patients’ quality of life.
Pinxi Zhou, Ruhan Zhang, Liangmei Xian, Le Ning, Penghui Lu, Qianyan Liu, Mi Liu   +6 more
doaj   +2 more sources

Sciatic nerve injury following analgesic drug injection in rats: A histopathological examination

İstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]Sciatic nerve neuropathy can be observed following intramuscular gluteal injections. The histopathological examination of sciatic nerve damage following intramuscular injection in the gluteal region for acute pain treatment is not feasible
Habib Bostan, Murat Çabalar, Serdar Altınay, Yıldıray Kalkan, Levent Tumkaya, Ayhan Kanat, Sabri Balık, Adem Erkut, Dudu Altuner, Ziya Salihoğlu, Abdulkadir Koçer   +10 more
doaj   +2 more sources

Electrophysiological Evaluation of a Sciatic Nerve Degree III Injury Model in Rats [PDF]

Bio-Protocol
Sciatic nerve injury is a prevalent traumatic condition that significantly impacts a patient's quality of life. The sciatic nerve compression injury model is among the most commonly utilized models for investigating nerve repair and regeneration ...
Linyu Chen, Ziyi Wang, Chengyao Wang, Ning Ma, Weiqin Zhao, Shuang Liu, Jiajun Lu, Boyuan Zhao, Hong Sun, Pengcheng Che, Na Dou   +10 more
doaj   +2 more sources

Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)

eLife, 2021
Peripheral nerves are organ-like structures containing diverse cell types to optimize function. This interactive assembly includes mostly axon-associated Schwann cells, but also endothelial cells of supporting blood vessels, immune system-associated ...
Daniel Gerber, J. Pereira, Joanne Gerber, G. Tan, S. Dimitrieva, E. Yángüez, U. Suter   +6 more
semanticscholar   +1 more source

Sciatic Nerve Varices [PDF]

European Journal of Vascular and Endovascular Surgery, 2005
To describe patients presenting with sciatic nerve varices (SNV), presenting pitfalls in diagnosis and management.Case series.Patients were investigated using duplex ultrasonography pre-operatively in three cases. Treatment was undertaken both by surgery and by foam sclerotherapy.Clinically, SNV appeared just below the popliteal skin crease, lateral to
STEFANO RICCI, MIHAEL GEORGIEV, ARKADIUSZ JAVIEN, ZAMBONI, Paolo   +3 more
openaire   +4 more sources

High Division of Sciatic Nerve: A Cadaveric Study [PDF]

International Journal of Anatomy Radiology and Surgery, 2016
Introduction: Several authors give significant numbers of reports regarding anatomical variation of high division of sciatic nerve. This variation (high division of sciatic nerve) may result in sciatica, nerve injury during deep intramuscular ...
Shivaji B Sukre, Asim Mohsin Badaam
doaj   +1 more source

The level of the sciatic nerve division and its relations to the piriform muscle [PDF]

Vojnosanitetski Pregled, 2005
Background. The sciatic nerve, as the terminal branch of the sacral plexus, leaves the pelvis through the greater sciatic foramen beneath the piriform muscle.
Ugrenović Slađana Z., Jovanović Ivan D., Krstić Vladislav, Stojanović Vesna R., Vasović Ljiljana P., Antić Svetlana, Pavlović Snežana S.   +6 more
doaj   +1 more source

Dexmedetomidine Improves Locomotor Function and Alleviates Thermal Hyperalgesia Following Sciatic Nerve Crush Injury in Rats [PDF]

International Neurourology Journal, 2020
Purpose The effects of dexmedetomidine on locomotor function and thermal hyperalgesia in sciatic nerve crush injury (SNCI) were investigated using rats.
Myung-Soo Jang, Jin Hee Han, Dong-Ok Kim, Gil Woo, Jae-Ik Kwon, Jun-Young Chung, Bong-Jae Lee, Jae-Woo Yi   +7 more
doaj   +1 more source

Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor and vascular endothelial growth factor repair long-distance sciatic nerve defects in rats

Theranostics, 2020
Autologous nerve transplantation, which is the gold standard for clinical treatment of peripheral nerve injury, still has many limitations. In this study, aligned chitosan fiber hydrogel (ACG) grafted with a bioactive peptide mixture consisting of RGI ...
F. Rao, Yanhua Wang, Dianying Zhang, Chang‐feng Lu, Z. Cao, Jiajie Sui, Mengjiao Wu, Yawen Zhang, W. Pi, Bo Wang, Y. Kou, Xiumei Wang, Peixun Zhang, B. Jiang   +13 more
semanticscholar   +1 more source