Results 151 to 160 of about 65,822 (289)

Anatomical Study of Lateral Compression II Screw Path and Entry Parameters Based on Three‐Dimensional CT Image Reconstruction Techniques

open access: yesOrthopaedic Surgery, Volume 17, Issue 5, Page 1454-1463, May 2025.
This graphical abstract illustrates a study where 43 adult patients (21 males, 22 females) underwent CT scans to reconstruct 3D pelvic models using Mimics and 3‐Matic software. The analysis measured the Lateral Compression II (LC‐II) screw path, revealing sex‐based anatomical differences that could improve the precision and safety of percutaneous LC‐II
Xingye Du, Yong Liu, Xuefeng Jiang
wiley   +1 more source

Locked plate versus modified clamp‐rod internal fixation for feline corpus ilium fractures: A comparative clinical study

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To evaluate the applicability and clinical effectiveness of a modified clamp‐rod internal fixation (M‐CRIF) system compared with conventional locking plate osteosynthesis in the treatment of feline corpus ilium fractures. Study design Prospective, controlled clinical study.
Nahit Saylak   +4 more
wiley   +1 more source

Skeletal muscle‐specific myostatin overexpression promotes muscle oxidative capacity and fatigue resistance in transgenic mice

open access: yesExperimental Physiology, EarlyView.
Abstract In addition to controlling muscle mass, myostatin may support oxidative metabolism and endurance. Loss of function through gene knockout or post‐natal blockade generally lowers muscle oxidative capacity and increases fatigability. These observations imply that myostatin activation could promote a more oxidative and less fatigable muscle ...
Andy V. Khamoui   +6 more
wiley   +1 more source

Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang   +2 more
wiley   +1 more source

Regimen‐dependent glucocorticoid effects improve muscle performance without altering CNS physiology in mdx mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Defining glucocorticoid efficacy in Duchenne muscular dystrophy requires assessment across muscle, central nervous system (CNS), cardiovascular and systemic domains. Here, juvenile mdx mice were treated over 6 weeks, comparing daily and weekly dosing of prednisolone and vamorolone.
Gretel S. Major   +4 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Oromucosal Administration of a Cannabidiol‐Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain

open access: yesEuropean Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Chronic neuropathic pain (CNP) involves complex interactions between resident and peripheral immune cells, as well as modulation of the endocannabinoid system. Cannabis‐based products have emerged as promising therapeutic options, but their effects on immune cells remain unclear.
Raquel Maria Pereira Campos   +5 more
wiley   +1 more source

Unusual Sciatic Nerve Entrapment by the Inferior Gluteal Artery. [PDF]

open access: yesDiagnostics (Basel)
Wu WT, Hsu YC, Chang KV, Özçakar L.
europepmc   +1 more source

High‐Carbohydrate Diet Enhances Peripheral Nerve Regeneration via Hemoglobin Upregulation in Schwann Cells

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
A short‐term high‐carbohydrate diet enhances peripheral nerve regeneration more effectively than high‐protein or high‐fat diets by upregulating hemoglobin genes in Schwann cells. Increased hemoglobin promotes Schwann cell proliferation and migration, facilitating nerve repair.
Shiying Li   +16 more
wiley   +1 more source

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