By mimicking the ion‐accelerating effect of ion channel receptors in neuron membranes, a biomaterials‐based ionic hydrogel (BIH) is developed, which offers a high ionic conductivity of 7.04 S m−1, outperforming conventional chitosan, cellulose, agarose, starch, and gelatin based ionic hydrogels.
Baojin Chen +7 more
wiley +1 more source
Postoperative pain and morphine consumption after ultrasound-guided femoral and sciatic combined nerve block versus neurostimulation for femoral and sciatic combined nerve block or neurostimulation for femoral nerve block in primary elective total knee arthroplasty. [PDF]
Congreso XXXVII National Meeting of the Spanish Society of Pharmacology with guest society: The British Pharmacological SocietyBackground and Aims: Total knee arthroplasty injuries are extremely painful and merit prompt attention to adequate ...
Bellido-Estevez, Inmaculada +3 more
core
Palmitoylethanolamide is a disease-modifying agent in peripheral neuropathy : pain relief and neuroprotection share a PPAR-alpha-mediated mechanism [PDF]
Peer reviewedPublisher ...
Calignano, A +6 more
core +4 more sources
Sciatic Nerve Palsy following Curved Periacetabular Osteotomy
Curved periacetabular osteotomy (CPO) is used for the treatment of dysplastic hips. Previous studies have reported satisfying outcomes and low rate of severe complications associated with this procedure; however, no case of postoperative sciatic nerve ...
Masahiro Fujita +11 more
doaj +1 more source
A Rabbit Model for Peripheral Nerve Reconstruction Studies Avoiding Automutilation Behavior
Background The rabbit sciatic nerve injury model may represent a valuable alternative for critical gap distance seen in humans but often leads to automutilation. In this study, we modified the complete sciatic nerve injury model for avoiding autophagy.
Jonathan A. Sorkin +6 more
doaj +1 more source
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow +6 more
wiley +1 more source
Cadaveric Study on Variations in the Level of Bifurcation of Sciatic Nerve and its Clinical Implications [PDF]
Introduction: Sciatic nerve is the thickest nerve of the human body arising from the sacral plexus. It bifurcates into tibial nerve and common fibular nerve at any level from the pelvis to the popliteal fossa. Variations in the level of bifurcation of
Mayankkumar D Javia, Sanjay K Vikani
doaj +1 more source
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu +21 more
wiley +1 more source
Epithelioid sarcoma involving sciatic nerve with lung metastasis and local recurrence: A case report
Involvement of a deep peripheral nerve by epithelioid sarcoma (ES) is extremely rare, especially in sciatic nerve. It is a highly aggressive malignant tumor with poor prognosis and comparatively difficult to detect and confirm diagnosis in early stage ...
Maimaiaili Yushan, PhD +4 more
doaj +1 more source
Although autogenous nerve transplantation is the gold standard for treating peripheral nerve defects of considerable length, it still has some shortcomings, such as insufficient donors and secondary injury.
Fa-Dong Liu +7 more
doaj +1 more source

