Results 41 to 50 of about 825,337 (391)

Biodegradable magnesium wire promotes regeneration of compressed sciatic nerves

open access: yesNeural Regeneration Research, 2016
Magnesium (Mg) wire has been shown to be biodegradable and have anti-inflammatory properties. It can induce Schwann cells to secrete nerve growth factor and promote the regeneration of nerve axons after central nervous system injury. We hypothesized that
Bo-han Li, Ke Yang, Xiao Wang
doaj   +1 more source

A Rabbit Model for Peripheral Nerve Reconstruction Studies Avoiding Automutilation Behavior

open access: yesJournal of Brachial Plexus and Peripheral Nerve Injury, 2022
Background The rabbit sciatic nerve injury model may represent a valuable alternative for critical gap distance seen in humans but often leads to automutilation. In this study, we modified the complete sciatic nerve injury model for avoiding autophagy.
Jonathan A. Sorkin   +6 more
doaj   +1 more source

Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome [PDF]

open access: yes, 2017
Rett syndrome (RTT) is a neurological disorder characterized by motor and cognitive impairment, autonomic dysfunction and a loss of purposeful hand skills.
Bahey, Noha G.   +5 more
core   +1 more source

Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section [PDF]

open access: yes, 2003
The central arborizations of large myelinated cutaneous afferents normally extend as far dorsally as the ventral part of lamina II in rat spinal cord. Woolf et al. (1992) reported that after nerve injury some of these afferents sprouted into lamina I and
Hughes, D.I.   +3 more
core   +1 more source

Silencing of circRNA.2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy

open access: yesMolecular Therapy: Nucleic Acids, 2018
Circular RNAs (circRNAs) represent a class of non-coding RNAs that are involved in transcriptional and posttranscriptional gene expression regulation and associated with different kinds of human diseases.
Zhi-bin Zhou   +5 more
doaj   +1 more source

Biomimetic chitosan scaffolds with long-term controlled release of nerve growth factor repairs 20-mm-long sciatic nerve defects in rats

open access: yesNeural Regeneration Research, 2022
Although autogenous nerve transplantation is the gold standard for treating peripheral nerve defects of considerable length, it still has some shortcomings, such as insufficient donors and secondary injury.
Fa-Dong Liu   +7 more
doaj   +1 more source

Chitosan conduit combined with hyaluronic acid prevent sciatic nerve scar in a rat model of peripheral nerve crush injury

open access: yesMolecular Medicine Reports, 2018
In the present study, the effects of hyaluronic acid (HA) combined with chitosan conduit on peripheral nerve scarring and regeneration were investigated in a rat model of peripheral nerve crush injury.
Runxin Li   +11 more
semanticscholar   +1 more source

Measuring neuromuscular junction functionality [PDF]

open access: yes, 2017
Neuromuscular junction (NMJ) functionality plays a pivotal role when studying diseases in which the communication between motor neuron and muscle is impaired, such as aging and amyotrophic lateral sclerosis (ALS).
Del Prete, Zaccaria   +4 more
core   +1 more source

Immune cell distribution and immunoglobulin levels change following sciatic nerve injury in a rat model [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2016
Objective(s): To investigate the systemic and local immune status of two surgical rat models of sciatic nerve injury, a crushed sciatic nerve, and a sciatic nerve transection Materials and Methods:Twenty-four adult male Sprague-Dawley rats were randomly ...
Wei Yuan, Xinhong Feng
doaj  

The potential role of sciatic nerve stiffness in the limitation of maximal ankle range of motion

open access: yesScientific Reports, 2018
It is a long held belief that maximal joint range of motion (ROM) is restricted by muscle tension. However, it exists indirect evidence suggesting that this assumption may not hold true for some joint configurations where non-muscular structures, such as
R. Andrade   +7 more
semanticscholar   +1 more source

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