Results 1 to 10 of about 58,051 (308)
Metformin Promotes Axonal Regeneration and Functional Recovery in Diabetic Rat Model of Sciatic Nerve Transection Injury [PDF]
NeuroSci, 2022 In our previous study, metformin was able to promote nerve regeneration after sciatic nerve crushing in rats under diabetic conditions. However, a crush injury also has a strong ability to spontaneously recover.
Junxiong Ma +4 more
doaj +2 more sources
Selection of sciatic nerve injury models: implications for pathogenesis and treatment [PDF]
Frontiers in NeurologySciatic nerve injury is one of the most frequent peripheral nerve injuries in the world. The loss of motor and sensory function, along with chronic pain caused by sciatic nerve injury, significantly impacts patients’ quality of life.
Pinxi Zhou +6 more
doaj +2 more sources
A sciatic nerve gap-injury model in the rabbit [PDF]
Journal of Materials Science: Materials in Medicine, 2022 There has been an increased number of studies of nerve transection injuries with the sciatic nerve gap-injury model in the rabbit in the past 2 years. We wanted to define in greater detail what is needed to test artificial nerve guides in a sciatic nerve
Antonio Merolli +3 more
doaj +3 more sources
Salvage of Iatrogenic Sciatic Nerve Injury Caused by Operatively Treated Acetabular Fractures: Two Cases and Literature Review [PDF]
Orthopaedic SurgeryBackground While sciatic nerve injury has been described as a complication of acetabular fractures, iatrogenic nerve injury remains sparsely reported.
Peng Zhang +6 more
doaj +2 more sources
Comparison of the Effects of Perineural and Intraperitoneal Ozone Therapy on Nerve Healing in an Experimental Sciatic Nerve Injury Model [PDF]
MedicinaBackground and Objectives: The aim was to evaluate nerve healing using immunohistochemical, histological, and functional techniques and to compare the effects of two different therapeutic ozone application methods by perineural and intraperitoneal ozone ...
Burcu Ayık +7 more
doaj +2 more sources
JPRAS Open, 2022 Summary: Cerclage wiring is used to reinforce the stability of fractures and optimize plate fixations for femoral fractures such as periprosthetic fractures. However, cerclage wiring requires attention to neurovascular structures to prevent injuries.
Yuta Nakamura +3 more
doaj +2 more sources
Neural Regeneration Research, 2015 Injury severity, operative technique and nerve regeneration are important factors to consider when constructing a model of peripheral nerve injury. Here, we present a novel peripheral nerve injury model and compare it with the complete sciatic nerve ...
Xing-long Cheng +6 more
doaj +2 more sources
Detection of Neutrophils in the Sciatic Nerve Following Peripheral Nerve Injury
, 2020 Injury to the sciatic nerve leads to degeneration and debris clearance in the area distal to the injury site, a process known as Wallerian degeneration. Immune cell infiltration into the distal sciatic nerve plays a major role in the degenerative process and subsequent regeneration of the injured motor and sensory axons.
Jon P. Niemi +2 more
openalex +4 more sources
Journal of Integrative Neuroscience, 2019 Previous studies showed that brain trauma promotes repair of peripheral nerve injury by reducing scar in nerve endings. The effect of brain injury at different locations on ipsilateral rat sciatic nerve regeneration in Sprague-Dawley rats was found to ...
Haoqi Wang +5 more
doaj +2 more sources
TGF-β1 Improves Nerve Regeneration and Functional Recovery After Sciatic Nerve Injury by Alleviating Inflammation [PDF]
BiomedicinesBackground: Peripheral nerves have a certain regenerative ability, but their repair and regeneration after injury is a complex process, usually involving a large number of genes and proteins.
Maorong Jiang +8 more
doaj +2 more sources